Hosam Mohamed-
large surface; vascularized
Alveoli contain a _________ area & are highly _________.
-
average particle size/distribution, shape, density
What are the Critical properties of Particles? (3)
-
0.5-10 microns
Fine dispersion =
-
1-5 microns
Target micron size for inhalation?
-
c
Particles deposited in URT.
a) Brownian diffusion
b) Gravitational sedimentation
c) Intertial impaction
-
< 0.5 microns
Brownian diffusion =
-
0.5-6 microns
Gravitational sedimentation =
-
elongated; spherical
________ shaped particles are delivered deeper into the lungs than ______
particles.
-
b
Which is NOT pressurized?
a) aerosol
b) spray
-
antimicrobial
When sprays are supplied as multidose containers, _______ preservative may be necessary.
-
b
Which can bind to drug substances & reduce efficacy?
a) benzyl alcohol
b) benzalkonium chloride
c) mercury
-
water
What is used as the solvent/vehicle in Nasal sprays?
-
4.5-7
pH outside _______ is irritating.
-
a,c
Which is an ion exchange resin?
a) gum
b) patch
c) lozenge
-
b
Which is a polymer matrix?
a) gum
b) patch
c) lozenge
-
start chewing until you feel warm tingle; move gum to cheek/gums; when tingle is almost gone start chewing again; repeat until tingle is gone
Patient counseling on Nictonie gum?
