2022-02-05T01:10:54+03:00[Europe/Moscow] en true <p>Lung alveoli function</p>, <p>bowman's capsule function</p>, <p>glomerulus function</p>, <p>endothelium function</p>, <p>mesothelium function</p>, <p>capillaries function</p>, <p>kidney tubules function</p>, <p>ducts of salivary glands function</p>, <p>ducts of pancreas</p>, <p>follicles of thyroid gland function</p>, <p>Simple columnar et function</p>, <p>Keratinized Stratified Squamous ET function</p>, <p>Non-keratinized Stratified Squamous ET function</p>, <p>Stratified Columnar ET function</p>, <p>Simple Ciliated Columnar ET function</p>, <p>Pseudostratified Ciliated Columnar ET function</p>, <p>Transitional ET function</p>, <p>Glandular ET function</p>, <p>Islets of Langerhans</p>, <p>Alpha Cells</p>, <p>Beta Cells</p>, <p>Pancreas digestive system function</p>, <p>Fibroblast</p>, <p>Reticulocyte or Reticuloblast</p>, <p>Chondrocyte</p>, <p>Osteocyte</p>, <p>Adipocyte</p>, <p>Mast Cell</p>, <p>Monocyte</p>, <p>Macrophage</p>, <p>Plasma cell</p>, <p>Collagen</p> flashcards
Histology (Tissues)

Histology (Tissues)

  • Kidney - (Low mag.) 

    Tissue: Simple Squamous Epithelial Tissue

    Simple Cuboidal Epithelial Tissue

    Presence of renal corpuscles along renal tubules allows one to identify this organ as the kidney.  

  • Kidney

    Tissue: Simple Squamous Epithelial Tissue

    Simple Cuboidal Epithelial Tissue

    Low magnification slide image of the kidney. 

    Presence of renal corpuscles along renal tubules allows one to identify this organ as the kidney.  

    Often lower power allows initial identification of the organ.

  • Renal Corpuscles - (High mag. of two renal corpuscles)

    Tissue: Simple Squamous ET

    This magnification allows you to identify the outer Bowman’s capsule and the inner glomerulus.  

    Function of glomerulus is diffusion.

    Function of Bowman’s capsule is filtration.

    Consist of a glomerulus which is surrounded by the Bowman’s capsule

  • Kidney Tubules

    Tissue: Simple Cuboidal ET 

    Function: selective reabsorption 

    Near perfect cross-sections at high magnification of renal tubules

    Things reabsorbed must leave the tubules, tubules must be permeable to substance for reabsorption to occur.

      

    Examples of materials reabsorbed are glucose and amino acids.

    Anything not permeable can’t be reabsorbed and these substances are lost as urine. 

    Ex: Urea (waste).

    Consist of a lumen and wall

  • Lung (Low mag.)

    Tissue: Simple Squamous ET (alveoli)

    Function: gas exchange; diffusion of gasses

    Functional units of lungs = alveoli

     

    Blood passes through lungs inspired oxygen passes from alveoli into blood where it binds hemoglobin and is transported to all of the body’s tissues. 

    Carbon dioxide moves from blood to alveoli to be expired.

  • Lung (High mag.)

    Tissue: Simple Squamous ET (alveoli)

    Function: gas exchange; diffusion of gasses

    When looking at alveolar wall you can tell that it is cellular and can initially pick out alveoli.

    There are two alveolar walls; each belonging to their own alveolus: 2 cell layers thick; one layer corresponding to one alveoli.

  • Thyroid (Low mag.)

    Tissue: Simple Cuboidal ET

    Function: follicular cells produce thyroxine (T3/T4)

    Structures visible are thyroid follicles

    Material in center of follicle is a mixture called colloid.

    When cells are actively producing thyroxine they are thicker and appear cuboidal.  

    When cells are less active than they are not as thick and appear more squamous.

      

    Call the tissue simple cuboidal epithelial tissue but differentiate between low and high cuboidal. 

  • Thyroid (Med mag.)

    Tissue: Simple Cuboidal ET

    Function: follicular cells produce thyroxine (T3/T4)

    Structures visible are thyroid follicles

    Material in center of follicle is a mixture called colloid.

    When cells are actively producing thyroxine they are thicker and appear cuboidal.  

    When cells are less active than they are not as thick and appear more squamous.

