γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a psychoactive drug.
Tetrahydrocannabinol
Tetrahydrocannabinol (THC, dronabinol by INN), or more precisely its main isomer (−)-trans-Δ9-tetrahydrocannabinol, is the principal psychoactive constituent (or cannabinoid) of cannabis.
Methylone
Methylone (also known as "3,4-methylenedioxy-N-methylcathinone", "MDMC", "βk-MDMA" and by the slang term "M1") is an empathogen and stimulant psychoactive drug.
Amphetamine
Amphetamine (contracted from alpha‑methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
Diethyl ether
Diethyl ether or simply ether, is an organic compound in the ether class with the formula (C2H5)2O.
Heroin
Heroin is an opioid drug typically used as a recreational drug for its euphoric effects.
Ketamine
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.
MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
Methadone
Methadone, sold under the brand names Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence.
Morphine
Morphine is a pain medication of the opiate type which is found naturally in a number of plants and animals.
Nitrous oxide
Nitrous oxide, commonly known as laughing gas, nitrous, nitro, or NOS is a chemical compound with the formula N2O.
Opium
Opium (poppy tears, with the scientific name: Lachryma papaveris) is the dried latex obtained from the opium poppy (scientific name: Papaver somniferum).
Toluene
Toluene /ˈtɒljuːiːn/, also known as toluol /ˈtɒljuːɒl/, is a colorless, water-insoluble liquid with the smell associated with paint thinners.
Phenethylamine
Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound and a natural monoamine alkaloid, a trace amine, and also the name of a class of chemicals with many members that are well known for their psychoactive and stimulant effects.
Tramadol
Tramadol, sold under the brandname Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain.
Anandamide
Anandamide, also known as N-arachidonoylethanolamine or AEA, is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid) an essential ω-6 polyunsaturated fatty acid.
Fentanyl
Fentanyl (also known as fentanil) is a potent, synthetic opioid pain medication with a rapid onset and short duration of action.
Hydrocodone
Hydrocodone, also known as dihydrocodeinone, is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids found in the opium poppy.
Hydrocodone/paracetamol
Hydrocodone/paracetamol, also known as hydrocodone/acetaminophen or hydrocodone/APAP and marketed under the trade name Vicodin among others, is the combination of an opioid pain medication, hydrocodone, with paracetamol (acetaminophen).
Hydromorphone
Hydromorphone, also known as dihydromorphinone, and sold under the brand names Dilaudid among others, is a centrally acting pain medication of the opioid class.
Oxycodone
Oxycodone, known originally in Germany (where it was developed) as dihydroxycodeinone or eukodal, is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the opium poppy.
Oxymorphone
Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful semi-synthetic opioid analgesic (painkiller) first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other countries around the same time.
Dextrorphan
Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen.
Beta-Endorphin
β-Endorphin is an endogenous opioid neuropeptide found in the neurons of both the central and peripheral nervous system.
ALD-52
ALD-52, also known as 1-acetyl-LSD, is a chemical analogue of lysergic acid diethylamide (LSD).
Pethidine
Pethidine, also known as meperidine and Demerol, is a synthetic opioid pain medication of the phenylpiperidine class.
Mephedrone
Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes.
Methcathinone
Methcathinone (α-methylamino-propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" ) is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone.
Methylenedioxypyrovalerone
Methylenedioxypyrovalerone (MDPV) is a stimulant of the cathinone class which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI).
Dextroamphetamine
Dextroamphetamine (American English) or dexamfetamine (Commonwealth English) is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Buprenorphine
Buprenorphine is a semisynthetic opioid derivative of thebaine.
Mitragynine
Mitragynine is an indole-based opioid and the most abundant active alkaloid in the plant Mitragyna speciosa, commonly known as kratom and biak-biak.
Phendimetrazine
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
Cathine
Cathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant.
Phencyclidine
Phencyclidine (PCP), also known as angel dust and Sernyl among others, is a dissociative drug.
