______________ refers to the major means of ________ with some ____________
Breaking down foods _______________
Segmentation
mixing
propulsion
mechanically
During segmentation, _______________ segments of the alimentary canal ________ and ______ to move food __________ and _____________
nonadjacent
contract
relax
forwards
backwards
___________ is the major means of ____________
Moving foods _________
peristalsis
propulsion
distally
During peristalsis, ___________ segments of the alimentary canal organs alternatively _________ and ________ to ________ food along the tract with some _________
adjacent
contract
relax
propel
mixing
The ___________________ is the serous membrane of the abdominopelvic cavity
Peritoneum
The ___________ ______________ covers the _________ ____________ of most _________ organs and is continuous with the parietal peritoneum
Visceral Peritoneum
external surface
digestive
The ___________ _____________ lines the ______________ cavity wall
Parietal Peritoneum
abdominopelvic
The _______________ _________ is the slit-like potential space between _________ and _____________ ___________
Peritoneal Cavity
visceral
parietal peritoneum
The ______________ __________contains slippery fluid secreted by the ________membrane to reduce _______ of mobile __________ _________
peritoneal cavity
serous
friction
digestive organs
The ____________ is the double layer of ___________, two ______ membranes back to back
Mesentery
peritoneum
serous
Mesentery
Extends to the ___________ organs from the ____ wall
Provides routes to digestive viscera for
______ _______
__________
________
Holds ______ in place
Stores ___
digestive
body
blood vessels
lymphatics
nerves
organs
fat
These structures receive blood from what artery?
Spleen
Liver
Stomach
Inferior Esophagus
celiac trunk artery
These structures receive blood from what artery?
Small intestines
Appendix
Cecum
Ascending colon
Part of the transverse colon
Adrenal Glands
Kidneys
Ovaries
Uterine tubes
Testes
superior mesenteric artery
These structures receive blood from what artery?
Distal Large Intestine
Posterior abdominal wall
Sacrum
Coccyx
Lower abdominal wall
Pelvic organs
Lower limbs
Inferior mesenteric artery
Nerve supply of the alimentary canal
enteric nervous system
________ ________
Composed of two plexuses found in the walls of the alimentary canal
_________ ________ ______
_________ ________ ______
enteric neurons
submucosal nerve plexus
myenteric nerve plexus
which enteric plexus located between circular and longitudinal muscle layers of the muscularis externa?
myenteric nerve plexus
which enteric plexus is located in the submucosa?
submucosal nerve plexus
Enteric nervous system
Communicate and regulate _________ ________ activity
Provide the major ______ _______ to the GI tract
Control GI tract ________
Motion
_____ and ____ reflex arcs
digestive system
nerve supply
motility
short
long
_______ __________are mediated entirely by enteric nervous system plexuses in response to ________ in the GI tract
Automatic control over _____________ and ____________
Involves _____________ ____and reflex arcs between _______ ________ in the same or different organs
short reflexes
stimuli
automatic
segmentation
peristalsis
pacemaker cells
enteric neurons
_______ __________ involves ____ ____________ ______ and extrinsic ____________ _________
Enteric nervous system _________ __________ ___________ afferents to CNS
Dual innervation from sympathetic and parasympathetic nervous systems
Allows for extrinsic controls to influence digestive activity
Parasympathetic
___________
Sympathetic
___________
long reflexes
CNS integration centers
autonomic nerves
visceral sensory fibers
excitatory
inhibitory
_______________ refers to organs that lie posterior to the peritoneum and adhere to the dorsal abdominal wall
Retroperitoneal
___________ _______ ____________ refers to veins connecting two capillary beds
Carries __________ rich blood that sometimes has ______ and microorganisms from the __________ ________ to the _____ to be __________ before it reaches the rest of the body
Hepatic portal circulation
nutrient
toxins
digestive organs
liver
treated
Role of liver in digestion
____ produced by liver ___________ ____ and enhances
Fat digestion
Absorption of fatty acids, monoglycerides, cholesterol, phospholipids, and fat-soluble vitamins
bile
emulsifies fats
The _________ contains a mucous membrane, lamina propria, and muscularis Mucosae
mucosa
in the mucosa, the mucous membrane is composed of ________ _________ ___________ that secretes _______ that contains digestive _________ , and __________
simple columnar epithelium
mucus
enzymes
hormones
in the mucosa, the ________ _________ nourishes the ____________ and _______ digested _________
lamina propria
epithelium
absorbs
nutrients
in the mucosa, the __________ ___________ contains ________ ________ cells produce __________ that help absorb the end products of _________ into the _____
muscularis mucosae
smooth muscle
movement
digestion
blood
The layer deep to the mucosa, the ___________ is composed of __________ ___________ _________
It contains a rich supply of ________ ________, ___________ __________, and _______ ________ that supply the surrounding tissues of the GI tract
________ ________ enable stomach to regain its shape after storing a large meal
submucosa
areolar connective tissue
blood vessels
lymphoid follicles
nerve fibers
elastic fibers
The layer deep to the submucosa is the __________ _________, it contains ________ _______ cells and two layers, an ______ ________ _________ and an ______ ___________ ________