      

    Call the tissue simple cuboidal epithelial tissue but differentiate between low and high cuboidal. 

  • Thyroid (High mag.)

    Tissue: Simple Cuboidal ET

    Function: follicular cells produce thyroxine (T3/T4)

    Structures visible are thyroid follicles

    Material in center of follicle is a mixture called colloid.

    When cells are actively producing thyroxine they are thicker and appear cuboidal.  

    When cells are less active than they are not as thick and appear more squamous.

      

    Call the tissue simple cuboidal epithelial tissue but differentiate between low and high cuboidal. 

  • Small Intestine

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Cross-sections at low magnification of the small intestine.

    Identifiable because it is convoluted into villi. 

    Contain a villus, villi, lumen.

    Villi: finger-like projections 

    Lining of stomach convoluted into villi to increase the surface area 

  • Small Intestine (intermediate mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Villi more prominent. 

    Goblet cell visible.

    Goblet cells secrete mucin that combines with water to form mucous.

  • Small Intestine (Low mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Cross-section at low magnification of small intestine.

    Identifiable because it is convoluted into villi.

  • Small Intestine (Med mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Villi more prominent 

    Goblet cells visible 

    Goblet cells secrete mucin that combines with water to form mucous.

  • Small Intestine (High mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Cells lining the villi are columnar in shape.

    Layer called the mucosa.

    Three types of cells in mucosa: 

    Columnar cells: function in absorption of nutrients (monomers)

    Goblet cells: secrete mucin

    Enteric cells: AKA brush border cells line digestive tract

  • Small Intestine (High mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Layer of mucous also visible along the free surface of cells.

     

    Cells lining the villi are columnar in shape

    Layer called the mucosa

    Three types of cells in mucosa: 

    Columnar cells: function in absorption of nutrients (monomers)

    Enteric cells: AKA brush border cells

    Lines digestive tract 

    Forms mucosa lining of villi in small intestine 

    Goblet cells: that secrete mucin

  • Small Intestine (High mag.)

    Tissue: Simple columnar ET

    Function: absorbs nutrients and water

    Goblet cells clearly visible.

    Layer of mucous also visible along the free surface of cells. 

    Cells lining the villi are columnar in shape.

    Layer called the mucosa

    Three types of cells in mucosa: 

    Columnar cells: function in absorption of nutrients (monomers)

    Goblet cells: secrete mucin

    Enteric cells: AKA brush border cells line digestive tract

  • Low skin- keratinized (low mag.)

    Tissue: Keratinized stratified squamous ET

    Functions: strength and waterproofing

     

    At this magnification can see overlying epidermis made of keratinized stratified squamous epithelial tissue .

    Epidermis of skin

    Underlying dermis made of dense irregular connective tissue.

    Dermis becomes denser as you look deeper.

  • Low skin- keratinized (low mag.)

    Tissue: Keratinized stratified squamous ET

    Functions: strength and waterproofing

     

    At this magnification can see overlying epidermis made of keratinized stratified squamous epithelial tissue .

    Epidermis of skin

    Underlying dermis made of dense irregular connective tissue.

    Dermis becomes denser as you look deeper.

  • Epidermis (high mag.)

    Tissue: Stratified Squamous ET

    Function: acts as a barrier that protects the body.

    High magnification of the deepest part of the epidermis, where it meets the dermis (interface). 

    5 layers of the epidermis of thick skin

  • Epidermis (high mag.)

    Tissue: Stratified Squamous ET

    Function: acts as a barrier that protects the body.

    High magnification of the deepest part of the epidermis, where it meets the dermis (interface). 

    5 layers of the epidermis of thick skin

  • Epidermis (high mag.)

    Tissue: Stratified Squamous ET

    Function: acts as a barrier that protects the body.

    High magnification of the deepest part of the epidermis, where it meets the dermis (interface). 

    5 layers of the epidermis of thick skin

  • Stratum Corneum 

    Tissue: Stratified Squamous ET

    Function: acts as barrier that protects body.

    High magnification of the most superficial aspect of epidermis, stratum corneum. 

    Cells don’t look like cells because they are extremely flat, anucleated, keratinized, and dead.

  • Esophagus (low mag.)

    Tissue: Stratified Squamous ET

    Function: carry food and liquid from your mouth to your stomach.