Dihydromorphine
Dihydromorphine (Paramorfan, Paramorphan) is a semi-synthetic opioid structurally related to and derived from morphine.
Ketobemidone
Ketobemidone (Cliradon, Ketogan, Ketodur, Cymidon, Ketorax, &c.) is a powerful opioid analgesic.
Levorphanol
Levorphanol /lɛvaʊrfɑːnɒl/ (brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain.
Phenmetrazine
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.
Benzylpiperazine
Benzylpiperazine (BZP) is a recreational drug with euphoriant and stimulant properties.
4-Methylaminorex
4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline class that was first synthesized in 1960 by McNeil Laboratories.
Diacetyldihydromorphine
Diacetyldihydromorphine (also known as Paralaudin, dihydroheroin or acetylmorphinol) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of severe pain such as that caused by terminal cancer, as another form of diamorphine (also commonly known as Heroin).
Propylhexedrine
Propylhexedrine (Benzedrex, Obesin) is a stimulant drug that is used medicinally as a nasal decongestant (for relief of congestion due to colds, allergies and allergic rhinitis) and recreationally for its psychostimulant effects.
3,4-Methylenedioxy-N-ethylamphetamine
3,4-Methylenedioxy-N-ethylamphetamine ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug.
5-Methoxymethylone
5-Methoxy-Methylone (also known as 2-A1MP and βk-MMDMA) is a chemical compound of the cathinone class which has been sold online as a designer drug.
Carisoprodol
Carisoprodol, marketed under the brand name Soma among others, is a prescription drug marketed since 1959.
N-Ethylnorketamine
N-Ethylnorketamine (ethketamine, NENK, 2-Cl-2'-Oxo-PCE) is a designer drug which is presumed to have similar properties to ketamine, a dissociative anesthetic drug with hallucinogenic and sedative effects.
Amfonelic acid
Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties.
Neurobiological effects of physical exercise
The neurobiological effects of physical exercise are numerous and involve a wide range of interrelated effects on brain structure, brain function, and cognition.
3-Fluoromethamphetamine
3-Fluoromethamphetamine (3-FMA) is a stimulant drug from the amphetamine class that has been sold online as a designer drug.
Adderall
Adderall is a combination drug containing salts of the two enantiomers of amphetamine, a central nervous system (CNS) stimulant of the phenethylamine class.
3,4-Methylenedioxyamphetamine
3,4-Methylenedioxeamphetamine (MDA), also known as tenamfetamine (INN), is a psychoactive drug of the substituted methylenedioxyphenethylamine and substituted amphetamine classes of drugs that is consumed primarily for its entactogenic, psychedelic, and psychostimulant effects.
Acetylfentanyl
Acetylfentanyl (acetyl fentanyl) is an opioid analgesic drug that is an analog of fentanyl.
4-Fluoromethamphetamine
4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine.
Noroxymorphone
Noroxymorphone is an opioid which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others.
Nicomorphine
Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine.
Gamma-Hydroxyvaleric acid
γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB).
Levopropylhexedrine
Levopropylhexedrine (Eventin) is a psychostimulant used as an anorectic in Germany and patented by Smith Kline & French in 1947.
Methylenedioxycathinone
3,4-Methylenedioxycathinone (also known as MDC, Nitrilone, Amylone and βk-MDA) is an empathogen and stimulant of the phenethylamine, amphetamine, and cathinone classes and the β-keto analogue of MDA.
Cocaethylene
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine.
Dibutyrylmorphine
Dibutyrylmorphine (also known as dibutanoylmorphine) is the 3,6-dibutyryl ester of morphine, first synthesized by the CR Alders Wright organization in the United Kingdom in 1875.
Mitragynine pseudoindoxyl
Mitragynine pseudoindoxyl is a semi-synthetic compound derived from natural mitragynine found in the plant Mitragyna speciosa, commonly known as Kratom.
Benzhydrocodone
Benzhydrocodone (INN) (contracted from benzoate-hydrocodone) is a opioid prodrug of the morphinan class.
γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a psychoactive drug.
Tetrahydrocannabinol
Tetrahydrocannabinol (THC, dronabinol by INN), or more precisely its main isomer (−)-trans-Δ9-tetrahydrocannabinol, is the principal psychoactive constituent (or cannabinoid) of cannabis.
Methylone
Methylone (also known as "3,4-methylenedioxy-N-methylcathinone", "MDMC", "βk-MDMA" and by the slang term "M1") is an empathogen and stimulant psychoactive drug.
Amphetamine
Amphetamine (contracted from alpha‑methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
Diethyl ether
Diethyl ether or simply ether, is an organic compound in the ether class with the formula (C2H5)2O.
Heroin
Heroin is an opioid drug typically used as a recreational drug for its euphoric effects.
Ketamine
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.
MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
Methadone
Methadone, sold under the brand names Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence.
Morphine
Morphine is a pain medication of the opiate type which is found naturally in a number of plants and animals.
Nitrous oxide
Nitrous oxide, commonly known as laughing gas, nitrous, nitro, or NOS is a chemical compound with the formula N2O.
Opium
Opium (poppy tears, with the scientific name: Lachryma papaveris) is the dried latex obtained from the opium poppy (scientific name: Papaver somniferum).
Toluene
Toluene /ˈtɒljuːiːn/, also known as toluol /ˈtɒljuːɒl/, is a colorless, water-insoluble liquid with the smell associated with paint thinners.
Phenethylamine
Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound and a natural monoamine alkaloid, a trace amine, and also the name of a class of chemicals with many members that are well known for their psychoactive and stimulant effects.
Tramadol
Tramadol, sold under the brandname Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain.
Anandamide
Anandamide, also known as N-arachidonoylethanolamine or AEA, is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid) an essential ω-6 polyunsaturated fatty acid.
Fentanyl
Fentanyl (also known as fentanil) is a potent, synthetic opioid pain medication with a rapid onset and short duration of action.
Hydrocodone
Hydrocodone, also known as dihydrocodeinone, is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids found in the opium poppy.
Hydrocodone/paracetamol
Hydrocodone/paracetamol, also known as hydrocodone/acetaminophen or hydrocodone/APAP and marketed under the trade name Vicodin among others, is the combination of an opioid pain medication, hydrocodone, with paracetamol (acetaminophen).
Hydromorphone
Hydromorphone, also known as dihydromorphinone, and sold under the brand names Dilaudid among others, is a centrally acting pain medication of the opioid class.
Oxycodone
Oxycodone, known originally in Germany (where it was developed) as dihydroxycodeinone or eukodal, is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the opium poppy.
Oxymorphone
Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful semi-synthetic opioid analgesic (painkiller) first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other countries around the same time.
Dextrorphan
Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen.
Beta-Endorphin
β-Endorphin is an endogenous opioid neuropeptide found in the neurons of both the central and peripheral nervous system.
ALD-52
ALD-52, also known as 1-acetyl-LSD, is a chemical analogue of lysergic acid diethylamide (LSD).
Pethidine
Pethidine, also known as meperidine and Demerol, is a synthetic opioid pain medication of the phenylpiperidine class.
Mephedrone
Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes.
Methcathinone
Methcathinone (α-methylamino-propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" ) is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone.
Methylenedioxypyrovalerone
Methylenedioxypyrovalerone (MDPV) is a stimulant of the cathinone class which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI).
Dextroamphetamine
Dextroamphetamine (American English) or dexamfetamine (Commonwealth English) is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Buprenorphine
Buprenorphine is a semisynthetic opioid derivative of thebaine.
Mitragynine
Mitragynine is an indole-based opioid and the most abundant active alkaloid in the plant Mitragyna speciosa, commonly known as kratom and biak-biak.
Phendimetrazine
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
Cathine
Cathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant.
Phencyclidine
Phencyclidine (PCP), also known as angel dust and Sernyl among others, is a dissociative drug.
