2017-08-01T17:45:00+03:00[Europe/Moscow] en true RG7795, Ledipasvir/sofosbuvir, Ribavirin, Filibuvir, Sofosbuvir, Miravirsen, Dasabuvir, Elbasvir, Elbasvir/grazoprevir, Ombitasvir, Ombitasvir/paritaprevir/ritonavir, Velpatasvir, Velpatasvir/sofosbuvir, Setrobuvir, Beclabuvir, Ravidasvir, Sofosbuvir/daclatasvir flashcards
Anti-hepatitis C agents

Anti-hepatitis C agents

  • RG7795
    RG7795 (ANA773 previously) is an experimental oral prodrug of isatoribine developed by Anadys Pharmaceuticals which forms an active metabolite that is an agonist for TLR7.
  • Ledipasvir/sofosbuvir
    Ledipasvir/sofosbuvir (trade name Harvoni) is a two-drug combination for the treatment of hepatitis C.
  • Ribavirin
    Ribavirin is an anti-viral drug used for severe RSV infection; hepatitis C infection, including if persistent, and often in combination with peginterferon alfa-2b or peginterferon alfa-2a; as well as some other viral infections.
  • Filibuvir
    Filibuvir (also known as PF-00868554, PF-868554) was a non-nucleoside orally available NS5B inhibitor developed by Pfizer for the treatment of hepatitis C.
  • Sofosbuvir
    Sofosbuvir (brand name Sovaldi) is a nucleotide analog used in combination with other drugs for the treatment of hepatitis C virus (HCV) infection.
  • Miravirsen
    Miravirsen (INN; codenamed SPC3649) is an experimental drug for the treatment of hepatitis C, being developed by Santaris Pharma.
  • Dasabuvir
    Dasabuvir (trade name Exviera in Europe) is an antiviral drug for the treatment of hepatitis C virus (HCV) infection.
  • Elbasvir
    Elbasvir (MK-8742) is a drug approved (FDA Jan 2016) for the treatment of hepatitis C.
  • Elbasvir/grazoprevir
    Elbasvir/grazoprevir (trade name Zepatier ZEP-ah-teer) is a fixed-dose two drug combination for the treatment of hepatitis C, containing 50 mg elbasvir (a hepatitis C virus NS5A inhibitor) and 100 mg grazoprevir (an NS3/4A protease inhibitor).
  • Ombitasvir
    Ombitasvir is an antiviral drug for the treatment of hepatitis C virus (HCV) infection.
  • Ombitasvir/paritaprevir/ritonavir
    A combination product of three antiviral drugs ombitasvir, paritaprevir and ritonavir is used with the drug dasabuvir in the treatment of hepatitis C Virus Genotype 1a or 1b (HCV GT1a or GT1b).
  • Velpatasvir
    Velpatasvir is an inhibitor of NS5A used together with sofosbuvir in the treatment of hepatitis C infection of all six major genotypes.
  • Velpatasvir/sofosbuvir
    Velpatasvir/sofosbuvir (trade name Epclusa) is a two-drug combination for the treatment of hepatitis C.
  • Setrobuvir
    Setrobuvir (INN, USAN, also known as ANA-598) was an experimental drug candidate for the treatment of hepatitis C.
  • Beclabuvir
    Beclabuvir (BMS-791325) is an antiviral drug for the treatment of hepatitis C virus (HCV) infection currently in clinical trials.
  • Ravidasvir
    Ravidasvir (PPI-668) is an investigational NS5A inhibitor in clinical trials for chronic hepatitis C genotype 4.
  • Sofosbuvir/daclatasvir
    Daclatasvir/sofosbuvir (trade name Darvoni) is a two-drug combination for the treatment of hepatitis C.