    Cross-section of non-keratinized stratified squamous tissue at low magnification 

    Makes identification of organ easy

    Non-keratinized stratified squamous epithelial tissue

  • Esophagus

    Tissue: Stratified Squamous ET

    Function: carry food and liquid from your mouth to your stomach.

    Cross-section of non-keratinized stratified squamous tissue at low magnification 

    Makes identification of organ easy

    Non-keratinized stratified squamous epithelial tissue

    Shows nature of the tissue.

  • Esophagus (High mag.)

    Tissue: Stratified Squamous ET

    Function: carry food and liquid from your mouth to your stomach.

    Only most superficial cells are squamous, deeper cells are thicker.

    Non-keratinized squamous epithelial tissue found in esophagus

    Because tissue is non-keratinized cells are not dead.

    Can see nuclei in even most superficial cells

  • Fallopian tube (low mag.)

    Tissue: simple ciliated columnar ET

    Function: transport the ova from the ovary to the uterus each month.

    Are convoluted but convolutions are irregular when compared to the small intestine.  

    Small intestine is convoluted into villi and villi are very regular. 

    Cilia are on the free surface of tissue, creating currents that propel the oocyte and embryo toward the uterus. 

    Forms mucosa.

    Contains goblet cells that secrete mucin.

    Mucous protective and lubricating.

  • Fallopian tube (med mag.)

    Tissue: simple ciliated columnar ET

    Function: transport the ova from the ovary to the uterus each month.

    Are convoluted but convolutions are irregular when compared to the small intestine.  

    Small intestine is convoluted into villi and villi are very regular. 

    Cilia are on the free surface of tissue, creating currents that propel the oocyte and embryo toward the uterus. 

    Forms mucosa.

    Contains goblet cells that secrete mucin.

    Mucous protective and lubricating.

  • Fallopian tube (high mag.)

    Tissue: simple ciliated columnar ET

    Function: transport the ova from the ovary to the uterus each month.

    Are convoluted but convolutions are irregular when compared to the small intestine.  

    Small intestine is convoluted into villi and villi are very regular. 

    Cilia are on the free surface of tissue, creating currents that propel the oocyte and embryo toward the uterus. 

    Forms mucosa.

    Contains goblet cells that secrete mucin.

    Mucous protective and lubricating.

  • Neck of mouse– Trachea and Esophagus

    Purpose is to study trachea.

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage: form C-shaped rings that prevent trachea from collapsing.

    Presence of these two different types of tissue in trachea reminds us  that organs are composed of two or more types of tissue. 

    Lines trachea and bronchi

    Function: to remove foreign material and bacteria; form lower respiratory tract

  • Trachea

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage

    This is an intermediate magnification of the trachea showing the PSCCE and the hyaline cartilage.

  • Trachea

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage

    High magnification image of trachea 

    Cilia are visible 

    PSCCE appear stratified because different types of cells found here are different heights and have nuclei at different heights

    PSCCE is not stratified because every cell does contact basement membrane.  

    Nuclei at different heights create the illusion there are multiple layers of cells.

  • Trachea

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage

    Three types of cells found here: 

    Ciliated columnar cells

    Goblet cells

    Basal cells

  • Trachea

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage

    Particulate matter is trapped in mucous layer

    Cilia move causing mucous layer to move. 

    Constant movement of the mucous layer across the free surface brings up debris from the respiratory tract.  

    Basal cells mitotically active (stem cells) replacing the other cells

  • Trachea

    Trachea lined with pseudostratified ciliated columnar epithelial tissue (PSCCE).

    Also contains hyaline cartilage

    Lines trachea and bronchi

    Function: to remove foreign material and bacteria; form lower respiratory tract

  • Ureter (low mag. through abdominopelvic region)

    Tissue: Transitional ET

    Both ureters visible

    Can see abdominal aorta and inferior vena cava

    Aorta: round cross-section 

    Vena cava: collapsed tube above and to right of aorta

    Transitional epithelial tissue

    Lines ureters and bladder

    Function: distension

  • Ureter (Higher magnification of one ureter, nature of transitional epithelial tissue begins here)

    Tissue: Transitional ET

    Both ureters visible

    Can see abdominal aorta and inferior vena cava

    Aorta: round cross-section 

    Vena cava: collapsed tube above and to right of aorta

    Transitional epithelial tissue

    Lines ureters and bladder

    Function: distension

  • Ureter (high mag.)

