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Antibiotics (Clinical Pearls)

Antibiotics (Clinical Pearls)

  • c

    Which drug is the DOC for MRSA and C. diff (PO only) ?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • c

    Which drug gives an accurate renal function assessment?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which is the DOC for tickborne diseases?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which interferes with oral contraceptives?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which of the following is considered to be the ONLY antibiotic class with no C.diff association?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which of the following has DDIs with divalent cations?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which is the DOC for C. acnes, A. baumannii?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • b

    Which is the DOC for Vancomycin-resistant gm (+) organisms?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • b

    Which of the following drugs requires calcium to be effective?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • b

    Which of the following drugs has DDI w/ statins?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • d

    Which of the following has DDIs with CYP3A4 & P-Gps?

    a) doxycycline

    b) daptomycin

    c) vancomycin

    d) azithromycin

    f) dalbavancin

  • a

    Which is the DOC for MAC prophylaxis?

    a) azithromycin

    b) erythromycin

    c) clarithromycin

    d) telithromycin

  • c

    Which is the DOC for MAC treatment?

    a) azithromycin

    b) erythromycin

    c) clarithromycin

    d) telithromycin

  • b

    Which is the DOC for prostatitis and B. anthracis?

    a) levofloxacin

    b) ciprofloxacin

    c) moxifloxacin

    d) gamifloxacin

  • b

    Which drug is considered last-line agents?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • b

    Which drug has DDIs with divalent cations?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • b

    Which drug has DDIs with warfarin?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • a

    Which drug has an extremely long half-life?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • a

    Which drug takes 30 min to 1-hr to infuse?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • c

    Which drug is a salvage therapy for Mycobacteria infections?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • c

    Which class is considered the up-and-coming DOC for MRSA pneumonia?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • c

    Which class is considered the DOC for Vancomycin-resistant gm (+) organisms?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • d

    Which belongs to a class that is considered a top 3 cause of C.diff?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • d

    Which is the class for toxin suppression in necrotizing infections?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • d

    Which has dose-dependent diarrhea?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • d

    Which drug class is known for poor adherence?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which do we avoid using when a patient is in their 1st trimester?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which has an unstable IV formulation?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which drug do we avoid if patient has sulfa allergy?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which of the following DOES NOT cover enterococci?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which class is the DOC for Toxoplasmosis prophylaxis?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which class is the DOC for Stenotrophomonas?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • e

    Which class is the DOC for Nocardia?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • f

    Which class is part of a salvage combo therapy for MDR Gm (-) infections?

    a) Lipoglycopeptides

    b) Fluoroquinolones

    c) Oxazolidnones

    d) Lincosamides

    e) Folate antagonist

    f) Polymyxin

  • 2

    Polymyxin ____ is a prodrug.

    1) b

    2) e

  • f

    Which class has the potential to be a STI treatment alternative?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • e

    Which class is used in patients with type 1 hypersensitivity reactions to pens and cephs?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • d

    Which class is safe in children and pregnancy?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • d

    Which class only requires a one-time dose?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • d

    Which class's IV formulation is approved in the EU only?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • c

    Which class is the DOC for Trichomonas, B. Fragilis?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • c

    Which class do we avoid in the 1st trimester?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • c

    Which class has an overstated disulfiram-like reaction?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • b

    Which has no systemic efficacy (including the kidneys)?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • b

    Which CANNOT be used if CrCl < 30 mL/min?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • b

    Which requires we check the patient's G6PD status prior to long-term use?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • a

    Which requires Therapeutic-Dose Monitoring? (TDM)

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • a

    Which is often used as synergy or combination therapy?

    a) aminoglycosides

    b) nitrofurans

    c) nitroimidazole

    d) fosfomycin

    e) monobactam

    f) Pleuromutilins

  • c

    Which is second line for TB and Nocardia?

    a) gentamicin

    b) tobramycin

    c) amikacin

    d) plazomicin

  • penicillin

    What is the DOC for syphilis?

  • ampicillin, amoxicillin

    What is the DOC for E. Faecalis ? (2)

  • nafcillin, oxacillin, cefazolin

    What is the DOC for MSSA? (3)

  • carbapenems

    What is the DOC for multidrug-resistant organisms?