2023-02-25T21:59:09+03:00[Europe/Moscow] en true <p>basolateral sodium-potassium pump</p>, <p>na+, glucose, galactose, phosphate, sulfate, amino acids</p>, <p>na+ enters cell &amp; h+ exits cell</p>, <p>CO2 from blood enters the basolateral membrane cells and reacts with H20; this reaction is mediated by carbonic anhydrase; carbonic acid is formed and breaks down; resulting in bicarbonate ion and h+ ion; h+ is secreted &amp; bicarbonate is reabsorbed </p>, <p>active</p>, <p>active or passive</p>, <p>HCO3 (bicarbonate) </p>, <p>electrolyte reabsorption leads to H2O reabsorption</p>, <p>isosmotic; hypo-osmotic </p>, <p>solute</p>, <p>a</p>, <p>b</p>, <p>proximal tubule, collecting ducts</p>, <p>loop of henle</p>, <p>osmolarity; medulla</p>, <p>b,d </p>, <p>d</p>, <p>b</p>, <p>sodium-glucose-cotransporter</p>, <p>high-flux low affinity</p>, <p>low-flux high affinity </p>, <p>TmG</p>, <p>glucose &gt; 200mg/dl</p>, <p>GFR, TmG, splay</p>, <p>decrease in glucose threshold </p>, <p>PAH</p>, <p>clearance = GFR</p>, <p>reabsorption</p>, <p> secretion</p>, <p>no filtration or 100% reabsorbed </p>, <p>acidosis; H-k-atpase</p>, <p>alkalosis; bicarbonate-cl exchanger</p> flashcards
Ch. 34 part 4. Proximal Tubule, loop of henle,

Ch. 34 part 4. Proximal Tubule, loop of henle,

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  • basolateral sodium-potassium pump

    The drive of sodium transport is accomplished via the ________.

  • na+, glucose, galactose, phosphate, sulfate, amino acids

    What are substances that enter the luminal side via symporter membrane proteins?

  • na+ enters cell & h+ exits cell

    What are substances that enter the luminal side via antiporter membrane proteins?

  • CO2 from blood enters the basolateral membrane cells and reacts with H20; this reaction is mediated by carbonic anhydrase; carbonic acid is formed and breaks down; resulting in bicarbonate ion and h+ ion; h+ is secreted & bicarbonate is reabsorbed

    Explain the reabsorption of HCO3-.

  • active

    Tubular secretion is a(n )_______ process.

  • active or passive

    Tubular reabsorption is a(n) _________ process.

  • HCO3 (bicarbonate)

    Reabsorption of ________ can alleviate metabolic acidosis.

  • electrolyte reabsorption leads to H2O reabsorption

    How does water reabsorption occur in the proximal tubule?

  • isosmotic; hypo-osmotic

    Fluid entering the loop of Henle is ______ and fluid leaving the loop of Henle is ______.

  • solute

    The loop of Henle primarily focuses on _________ reabsorption

  • a

    The descending limb of the loop of Henle is _________.

    a) water permeable

    b) water-impermeable

  • b

    The ascending limb of the loop of Henle is _________.

    a) water permeable

    b) water-impermeable

  • proximal tubule, collecting ducts

    Where does the reabsorption of urea occur?

  • loop of henle

    Where does the active secretion of urea occur?

  • osmolarity; medulla

    If the absorption of urea and water is stopped in the collecting duct, _________ of the ______ decreases and the concentration mechanisms collapse.

  • b,d

    Urea circulation is responsible for concentrating what substances in the urine?

    a) K+

    b)NaCl

    c) HCO3

    d) Creatinine

  • d

    Which region of the nephron has a specific k-transporter?

    a) proximal tubule

    b) collecting duct

    c) distal tubule

    d) loop of henle

  • b

    Glucose is reabsorbed 100% in the ______.

    a) bowman's capsule

    b) proximal tubule

    c) loop of henle

    d) distal tubule

    e) collecting duct

  • sodium-glucose-cotransporter

    Glucose reabsorption is accomplished via _______.

  • high-flux low affinity

    S1 segment =

  • low-flux high affinity

    S3 segment =

  • TmG

    -when the rate of filtered glucose reaches a constant maximal value

    -glucose carriers are all saturated

  • glucose > 200mg/dl

    When does TmG occur?

  • GFR, TmG, splay

    Glucose threshold depends on three factors; what are they?

  • decrease in glucose threshold

    Increase in splay = ?

  • PAH

    -an exogenous substance that is filtered and actively secreted such that it is almost completely extracted from the plasma in one pass through the kidney.

    -used to estimate renal plasma flow

  • clearance = GFR

    Clearance ratio = 1.0 ; what occurs

  • reabsorption

    Clearance ratio < 1; what occurs?

  • secretion

    Clearance ratio > 1; what occurs?

  • no filtration or 100% reabsorbed

    Clearance ratio = 0; what occurs?

  • acidosis; H-k-atpase

    Intercalated A cells respond to _________ via _________.

  • alkalosis; bicarbonate-cl exchanger

    Intercalated B cells respond to __________ via __________.