    Tissue: Transitional ET

    Tissue is stratified, cells are somewhat oval/egg-shaped.

    Unique tissue because tissue undergoes transition (hence name) when the urinary bladder or ureters change from being empty to full.  

    When organs full with urine they are able to distend and cells become wider and thinner 

  • Pancreas (differential stain)

    Tissue : Glandular ET

    easy to pick out Islets of Langerhans versus acinar cells 

    Function in two different systems: 

    Endocrine 

    Islets of Langerhans: endocrine system cells

    Alpha cells: secrete glucagon in response to low blood sugar. 

    Glucagon stimulate hydrolysis of glycogen (glycogenolysis).  Also stimulates hydrolysis of fat (lipolysis) when glycogen stores are low.

    Ex: fasting or prolonged exercise

    Digestive: an exocrine system 

    Pancreatic acinar cells produce pancreatic enzymes. 

    Enzymes travel through pancreatic duct to duodenum of small intestine

  • Pancreas (differential stain)

    Tissue : Glandular ET

    easy to pick out Islets of Langerhans versus acinar cells 

    Function in two different systems: 

    Endocrine 

    Islets of Langerhans: endocrine system cells

    Alpha cells: secrete glucagon in response to low blood sugar. 

    Glucagon stimulate hydrolysis of glycogen (glycogenolysis).  Also stimulates hydrolysis of fat (lipolysis) when glycogen stores are low.

    Ex: fasting or prolonged exercise

    Digestive: an exocrine system 

    Pancreatic acinar cells produce pancreatic enzymes.

    Enzymes travel through pancreatic duct to duodenum of small intestine

  • Pancreas (non differential stain)

    Tissue : Glandular ET

    Function in two different systems: 

    Endocrine 

    Islets of Langerhans: endocrine system cells

    Alpha cells: secrete glucagon in response to low blood sugar. 

    Beta cells secrete insulin in response to high blood sugar. Insulin stimulates the uptake of glucose. Glucose may be oxidized for ATP or may be used to synthesize glycogen (glycogenesis)

  • Pancreas (non differential stain)

    Tissue : Glandular ET

    Function in two different systems: 

    Endocrine 

    Islets of Langerhans: endocrine system cells

    Alpha cells: secrete glucagon in response to low blood sugar. 

    Beta cells secrete insulin in response to high blood sugar. Insulin stimulates the uptake of glucose. Glucose may be oxidized for ATP or may be used to synthesize glycogen (glycogenesis)

  • Pancreas (non differential stain)

    Tissue : Glandular ET

    Function in two different systems: 

    Endocrine 

    Islets of Langerhans: endocrine system cells

    Alpha cells: secrete glucagon in response to low blood sugar. 

    Beta cells secrete insulin in response to high blood sugar. Insulin stimulates the uptake of glucose. Glucose may be oxidized for ATP or may be used to synthesize glycogen (glycogenesis)

  • Loose connective tissue (Med mag.)

    Thicker (wider) fibers: collagen fibers

    Thinner (narrower) fibers: elastic fibers 

    Dark spots are nuclei of fibroblast cells: cells that produce collagen and elastic fibers

    Surrounds blood vessels and nerves. Fluid matrix which facilitates diffusion.

    Forms->

    Superficial fascia - binds skin to muscles

    Deep fascia - binds groups of muscles together

  • Loose connective tissue (High mag.)

    Thicker (wider) fibers: collagen fibers

    Thinner (narrower) fibers: elastic fibers 

    Dark spots are nuclei of fibroblast cells: cells that produce collagen and elastic fibers

    Surrounds blood vessels and nerves. Fluid matrix which facilitates diffusion.

    Forms->

    Superficial fascia - binds skin to muscles

    Deep fascia - binds groups of muscles together

  • Skin– Dense Irregular Connective Tissue

    Similar to slides 32 &33 

    Focus on dermis

    Can see interface between epidermis (keratinized stratified squamous epithelial tissue) and dermis, dense irregular connective tissue.  

    Superficial aspect of dermis (papillary region) more of a loose connective tissue and deeper you go, into reticular region, denser dermis becomes, dense irregular connective tissue

    Dense irregular connective tissue

    Densely packed collagen fibers, interwoven in all directions, and contains fibroblast

    Forms reticular region of dermis (lower ¾ and ⅘ ), fibrous capsules of organs, joints, and periosteum of bone

  • Skin– Dense Irregular Connective Tissue

    Similar to slides 32 &33 

    Focus on dermis

    Can see interface between epidermis (keratinized stratified squamous epithelial tissue) and dermis, dense irregular connective tissue.  

