Cellular component
-living formed elements
Liquid component
-nonliving fluid element suspends cellular component
Hematocrit
-percentage of blood volume that consists of erythrocytes
Plasma
-55% of whole blood
-least dense component
Buffy coat
-leukocytes and platelets
-<1% of whole blood
albumins, globulins, fibrinogen
What are the proteins found in blood plasma?
Albumins
-plasma osmotic pressure and maintenance of blood volume
Globulins
-a globulin transports bilirubin and steroids
B globulin
-transports iron and copper
Y globulin
-makes up antibodies
RBCs, platelets, leukocytes
What are the components of the formed elements?
acidic dye
-eosin; stains pink
basic dye
-methylene blue; stains blue and purple
120 days
How long is the life span of RBC?
pelvis, skull, ribs, vertebrae, long bones
RBCs are manufactured continuously in bone marrow of _______, ________, ______, ________, and ends of _________
cytoplasm
___________ is packed with hemoglobin
reversibly
Hemoglobin _________ binds with oxygen
4
How many molecules of oxygen can hemoglobin transport?
globin, 2 alpha & 2 beta chains bound to heme group
Hemoglobin composition?
Diapedesis
the passage of leukocytes through the intact walls of the capillaries, typically accompanying inflammation.
ameoboid motion
How do leukocytes move once they are in the loose CT?
agranular
-lack granules and have a circular or indented nucleus
granular
-contain granules in cytoplasm and lobed nucleus
neutrophils, eosinophils, basophils
What are your granulocytes?
monocytes, macrophages
What are your agranulocytes?
signals more platelets to arrive, initiate inflammation, cause vasoconstriction
Functions of platelets:
neutrophils
-most abundant leukocyte
-destroys bacteria by phagocytosis
-granular
eosinophils
-turn off allergic responses and kill parasites
-granular
basophils
-release histamine and other mediators of inflammation
-granular
lymphocytes
-mount immune response by direct cell attack (T cells) or via antibodies (B cells)
-agranular
monocytes
-phagocytosis; develop into macrophages in tissues
lymphoid stem cells
-give rise to lymphocytes
myeloid stem cells
-give rise to all blood cells