Dihydromorphine
Dihydromorphine (Paramorfan, Paramorphan) is a semi-synthetic opioid structurally related to and derived from morphine.
Ketobemidone
Ketobemidone (Cliradon, Ketogan, Ketodur, Cymidon, Ketorax, &c.) is a powerful opioid analgesic.
Levorphanol
Levorphanol /lɛvaʊrfɑːnɒl/ (brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain.
Phenmetrazine
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.
Benzylpiperazine
Benzylpiperazine (BZP) is a recreational drug with euphoriant and stimulant properties.
4-Methylaminorex
4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline class that was first synthesized in 1960 by McNeil Laboratories.
Diacetyldihydromorphine
Diacetyldihydromorphine (also known as Paralaudin, dihydroheroin or acetylmorphinol) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of severe pain such as that caused by terminal cancer, as another form of diamorphine (also commonly known as Heroin).
Propylhexedrine
Propylhexedrine (Benzedrex, Obesin) is a stimulant drug that is used medicinally as a nasal decongestant (for relief of congestion due to colds, allergies and allergic rhinitis) and recreationally for its psychostimulant effects.
3,4-Methylenedioxy-N-ethylamphetamine
3,4-Methylenedioxy-N-ethylamphetamine ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug.
5-Methoxymethylone
5-Methoxy-Methylone (also known as 2-A1MP and βk-MMDMA) is a chemical compound of the cathinone class which has been sold online as a designer drug.
Carisoprodol
Carisoprodol, marketed under the brand name Soma among others, is a prescription drug marketed since 1959.
N-Ethylnorketamine
N-Ethylnorketamine (ethketamine, NENK, 2-Cl-2'-Oxo-PCE) is a designer drug which is presumed to have similar properties to ketamine, a dissociative anesthetic drug with hallucinogenic and sedative effects.
Amfonelic acid
Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties.
Neurobiological effects of physical exercise
The neurobiological effects of physical exercise are numerous and involve a wide range of interrelated effects on brain structure, brain function, and cognition.
3-Fluoromethamphetamine
3-Fluoromethamphetamine (3-FMA) is a stimulant drug from the amphetamine class that has been sold online as a designer drug.
Adderall
Adderall is a combination drug containing salts of the two enantiomers of amphetamine, a central nervous system (CNS) stimulant of the phenethylamine class.
3,4-Methylenedioxyamphetamine
3,4-Methylenedioxeamphetamine (MDA), also known as tenamfetamine (INN), is a psychoactive drug of the substituted methylenedioxyphenethylamine and substituted amphetamine classes of drugs that is consumed primarily for its entactogenic, psychedelic, and psychostimulant effects.
Acetylfentanyl
Acetylfentanyl (acetyl fentanyl) is an opioid analgesic drug that is an analog of fentanyl.
4-Fluoromethamphetamine
4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine.
Noroxymorphone
Noroxymorphone is an opioid which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others.
Nicomorphine
Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine.
Gamma-Hydroxyvaleric acid
γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB).
Levopropylhexedrine
Levopropylhexedrine (Eventin) is a psychostimulant used as an anorectic in Germany and patented by Smith Kline & French in 1947.
Methylenedioxycathinone
3,4-Methylenedioxycathinone (also known as MDC, Nitrilone, Amylone and βk-MDA) is an empathogen and stimulant of the phenethylamine, amphetamine, and cathinone classes and the β-keto analogue of MDA.
Cocaethylene
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine.
Dibutyrylmorphine
Dibutyrylmorphine (also known as dibutanoylmorphine) is the 3,6-dibutyryl ester of morphine, first synthesized by the CR Alders Wright organization in the United Kingdom in 1875.
Mitragynine pseudoindoxyl
Mitragynine pseudoindoxyl is a semi-synthetic compound derived from natural mitragynine found in the plant Mitragyna speciosa, commonly known as Kratom.
Benzhydrocodone
Benzhydrocodone (INN) (contracted from benzoate-hydrocodone) is a opioid prodrug of the morphinan class.
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