This layer responsible for ______________ and ___________
Muscularis externa
smooth muscle
inner circular layer
outer longitudinal layer
segmentation
peristalsis
The __________ ___________ of the muscularis externa can thicken to form __________ that act as _____ to control food passage between organs and prevent __________
circular layer
sphincters
valves
backflow
The layer deep to the muscularis externa is the ________ it is composed of _______ ________ _________ covered with ______________ which is a single layer of _______ ________ _________ cells
serosa
areolar connective tissue
mesothelium
simple squamous epithelial
In the __________ of thoracic cavity the serosa is replaced by the __________, which is ________ _________ ________
esophagus
adventitia
dense connective tissue
The ________________ of the serosa facilitates _________ and secretes __________ fluid
Mesothelium
diffusion
lubricating
___________ ________ _______ cushions other tissues, contains macrophages for bacteria, plays a role in inflammation, holds and conveys tissue fluid
areolar connective tissue
Parasympathetic nervous system’s role in GI function
Oral cavity
_______ __________
salvia secretion
Parasympathetic nervous system’s role in GI function
Digestive tract organs
Increases _______ through _________
Increases amount of _________ by digestive organs
Relaxes __________ to allow ___________
motility
peristalsis
secretion
sphincters
propulsion
Parasympathetic nervous system’s role in GI function
Liver
Increases ________ uptake from _______
glucose
blood
Parasympathetic nervous system’s role in GI function
Gallbladder
______ gallbladder to expel _____
excites
bile
Regulation of gastric secretion
________ _______ and _______ _______ reflexes
Parasympathetic release of _______________
Increases _________ activity of all ______
vagus nerve
enteric nerve
acetylcholine
secretory
glands
Saliva
_________ the mouth
__________ food chemicals so they can be treated
_________ food and helps compact it into a ______
Contains the enzyme ________ that begins the digestion of _______ foods
cleanses
dissolves
moistens
bolus
amylase
starchy
Digestive processes of the mouth
1. ________
Food enters the mouth
2, Begins __________
mechanical breakdown by chewing
Voluntary and involuntary
3. Initiates ___________ by swallowing
4. Starts the digestion of ________________
ingests
mastication
propulsion
polysaccharides
The ________________ _________ is a physiological sphincter formed from slight thickening of ________ _______ _______
It is surrounded by ____________
Helps keep it ________ when food is not being swallowed
Properly functioning sphincter has ________ ______ on both sides to help protect the ___________ from the reflux of _________ ______
Gastroesophageal sphincter
circular smooth muscle
diaphragm
closed
mucous cells
esophagus
stomach acid
Three functions of the Stomach
1. ___________ through ___________
2. ___________ ____________
Mechanical actions of peristalsis break down stomach contents
3. ___________
Beginning of ________ digestion and main enzymatic breakdown
Propulsion
peristalsis
Mechanical breakdown
Digestion
protein
When the ___________ is empty it collapses inwards and throws its _______ and __________ into large, longitudinal folds called ______
stomach
mucosa
submucosa
rugae
In the stomach, ________ ____ secretes ____________ _____
Makes stomach extremely acidic, pH of 1.5~3.5
digestion of food
optimal activity of __________-digesting _______ enzyme
Kills _______
parietal cells
hydrochloric acid
digestion
protein
pepsin
bacteria
In the stomach, _________ _____ secretes __________ _______
Glycoprotein required for vitamin B12 absorption in small intestine
Absence of intrinsic factor leads to B12 deficiency and _________ __________
_________ in RBCs
parietal cells
intrinsic factor
pernicious anemia
decrease
Parietal cells are prong-shaped with dense ________ to increase _______ _______ _____
microvilli
secretion surface area
In the stomach, cuboidal ______ ______ produces ___________, the inactive form of pepsin that is activated in the presence of HCL
chief cells
pepsinogen
Presence of ________ catalyzes the conversion of ____________ into pepsin
___________ ___________ is limited only by amount of pepsinogen
pepsin
pepsinogen
positive feedback
In the stomach, cuboidal ______ _______ secrete ________ that account for 15% of GI lipolysis
chief cells
lipases
Mucosal Barrier
How the stomach protects itself from the high acidity
1. Thick coating of ______________-____ _______
builds up on the _________ ______
bicarbonate-rich mucus
stomach wall
Mucosal Barrier
How the stomach protects itself from the high acidity
2. The ____________ ______ of the ________ are joined by _________ ___________
Prevents ________ __________ from leaking into ____________ tissues
epithelial cells
mucosa
tight junctions
gastric juices
underlying
Mucosal Barrier
How the stomach protects itself from the high acidity
3. Damaged __________ __________ _______ are quickly __________ by undifferentiated ______ ________
Stomach surface epithelium of mucous cells is renewed every ____ to ____ days
epithelial mucosal cells
replaced
stem cells
3
6
______________
Mostly retroperitoneal
Curves around the head the pancreas
10 inches long
Duodenum
__________
Intraperitoneal
8 ft long
Extends from duodenum to ileum
Jejunum
___________
Intraperitoneal
12 ft long
Converges with large intestine at ileocecal valve
Ileum
what are the two substances required for proper digestion in the small intestine?
