<4.4 mg/dL
What is the ionized calcium concentration that indicates hypocalcemia?
vitamin D deficiency, hypoalbuminemia, post-operative hypoparathyroidism, magnesium deficiency, hungry-bone syndrome
What are the causes of hypocalcemia? (5)
hypoparathyroidism, hypomagnesemia
Which conditions would NOT result in elevated PTH levels? (2)
GI disease
The most common cause of vitamin D deficiency in the Western world is ______.
impaired PTH signaling; target organ resistance to PTH
What can occur when a patient has hypomagnesemia? (2)
EDTA, sodium phosphate, foscarnet
What are calcium chelators that can cause hypocalcemia? (3)
inhibits the activation of calcidiol into calcitriol in the kidneys
What is FGF-23 role in calcium homeostasis?
a lack of calcitriol; impairing absorption of calcium
What would too much FGF-23 cause?
tetany, paresthesia, muscle cramps, laryngeal spasms, depression, confusion
What are the signs/symptoms of hypocalcemia? (6)
Chvostek sign
elicited by tapping the facial nerve anterior to the ear and eliciting twitching of facial muscles
Troussea's sign
elicited by inflating a blood pressure cuff above systolic blood pressure for 3 minutes and observing whether a carpal spasm is induced
dehydrocholesterol synthesized in skin by sunlight; cholecalciferol, then hydroxylated in the liver; calcidiol; then hydroxylated in kidney; calcitriol
Explain the vitamin D metabolic pathway.
false; calcium levels are still normal
Hypocalcemia related to hypoalbuminemia requires treatment. T/F?
measured Ca + 0.8(4-albumin)
Corrected Calcium formula?
60mg/min
What is the rate for calcium infusion?
b
Which is the preferred form?
a) calcium chloride
b) calcium gluconate
cardiac dysfunction; ventricular fibrillation
What can occur if we infuse calcium too quickly?
central venous access
If calcium chloride is administered, how do we do it?
< 20 ng/ml
Vitamin D deficiency is defined as