DNA repair

2017-07-31T11:19:34+03:00[Europe/Moscow] en true Ku (protein), Poly ADP ribose polymerase, DNA mismatch repair, Photolyase, DNA glycosylase, Very short patch repair, Excinuclease, 8-Oxoguanine, RecA, Free radical damage to DNA, DNA repair-deficiency disorder, XPG I protein domain flashcards DNA repair
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  • Ku (protein)
    Ku is a dimeric protein complex that binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair.
  • Poly ADP ribose polymerase
    Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes involving mainly DNA repair and programmed cell death.
  • DNA mismatch repair
    DNA mismatch repair is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.
  • Photolyase
    Photolyases (EC 4.1.99.3) are DNA repair enzymes that repair damage caused by exposure to ultraviolet light.
  • DNA glycosylase
    DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.
  • Very short patch repair
    Very short patch (VSP) repair is a DNA repair system that removes GT mismatches created by the deamination of 5-methylcytosine to thymine.
  • Excinuclease
    Excision endonuclease, also known as excinuclease or UV-Specific Endonuclease, is a nuclease (enzyme) which excises a fragment of nucleotides during DNA repair.
  • 8-Oxoguanine
    8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species and can result in a mismatched pairing with adenine resulting in G to T and C to A substitutions in the genome.
  • RecA
    RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA.
  • Free radical damage to DNA
    Free radical damage to DNA can occur as a result of exposure to UV radiation or to radiomimetic compounds.
  • DNA repair-deficiency disorder
    A DNA repair-deficiency disorder is a medical condition due to reduced functionality of DNA repair.
  • XPG I protein domain
    In molecular biology, the XPG-I is a protein domain found on Xeroderma Pigmentosum Complementation Group G (XPG) protein.