bile and pancreatic digestive enzymes
How the small intestine increases its surface area
1. _________ _______ are deep, permanent folds of the _______ and __________ that forces ________ to _______ spiral throughout the ________ for increased nutrient ____________ time
circular folds
mucosa
submucosa
chyme
slowly
lumen
absorption
How the small intestine increases its surface area
2. ____________ that are long and densely packed cytoplasmic extensions of the absorptive cells of the ________
They gives the mucosal surface a fuzzy appearance called the _______ _________
Plasma membranes of ___________ bear enzymes called ________ ________ _______ that completes the digestion of ___________ and __________ in the small intestine
microvilli
mucosa
brush border
microvilli
brush border enzymes
carbohydrates
proteins
How the small intestine increases its surface area
3. _____ that are the fingerlike projections of the _________
The core of each ______ contains a __________ ___ and a _________
Villi
mucosa
villus
capillary bed
lacteal
_________ are found in villi and are wide lymphatic capillaries that __________ absorbed ___ into the ___________
lacteals
transports
fat
bloodstream
__________ ________ are clusters of lymphoid follicles that protect against pathogens
peyer's patches
Brunner’s Glands / Duodenal Glands
Secretes an _________ mucus in the ___________ of the ____________
Helps ___________ acidic _______ moving in and from the stomach
alkaline
submucosa
duodenum
neutralize
chyme
Digestive roles of the liver
Produces 900 ml of ______ daily for export to the ____________
bile
duodenum
Metabolic Roles of the liver
1. Processes nutrient-laden _________ __________ delivered to it by digestive organs
Stores glucose as __________
Use amino acids to make ___________ ____________
venous blood
glycogen
plasma proteins
Metabolic Roles of the liver
2. Stores fat-soluble vitamins
Detoxification
Rids ________ of _________ by converting it into ______
blood
ammonia
urea
The __________________ stores bile that is not immediately needed for digestion and concentrates it by absorbing some of its water and ions
gallbladder
Pancreas ____________ functions
Pancreatic islets, scattered glands that produce insulin and glucagon
endocrine
Pancreas ______________ functions
Clusters of ________ ______ produces enzyme-rich pancreatic juice
Contains ______ that transports pancreatic juice
Epithelial cells of smallest ducts secrete water that make up the bulk of pancreatic juice and bicarbonate that makes the secretion __________ at a pH of 8
exocrine
acinar cells
ducts
alkaline
Main function of the large intestine
__________ the remaining _______ from indigestible food residues
________ the residues ____________
absorbs
water
stores
temporarily
________ ________
Consists of over a thousand different types of bacteria and accounts for a couple of pounds of our body weight
Helps us by __________ ______ from indigestible food and _____________ some ________
bacterial flora
recovering energy
synthesizing
vitamins
___________________
Gut bacteria ferment some indigestible carbohydrates and the mucin in gut mucus
Creates short-chain fatty acids for fuel by body cells
Fermentation
_______________ _________
B complex vitamins and some of the vitamin K the liver needs to produce clotting proteins are synthesized by gut bacteria
Vitamin Synthesis
what must open in order for bile and pancreatic juices to enter the small intestine?
hepatopancreatic sphincter