    Superficial aspect of dermis (papillary region) more of a loose connective tissue and deeper you go, into reticular region, denser dermis becomes, dense irregular connective tissue

    Dense irregular connective tissue

    Densely packed collagen fibers, interwoven in all directions, and contains fibroblast

    Forms reticular region of dermis (lower ¾ and ⅘ ), fibrous capsules of organs, joints, and periosteum of bone

  • Intermediate of dermis and hypodermis (adipose connective tissue)

    Hypodermis is one’s largest aggregation of adipose connective tissue

    Adipose Connective Tissue

    Located throughout body but mainly in hypodermis 

    Covers surface of: 

    Heart 

    Omentum

    Around kidneys

    Back of eye

    Surrounds joints

    Adipose:

    Protects

    Pads

    Stores fat (energy)

    Insulates

  • Epidermis– Dermis Interface 

    High magnification showing interface between epidermis and dermis. 

    Epidermal components that project inferiorly are called epidermal parallel pegs, dermal components that project superiorly are called dermal papilae

  • Dermis– Dense Irregular 

    High magnification deep in dermis (reticular region) of integument where connective tissue is true dense irregular connective tissue

     

    Fibers are collagen fibers and are arranged irregularly

    Fibers interwoven and interlocking

     

    Part of an animal’s skin from which leather is made

  • Hypodermis– Adipose

    High magnification of adipose connective tissue in hypodermis or subcutaneous of integument

    Structure (cells) are adipocytes: store triglycerides 

    Cells nuclei located at periphery rather than near the center 

    When cells were living they were filled with triglycerides and all the organelles were forced to the periphery.

  • Intermediate magnification of dense regular connective tissue 

    Dense regular connective tissue collage fibers are predominant type of fiber, just as in dense irregular connective tissue

    Difference is dense regular connective tissue the collagen fibers are arranged in parallel fashion

    Collagen fibers are parallel to each other and run parallel to long axis of tendon or ligament

    Dense regular connective tissue (white fibrous connective tissue)

    Densely packed collagen fibers, parallel to long axis of tendon or ligament.  Form tendons or ligaments 

    Collagen: strong, not flexible

  • High magnification of dense regular connective tissue 

    Dense regular connective tissue collage fibers are predominant type of fiber, just as in dense irregular connective tissue

    Difference is dense regular connective tissue the collagen fibers are arranged in parallel fashion

    Collagen fibers are parallel to each other and run parallel to long axis of tendon or ligament

    Dense regular connective tissue (white fibrous connective tissue)

    Densely packed collagen fibers, parallel to the long axis of tendon or ligament.  Form tendons or ligaments 

    Collagen: strong, not flexible

  • Dense regular– AKA white fibrous connective tissue 

    Densely packed collagen fibers, parallel to long axis of tendon or ligament

    Form tendons and ligaments

  • Wall of artery– elastic connective tissue 

    Elastic connective tissue in wall of aorta

    Low magnification 

    At bottom of image is lumen of the aorta

    Elastic connective tissue in arteries in sheets which run perpendicular to wall of vessel. 

    Arteries rich in elastic connective tissue, compared to veins, because blood pressure is much higher in arteries than in veins

    Elastic fibers interwoven into sheets.  Found in walls of arteries and lower respiratory tract; contain fibroblast.

    Extensible- stretch

    Elastic - recoils

  • Wall of artery– elastic connective tissue 

    Elastic connective tissue in wall of aorta

    Low magnification 

    At bottom of image is lumen of the aorta

    Elastic connective tissue in arteries in sheets which run perpendicular to wall of vessel. 

    Arteries rich in elastic connective tissue, compared to veins, because blood pressure is much higher in arteries than in veins

    Elastic fibers interwoven into sheets.  Found in walls of arteries and lower respiratory tract; contain fibroblast.

  • Wall of artery– elastic connective tissue 

    Elastic connective tissue in wall of aorta

    Low magnification 

    At bottom of image is lumen of the aorta

    Elastic connective tissue in arteries in sheets which run perpendicular to wall of vessel. 

