c
What percentage of calcium is protein bound?
a) 20%
b) 50%
c) 40%
d)10%
d
What percentage of calcium is complexed/chelated?
a) 20%
b) 50%
c) 40%
d)10%
b
What percentage of calcium is ionized?
a) 20%
b) 50%
c) 40%
d)10%
PTH
-acts to breakdown bone and activate Vitamin D
increase calcium absorption from intestines & calcium conservation via kidneys; excrete phosphorous
What are the two functions of vitamin D?
thyroid; calcitonin
The ________ gland releases _______ when calcium levels are too high; stops bone breakdown
a
Calcium and _____ have a reciprocal relationship, as one goes up the other goes down.
a) phosphorus
b) magnesium
c) chloride
d) sulfur
thyroidectomy
-calcium moves from blood back into the bone.
arrhythmia, decreased heart contractility, hf, positive chvostek's sign, trousseau's sign
Signs and symptoms of hypocalcemia?
prolonged qt, elongation of ST segment, ventricular tachycardia
What are ECG changes associated with hypocalcemia?
magnesium
Low ____ levels may indicate hypocalcemia.
PTH
Decreased levels of ______ indicate hypoparathyroidism.
Total serum ca
- tests albumin levels and pH to determine that there isn't a deficiency in the protein binding of calcium.
b
What is the best treatment of hypocalcemia?
a) calcium gluconate PO
b) calcium gluconate IV
c) Mg replacement
d) vitamin D
ace inhibitors, thiazide diuretics
Which medications can cause hypercalcemia?
hyperparathyroidism, hyperthyroidism, hypophoshpatemia
What conditions can cause hypercalcemia?
short st & qt; prolonged PR interval
ECG in hypercalcemia?
Bisphosphates
-these medications inhibit bone resorption
pamidronate, etidronate
What medications are bisphosphates?
Plicamycin
-cytotoxic antibiotic that decreases bone resorption
calcitonin
-reduces bone resorption and increase bone deposition Ca2+ and phosphate
gallium nitrate
-inhibits bone resorption
d
Which medication increases urinary Ca & Phosphorus excretion?
a) gallium nitrate
b) pamidronate/etidronate
c) plicamycin
d) calcitonin
e) cortisone
f) hemodialysis
e
Which medication is comprised of steroids and competes with vitamin d for absorption in the small intestines?
a) gallium nitrate
b) pamidronate/etidronate
c) plicamycin
d) calcitonin
e) cortisone
f) hemodialysis
c
Which medication is indicated for neoplastic disorders?
a) gallium nitrate
b) pamidronate/etidronate
c) plicamycin
d) calcitonin
e) cortisone
f) hemodialysis
a,b
Which medication is used for malignant disease?
a) gallium nitrate
b) pamidronate/etidronate
c) plicamycin
d) calcitonin
e) cortisone
f) hemodialysis