a
Which Macrolide(s) is NOT for life-threatening diseases?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
erythromycin, clarithromycin
Which Macrolide(s) ARE active against Gm (+) cocci & bacilli?
a
Which Macrolide(s) is NOT active against KES Enterobacteriae?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
c
Which Macrolide(s) is the drug of choice to treat infections caused by Mycobacterium?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
c
Which Macrolide(s) has an FDA warning for causing heart attack?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
b
Which Macrolide is stable in acids due to its structure lacking a ketone?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
b
Which Macrolide is considered a 2nd generation Macrolide?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
d
Which Macrolide is the BEST for treating Strep?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
e
Which Macrolide inhibits transcription instead of translocation? (not a protein synthesis inhibitor)
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
e
Which Macrolide is used to treat C.diff superinfections?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
f
Fidaxomicin is absorbed orally. T/F?
e
Which Macrolide is the MOST expensive?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
d
Which Macrolide is Contraindicated in patients with myasthenia gravis?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
OCH3 substitution; blocks ketalization; available orally
What is unique about Clarithromycin's chemical structure?
Chlamydia, UTI, and RTI
Azithromycin is used to treat what conditions?
syphilis, strep, and pneumoniae
Erythromycin is used to treat what infections?
e
Which Macrolide is considered narrow spectrum?
a) Erythromycin
b) Azithromycin
c) Clarithromycin
d) Telithromycin
e) Fidaxomicin
erythromycin, azithromycin
Which Macrolide(s) are administered Orally & IV?
clarithromycin, telithromycin, fidaxomicin
Which Macrolide(s) are administered ONLY orally?
e'mycin base, erythromycin ethylsuccinate, erythromycin stearate, erythromycin lactobionate
What are the 4 dosage forms of Erythromycin?
b
Which Erythromycin dosage form comes in tablets with enteric coated particles or enteric-coated capsules?
a) erythromycin ethylsuccinate
b) e'mycin base
c) erythromycin lactobionate
d) erythromycin stearate
a
Which Erythromycin dosage form is lipophilic ester prodrug?
a) erythromycin ethylsuccinate
b) e'mycin base
c) erythromycin lactobionate
d) erythromycin stearate
d
Which Erythromycin dosage form is lipophilic, fatty acid salt?
a) erythromycin ethylsuccinate
b) e'mycin base
c) erythromycin lactobionate
d) erythromycin stearate
c
Which erythromycin dosage form is polar, sugar-based salt?
a) erythromycin ethylsuccinate
b) e'mycin base
c) erythromycin lactobionate
d) erythromycin stearate
erythromycin ethyl, erythromycin stearate
Which Erythromycin dosage form is insoluble for oral use?
c
Which Erythromycin is soluble for parenteral use (IV)?
a) erythromycin ethylsuccinate
b) e'mycin base
c) erythromycin lactobionate
d) erythromycin stearate