2022-10-09T20:41:30+03:00[Europe/Moscow] en true <p>Shelf life</p>, <p>Expiration date</p>, <p>shelf life (expiration dating period)</p>, <p>hydrolysis, oxidation, photolysis, thermal degradation, racemization</p>, <p>rate law</p>, <p>zero order</p>, <p>half-life</p>, <p>a</p>, <p>a, c</p>, <p>zero order</p>, <p>first-order</p>, <p>first order</p>, <p>zero order</p>, <p>first order</p>, <p>b</p>, <p>b</p>, <p>b</p>, <p>pseudo-first order; concentration of A doesn't change much</p>, <p>c</p>, <p>pseudo zero order</p>, <p>returns to 1st order</p>, <p>second order</p> flashcards
Kinetics

Kinetics

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  • Shelf life

    -based on time required for the drug content to decrease to 90% of the label claim (t90 ) at the recommended storage temperature.

  • Expiration date

    -the date placed on the container label of a drug product designating the time prior to which a batch of the product is expected to remain within the approved shelf life specification if stored under defined conditions, and after which it must not be used.

  • shelf life (expiration dating period)

    -the time period during which a drug product is expected to remain within the approved shelf-life specification, provided that it is stored under the conditions defined on the container label

  • hydrolysis, oxidation, photolysis, thermal degradation, racemization

    List some mechanisms of degradation?

  • rate law

    The order of a chemical reaction is determined by ______

  • zero order

    A ______ reaction is one in which the rate is independent on the concentrations of the reactants.

  • half-life

    The _______ of a zero order reaction is dependent on initial concentration.

  • a

    Fraction of drug lost changes over time.

    a. zero order

    b. first order

    c. third order

  • a, c

    Amount of drug lost over time is constant .

    a. zero order

    b. first order

    c. second order

  • zero order

    what reaction is this graph depicting?

    what reaction is this graph depicting?

  • first-order

    A _____ reaction is one where the rate of reaction is directly proportional to the concentration of one of the reactants

  • first order

    this unit applies to what reaction, time-1

  • zero order

    concentration/time applies to what reaction?

  • first order

    this graph applies to what reaction?

    this graph applies to what reaction?

  • b

    Amount lost over time is changing.

    a. zero order

    b. first order

    c. second order

  • b

    Fraction of drug lost over time is a constant.

    a. zero order

    b. first order

    c. second order

  • b

    Half life is independent of concentration and is thus a constant over time.

    a. zero order

    b. first order

    c. second order

  • pseudo-first order; concentration of A doesn't change much

    If the initial concentration of reactant A is much larger than concentration B, what type of reaction is this and why does this occur?

  • c

    Drug loss over time remains constant as long as the reservoir has enough drug remaining.

    a. pseudo- first order

    b. second order

    c. pseudo-zero order

  • pseudo zero order

    The reaction kinetics are first order process but it mimics a zero order rate of drug loss

  • returns to 1st order

    In regards to Pseudo-zero order, after all drug in reservoir is consumed, the reaction _____

  • second order

    -reaction rate depends on the concentration of two reactants