old age, racial/ethnic minority, exposure to certain chemicals/environmental conditions, low income or education
What are some sociodemographic factors associated with CKD?
poor glycemic control in diabetes, hypertension, uti, urinary stones, uto, neoplasia,
What are some clinical factors associated with CKD?
shape & position
What are the most common fetal anomalies in kidneys?
b
The failure of an organ to develop normally.
a) Agenesis
b) Dysgenesis
c) Neogenesis
d) hypoplasia
blood pressure checks & ultrasound
How do we monitor Dysgenesis?
low blood glucose or low sodium diet
What kind of diet do we recommend for children with Agenesis?
false; no treatment options
For infants and children with Agenesis, there are few treatment options when only one kidney is affected. True or false?
maintain fluid & electrolyte balance; correct acidity levels in blood
How do we treat Hypoplasia?
a
The complete failure of an organ to develop.
a) Agenesis
b) Dysgenesis
c) Neogenesis
d) hypoplasia
d
The failure of an organ to reach normal size.
a) Agenesis
b) Dysgenesis
c) Neogenesis
d) hypoplasia
low amount of amniotic fluid
What causes Potter Syndrome?
c
Besides the kidneys being underdeveloped in Potter Syndrome, what other organ is underdeveloped?
a) brain
b) heart
c) lungs
d) bladder
cystic renal dysplasia, obstructive uropathy, autosomal recessive polycystic disease, unilateral agenesis
What are causes of Neonatal renal failure in Potter Phenotype?
Cystic renal dysplasia
-enlarged kidney distorted by variably sized cysts that may involve one or both kidneys.
renal parenchymal malformation
What is the cause of Cystic Renal dysplasia?
Obstructive uropathy
–is a blockage that inhibits the flow of urine through its normal path (the urinary tract), including the kidneys, ureters, bladder, and urethra
kidney damage, kidney stones, and infection
Blockage of the urinary tract can lead to :
pain in the side, decreased or increased urine flow, urinating at night
Symptoms of obstructive uropathy?
Autosomal recessive polycystic disease
-a genetic disorder that causes both kidneys to have varying sized cysts.
a,d
What are signs of Potter Syndrome in babies?
a) kidney failure
b) high blood pressure
c) enlarged kidneys
d) breathing problems
e) microscopic blood in the urine
b, c
What are signs of Potter Syndrome in children older than 1?
a) kidney failure
b) high blood pressure
c) enlarged kidneys
d) breathing problems
hematouria, flank pain, high blood pressure, uti
What are signs of Potter syndrome in adults?
Unilateral agenesis
- a relatively uncommon condition
-it is the absence of one or both kidneys
c
What are the Prerenal sites susceptible to kidney disease?
a) tubules
b) renal medulla
c) glomerulus
d) ureter
e) bladder
a,b
What are the Intrarenal sites that are susceptible to kidney disease?
a) tubules
b) renal medulla
c) glomerulus
d) ureter
e) bladder
d,e
What are the Post-Renal sites that are susceptible to kidney disease?
a) tubules
b) renal medulla
c) glomerulus
d) ureter
e) bladder
inadequate renal blood flow
Pre-renal disease is caused by ?
nephron damage, ischemia
Intrarenal disease is caused by ?
malformations, obstruction, masses (cancer)
Post-Renal disease is caused by ?
Glomerulonephritis
-a group of diseases that injure the renal glomeruli
cause of acute kidney injury; account for 15% of ESRD
Glomerulopathies are an important:
primary glomerulopathy
-conditions where glomerular disease is the result of primary renal pathology
d
Which of the following is a Primary Glomerulopathy?
a) Diabetes mellitus
b) Vasculitis
c) Post-streptococcal glomerulonephritis
d) IgA nephropathy
vasculitis, post-streptococcal, diabetes mellitus
What are secondary glomerulopathies?
Secondary
-these are systemic disorders where part of the disease process involves injury to the renal glomeruli
Anti GBM disease
-circulating antibodies are directed to proteins on the basement membrane, which initiates a pro-inflammatory response.
a
Which pattern can cause proteinuria
a) Nephrotic pattern
b) Nephritic pattern
b
Which pattern can result in hematuria
a) Nephrotic pattern
b) Nephritic pattern
a
Which pattern rarely results in acute kidney injury?
a) Nephrotic pattern
b) Nephritic pattern
b
Which pattern can result in rapidly progressive glomerulonephritis?
a) Nephrotic pattern
b) Nephritic pattern
vasculitis, amyloidosis, post-streptococcal glomerulonephritis, diabetes mellitus
secondary causes of glomerulopathy?