the _________ ________ is the innermost tunic it contains an ____________ and a _____________ epithelium that lines the lumen of all vessels
tunica intima
endothelium
simple squamous
the ______ _______ is the name for middle tunic it is the bulkiest layer in __________ and comprised of mostly circularly arranged ________ muscle cells and sheets of elastin, it is essential for regulating _________ _________ influencing blood ____ and blood ______
tunica media
arteries
smooth
vessel diameter
flow
pressure
the ___________ __________ is the name for the outermost tunic it is composed of loosely woven _________ _________ which protect and reinforces the vessel andA anchors it to nearby structures , it contains _______ fibers and ________ vessels
tunica externa
collagen fibers
nerve
lymphatic
the ______ ___________ is the system of tiny blood vessels in larger blood vessels on the tunica externa, it nourishes the ___________ tissue of the blood vessel wall
vasa vavorum
external
____________ are the smallest blood vessels
capillaries
capillaries have a thin ________ ________ surrounded by a __________ ___________
tunica intima
basement membrane
___________ have direct access to nearly every tissue in the body for __________ of gases, nutrients, hormones, etc
capillaries
exchange
there are contractile stem cells found on the outer surface of some capillaries called __________
pericytes
pericytes can generate ______ ________ , ______ tissue, ________ the capillary wall, and help ______________
new vessels
scar
stabilize
permeability
Gaps of unjoined membrane called _________ ________ allow passage of fluids and small solutes of capillaries
intercellular clefts
All three types of capillaries have _________ _________ that hold their ___________
cells together
tight junctions
endothelial
_____________ _____________ are most common in skin, muscles, lungs, and the CNS, they often have ___________ and ___________ _________ that ferry fluid across the endothelial cells
Most have _______________ unless in the brain to preserve the blood-brain barrier
Continuous capillaries
pericytes
Pinocytotic vessels
intercellular clefts
______________ _____________ appear in sites of active filtration like the kidney and in areas of __________ like small intestine, as well as areas of ___________ ____________ secretion they have tunnel-like holes called _____________ that increase permeability
Fenestrated Capillaries
absorption
endocrine hormone
fenestrations
___________ ___________ are most common in the liver, bone marrow, spleen, and adrenal medulla they have large ____________ ____________ and ________________ with few tight junctions as well as ______________ basement membranes which allow for large molecules and cells to pass through walls, ______ flows _______ through these channels
Sinusoidal Capillaries
intercellular clefts
fenestrations
incomplete
blood
slowly
Name 2 tissues that do not have capillary beds
1.
2.
cartilage
epithelium
When exercising blood is rerouted from __________ ________ to _________ _______ of _________ __________
digestive organs
capillary beds
skeletal muscle
After eating when digesting food, __________ of ________________ ________ receive breakdown products of digestion, their ________ pathways _____ between meals
capillaries
gastrointestinal organs
capillary
close
__________ __________ are arteries that are close to the heart like the ________, they
________ and ______ with ejection of blood from the heart
Elastic arteries
aorta
expand
recoil
______________ ___________ are distributing arteries they ___________ __________ to organs, they have the thickest ___________ _________ and are also active __________________
_____________ to organs
Muscular Arteries
distribute blood
tunica media
constrictors
______________ are the smallest type of arteries, when __________ ___________ constricts, the tissues served are largely bypassed. When they dilate, _________ __________ into the local __________ increases dramatically
Arterioles
arteriolar diameter
blood flow
capillaries
________________ refers to the flow of blood from the arteriole to a venule over a capillary bed
microcirculation
65% of blood supply in _____ as they are considered ________ _________
veins
blood reservoirs
anastomoses of the arteries is __________ _______________
arterial anastomoses
anastomoses of arteries and veins is _______________ _______________ and occurs over _____________ ______
where do they occur?
arteriovenous anastomoses
capillary beds
anastomoses of veins is ___________ ___________ and are ______ common
venous anastomoses
very
Blood moves from high pressure areas to low-pressure areas
blood pressure gradient
__________ __________ is the pressure the blood exerts against the inner walls of the blood vessels that, the force that keeps blood _____________
blood pressure
circulating
_________ are the smallest vein type and are very ______ allowing fluids and white blood cells pass through easy
venules
porous
____ usually have all 3 tunics and a thinner _______ _______ compared to arteries
veins
tunica media
veins possess a _______ ________ and _________ _________ to satisfy venous return despite the decrease in blood pressure compared to arteries
large lumen
venous valves
_________ __________ are specialized flat veins with thin walls like the coronary sinus
venous sinuses
the ___________ ___________ is the movement of the ___________ during inspiration that increases pressure on the abdomen resulting in an increased ________ __________
respiratory pump
diaphragm
venous return
the _____________ ___________ are skeletal muscle contractions that squeeze blood from the veins toward the heart increasing __________ _______
muscular pump
venous return
___________ control results in contraction of the ________ ________ in the ________ ________ increasing venous return
sympathetic
smooth muscle
tunica media
what are 4 short term neural mechanisms for maintaining blood pressure homeostasis?
1.
2.
3.
4.
vasomotor center
baroreceptor initiated reflex
chemoreceptor initiated reflex
higher brain centers
short term neural mechanisms for maintaining blood pressure
the ____________ center in the medulla utilizes ___________ control of blood vessel diameter to regulate _________ __________ meaning __________ are moderately contracted at a baseline
vasomotor
sympathetic
vasomotor tone
arterioles
short term neural mechanisms for maintaining blood pressure
_________________ -initiated reflex initiated by neural receptors in large ________ of the ______ and ______
baroreceptor
arteries
head
neck
short term neural mechanisms for maintaining blood pressure
____________-initiated reflexes initiated by a lack of ________ or increase in ___ or _________ ________ triggers the ___________ center
chemoreceptor
oxygen
pH
carbon dioxide
vasomotor
short term neural mechanisms for maintaining blood pressure
________ ________ _________ induce blood pressure regulation integrated in the _________ and controlled through the _____________
higher brain centers
medulla
hypothalamus
what are 4 short-term hormonal mechanisms for controlling blood pressure?
1.
2.
3.
4.
Adrenal medulla hormones
Atrial Natriuretic Peptide
Antidiuretic Hormone
Angiotensin ll
4 short-term hormonal mechanisms for controlling blood pressure
_____________ and _________________ are the adrenal medullary hormones that control blood pressure
epinephrine and norepinephrine
4 short-term hormonal mechanisms for controlling blood pressure
____________ ___________ _____________ is a hormone produced by the atria and lowers blood pressure
atrial natriuretic peptide
4 short-term hormonal mechanisms for controlling blood pressure
the hypothalamus stimulates kidneys to conserve water and lower blood pressure through __________ ___________
antidiuretic hormone
4 short-term hormonal mechanisms for controlling blood pressure
the _________ ___________ ____________ mechanism
renin-angiotensin-aldosterone
__________ ___________ is blood flow through tissues
tissue perfusion
____ ____________ occurs at the arteriole end of the capillary bed
net filtration
____ _____________ occurs at the venule end of the capillary bed
net reabsorption
What are the 3 sources of peripheral resistance?
1. blood _________
2. blood vessel ___________
3. blood vessel ______
viscosity
diameter
length
Thickness of blood is based on the number of ______________, if viscosity increases then ___________ __________ increases which then increases ________ ________ _________
erythrocytes
peripheral resistance
arterial blood pressure
if blood viscosity decreases then __________ __________ decreases which then decreases ___________ ________ _________
peripheral resistance
arterial blood pressure