Drugs acting on the respiratory system

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA.

Fluticasone is a synthetic glucocorticoid.

Pirfenidone (INN, BAN) is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF).

Lucinactant (trade name Surfaxin) is a liquid medication used to treat infant respiratory distress syndrome.

Guacetisal is a drug that has been used to treat inflammatory respiratory diseases.

Denufosol (INN) is an inhaled drug for the treatment of cystic fibrosis, being developed by Inspire Pharmaceuticals and sponsored by the Cystic Fibrosis Foundation.

Poractant alfa is a pulmonary surfactant sold under the brand name Curosurf by Chiesi Farmaceutici.

The combination of the drugs guaifenesin and phenylephrine is a preparation against the symptoms of cold, flu and allergy.

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein.

Fluticasone furoate/vilanterol (trade names Breo Ellipta and Relvar Ellipta) is a combination drug for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.

Umeclidinium bromide (trade name Incruse Ellipta, GSK) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD).

Umeclidinium bromide/vilanterol (trade name Anoro Ellipta) is a combination drug approved for the treatment of chronic obstructive pulmonary disease (COPD).