Enzyme inhibitor
Directly or indirectly interferes with the functioning of the active site of an enzyme and so reduces its activity
how does increasing substrate concentration reduce the effect of the inhibitor
More substrate molecules present, greater the chance of binding to active sites, leaving fewer to the inhibitor. If inhibitor concentration is increased, it binds to more active sites and so the reaction is slower
Non-competitive
Affects bonds within the molecule which alters the overall shape of the enzyme, including its active site. As the inhibitor concentration increases, more enzymes are denatured and the rate of reaction and final mass of product decreases. Some bind reversibly, whilst others do so irreversibly
Potassium cyanide
Non-competitive enzyme inhibitor - inhibits the enzyme that produces ATP in the mitochondria. It does not bind permanently to the enzyme, making it known as a reversible, non-competitive inhibitor