2017-07-30T06:09:31+03:00[Europe/Moscow] en true Histone deacetylase, Induced pluripotent stem cell, Sex-determination system, Histone, Methylation, MicroRNA, Histone acetyltransferase, DNA methyltransferase, 5-Hydroxymethylcytosine, Histone methyltransferase, Neurobiological effects of physical exercise, Methylated DNA immunoprecipitation, Transgenerational epigenetic inheritance, Heterochromatin protein 1, International Human Epigenome Consortium flashcards


  • Histone deacetylase
    Histone deacetylases (EC, HDAC) are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on a histone, allowing the histones to wrap the DNA more tightly.
  • Induced pluripotent stem cell
    Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells.
  • Sex-determination system
    A sex-determination system is a biological system that determines the development of sexual characteristics in an organism.
  • Histone
    In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes.
  • Methylation
    In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
  • MicroRNA
    A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
  • Histone acetyltransferase
    Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl CoA to form ε-N-acetyllysine.
  • DNA methyltransferase
    In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.
  • 5-Hydroxymethylcytosine
    5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base.
  • Histone methyltransferase
    Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.
  • Neurobiological effects of physical exercise
    The neurobiological effects of physical exercise are numerous and involve a wide range of interrelated effects on brain structure, brain function, and cognition.
  • Methylated DNA immunoprecipitation
    Methylated DNA immunoprecipitation (MeDIP or mDIP) is a large-scale (chromosome- or genome-wide) purification technique in molecular biology that is used to enrich for methylated DNA sequences.
  • Transgenerational epigenetic inheritance
    Transgenerational epigenetic inheritance is the transmittance of information from one generation of an organism to the next (e.g., parent–child transmittance) that affects the traits of offspring without alteration of the primary structure of DNA (i.e., the sequence of nucleotides).
  • Heterochromatin protein 1
    The family of Heterochromatin Protein 1 (HP1) ("Chromobox Homolog", CBX) consists of highly conserved proteins, which have important functions in the cell nucleus.
  • International Human Epigenome Consortium
    The International Human Epigenome Consortium (IHEC) is a scientific organization, founded in 2010, that helps to coordinate global efforts in the field of Epigenomics.