Heart
-serves as pump that establishes the pressure gradient needed for blood to flow to tissues.
Blood
-transport medium within which materials being transported are dissolved or suspended.
capillaries
-connect tissue cells and directly serve cellular needs
Lumen
- the central blood-containing space surrounded by tunics
tunica interna (intima)
-endothelial layer that lines the lumen of all vessels
Tunica media
-smooth muscle and elastic fiber layer, regulated by sympathetic nervous system
Tunica externa
-collage fibers that protect and reinforce vessels
tunica media
Which tunic controls vasoconstriction & vasodilation of all the vessels?
Conducting arteries
-thick-walled arteries near the heart; aorta and its major branches
Muscular arteries (distributing)
-below elastic arteries; delivers blood to body organs
-thick tunica media with more smooth muscle and less elastic tissue
Conducting arteries
_____________ can withstand & smooth out large blood pressure fluctuations allowing blood to flow fairly continuously through body.
muscular
The _________ arteries are active in vasoconstriction
Arterioles
___________ control flow into capillary beds via vasodilation and constriction.
Continuous
_______ capillaries consist of skin and muscle; junctions between cells are not complete leaving areas for transport of fluid and small molecules.
Fenestrated
__________ capillaries are found in kidney, endocrine and intestine; similar to continuous but pores (fenestrations) allow passage of small molecules
Sinusoidal
_________ capillaries are found in bone; most porous with fewer tight junctions to allow passage of larger molecules.
vasomotor nerves, local chemical conditions, bypass, flood
Blood flow is regulated by __________ & _________, so it can either _________ or ________ the capillary bed.
Precapillary sphincter
-cuff of smooth muscle that surrounds each true capillary
-regulates blood flow into the capillary
venules
_______ are formed when capillary beds unite
2; smooth muscle
Large venules are composed of ______ layers of _________.
veins
-are formed when venules converge.
large-diameter lumens(offer little resistance to flow); valves (prevent backflow of blood)
What are the special adaptations of veins?
Systolic
________ results from blood forced into the arteries during ventricular systole.
Diastolic
_________ is the pressure in the arteries during ventricular diastole.
arterioles
Where does the steepest change in blood pressure occur?
-capillaries
-veins
-arterioles
-venules
aorta
Where is systemic pressure the highest?
Q= change in pressure/ resistance
Formula for law of Bulk Flow?
direct, change
For every increase or decrease in MAP(pressure change) there is a ______ change in ________.
inverse, flow
For every increase or decrease in resistance, there is a ________ change in ______.
Low MAP
hypotension
High MAP
hypertension
direct, flow
For every increase or decrease in tube radius there is a ________ change in _______.
inverse, flow
For every increase or decrease in tube length or viscocity there is a ________ change in _________.
elasticity, transmural pressure
What are the other factors that determine blood pressure?
elasticity/ distending pressure
inward pressure
transmural pressure
outward pressure
decrease
Increase in P will be offset by __________ in R
increase
Decrease in P will be offset by __________ in R