    Arteries rich in elastic connective tissue, compared to veins, because blood pressure is much higher in arteries than in veins

    Elastic fibers interwoven into sheets.  Found in walls of arteries and lower respiratory tract; contain fibroblast.

  • Reticular connective tissue

    Reticular connective tissue taken from spleen

    Predominate fibers are reticular fibers and spots are reticulocytes or reticuloblast: cells that produce reticular fibers

    Reticulocyte refers not only to cells which produce reticular fibers but also to an immature erythrocyte. 

    Large space that is copper colored is called a sinusoid: cavity or space filled with blood

    Actually see erythrocytes in sinusoid because make up 94% of blood cells.

  • Reticular connective tissue

    Reticular fibers are irregularly arranged.

    Found in: 

    Liver

    Spleen

    Lymph Nodes

    Thymus

    Bone Marrow

    Contains: 

    Reticuloblast

    Mast cells

    Macrophages 

    Reticulocyte/Reticuloblast: produces reticular fibers

  • Adipose connective tissue

    Located throughout body but mainly in hypodermis

    Covers surface of: 

    Heart

    Omentum

    Around kidneys

    Back of eye

    Surrounds joints

    Adipose

    Protects

    Pads

    Stores fat (energy)

    Insulates

  • Adipose connective tissue

    Located throughout body but mainly in hypodermis

    Covers surface of: 

    Heart

    Omentum

    Around kidneys

    Back of eye

    Surrounds joints

    Adipose

    Protects

    Pads

    Stores fat (energy)

    Insulates

  • Same images as slides 52 and 58; taken from the trachea

    C-shaped rings of the trachea are made of hyaline cartilage connective tissue to prevent it from collapsing 

    Connective tissue provides support, physical and metabolic, for epithelial tissue

    Epithelial tissue is avascular and connective is vascular, mature cartilage is avascular,  why it is very difficult for torn cartilage to heal 

    Cartilage tissue

    Composed of chondrocytes contained within elastic matrix 

    Chondrocytes contained within spaces called lacunae.  Lacunae may contain one of many chondrocytes.

    Mature cartilage avascular so very slow to heal after injury

  • Same images as slides 52 and 58; taken from the trachea

    Hyaline Cartilage

    Most common in the body 

    Known as gristle in meat

    Forms: 

    Articular surfaces of bones (articular cartilage) 

    Rings in trachea and upper respiratory tract

    Nasal septum

    Costal cartilage between ribs and sternum (sternocostal joints)

    Fetal skeleton 

    High power of hyaline cartilage, can discern spaces called lacunae that contain chondrocytes

  • Elastic cartilage connective tissue

    Intermediate magnification of external ear of Mus musculus: common mouse

    Intermediate aspect of external ear is composed of elastic cartilage connective tissue 

    There is skin of either side of the elastic cartilage

    On each side of the elastic cartilage is dense irregular connective tissue (dermis) and keratinized stratified squamous epithelial tissue (epidermis)

    Elastic cartilage connective tissue: 

    Very flexible cartilage containing elastic fibers that are found in: 

    External ear

    Epiglottis 

    Larynx 

    Auditory canal

  • Elastic cartilage connective tissue

    High power magnification of external ear of Mus musculus: common mouse

    Intermediate aspect of external ear is composed of elastic cartilage connective tissue

    Same ultrastructure as discussed in hyaline cartilage, lacunae and chondrocytes.  

    Very easy to see elastic fibers.

    Elastic cartilage connective tissue:

    Very flexible cartilage containing elastic fibers that are found in:

    External ear

    Epiglottis

    Larynx

    Auditory canal

  • Elastic cartilage connective tissue (skin of ear)

    High power magnification view of area above (not anatomical) elastic cartilage

    Easy to see this is skin

    Elastic cartilage connective tissue:

    Very flexible cartilage containing elastic fibers that are found in:

    External ear

    Epiglottis

    Larynx

    Auditory canal

  • Fibrocartilage connective tissue

    Intermediate magnification 

    Fibrocartilage: strong,built to withstand compression; well suited for menisci of knees, intervertebral joints, symphysis pubis.

    Blue fibers: collagen fibers; characteristic of fibrocartilage

    Red spots: chondrocytes within their lacunae, same ultrastructure as discussed in hyaline cartilage

  • Fibrocartilage connective tissue

    Intermediate magnification 

    Fibrocartilage: strong, built to withstand compression; well suited for menisci of knees, intervertebral joints, symphysis pubis.

    Blue fibers: collagen fibers; characteristic of fibrocartilage

    Red spots: chondrocytes within their lacunae, same ultrastructure as discussed in hyaline cartilage

  • Blood connective tissue– AKA whole blood

     

    Shows two of three basic types of blood cells: erythrocytes and leukocytes; thrombocytes not seen 

    Most cells erythrocytes: comprise 94% of blood cells

    One large cell in center is a leukocyte, specifically a neutrophil

    There are few leukocytes seen because they only make up 0.14% of blood cells.  

    Some erythrocytes are lighter in center and presents like a nucleus

    Blood: about 45% cells (formed elements) and 55% plasma

    Erythrocytes (RBC): 94% of formed elements

    Function: carry oxygen

    Mature blood cells: anucleated and packed with hemoglobin

    Hemoglobin: protein that binds oxygen

  • Lung alveoli function

    diffusion of gasses (simple squamous et)

  • bowman's capsule function

    filtration (simple squamous et)

  • glomerulus function

    diffusion (simple squamous et)

  • endothelium function

    line blood vessels to provide smooth surface (simple squamous et)

  • mesothelium function

    cover organs, support (simple squamous et)

  • capillaries function

    diffusion of gasses (simple squamous et)

  • kidney tubules function

    selective reabsorption (simple cuboidal et)

  • ducts of salivary glands function

    secretion (simple cuboidal et)

  • ducts of pancreas

    secretion (simple cuboidal et)

  • follicles of thyroid gland function

    produce hormones:

    thyroxine (t3, t4) - increase metabolic rate.

    calcitonin-inhibit osteoclasts, stop decrease in bone mass

    parathyroid hrmone (pth)- stimulates osteoclasts, increase bone Ca, decrease bone mass

  • Simple columnar et function

    Lines the digestive tract. Forms the mucosa lining of the villi in the small intestine.  Contains goblet cells which secrete mucin.  Mucin and water combine to form mucous.  Mucous is protective and lubricating.  The function is absorption of nutrients.

  • Keratinized Stratified Squamous ET function

    Epidermis of skin. Functions are strength and waterproofing

  • Non-keratinized Stratified Squamous ET function

    Lines oral cavity, nasal cavity, pharynx, esophagus, vagina, anal canal. Functions are to protect against abrasion and maintain moisture.

  • Stratified Columnar ET function

    (AKA stratified cuboidal) ducts of sweat glands and mammary glands. The function is to provide structural support.

    parts of the epiglottis, pharynx, anus, urethra, and excretory ducts function is to provide protection.

  • Simple Ciliated Columnar ET function

    Lines uterine tubes (fallopian tubes) function is to transport material through lumen.

  • Pseudostratified Ciliated Columnar ET function

    Lines trachea and bronchi. Function is to remove foreign material and bacteria and form lower respiratory tract.

  • Transitional ET function

    Lines ureters and urinary bladder. Function is distension.

  • Glandular ET function

    pancreas functions in two different systems: endocrine and digestive

  • Islets of Langerhans

    (endocrine system cells)

  • Alpha Cells

    secrete glucagon in response to LOW blood sugar.

    Glucagon stimulates hydrolysis of glycogen. (glycogenolysis).

    Glucagon stimulates hydrolysis of fat (liposis) WHEN glycogen stores are low. (fasting or prolonged exercise)

  • Beta Cells

    secrete insulin in response to HIGH blood sugar.

    Insulin stimulates uptake of glucose.

    Glucose may be oxidized for ATP or may be used to synthesize glycogen (glycogenesis).

  • Pancreas digestive system function

    acinar cells produce pancreatic enzymes.

    These enzymes travel through pancreatic duct to the duodenum of the small intestine.

  • Fibroblast

    produce collagen and elastic fibers

  • Reticulocyte or Reticuloblast

    Produce reticular fibers

  • Chondrocyte

    cartilage cell

  • Osteocyte

    Bone cell

  • Adipocyte

    fat cell

  • Mast Cell

    produces heparin and histamine

  • Monocyte

    Phagocytic WBC in the vasculature

  • Macrophage

    A monocyte that is in the interstitial space

  • Plasma cell

    produces antibodies

  • Collagen

    strong, not flexible