2023-11-06T05:22:10+03:00[Europe/Moscow] en true <p>increased no. of RBCs/ hemoglobin; decreases likelihood of blood transfusions </p>, <p>Hgb &lt; 10g/dL</p>, <p>Hgb 9-10 g/dL </p>, <p>&gt;11.5 g/dL</p>, <p>hypertension, infusion reaction, PRCA </p>, <p>patient on ESA &gt; 8 weeks + rapid drop in Hgb w low reticulocytes </p>, <p>1-2 g/dL per month </p>, <p>no sooner than every 4 weeks; may increase dose by 25% if Hgb doesn't increase after 1 month </p>, <p>reduce by 25% if Hgb increases &gt; 1 g/dL in 2 weeks; if HgB &gt; 11.5 g/dL </p>, <p>iron, B12, folate deficiency; chronic bleeding, ACEi/ARB</p>, <p>anemia of CKD + dialysis </p>, <p>iron deficiency </p> flashcards
Anemia Therapeutics Pt. 2

Anemia Therapeutics Pt. 2

Customize
collection saved
Share
Long Term Learning Spaced Repetition
Add to Long Term Learning Desk
Fast learning Repeat this set of flashcards
Preview Test Spell
Play
Match
Review

  • increased no. of RBCs/ hemoglobin; decreases likelihood of blood transfusions

    What are the advantages of ESAs? (2)

  • Hgb < 10g/dL

    When do we initiate an ESA in Non-Dialysis patients?

  • Hgb 9-10 g/dL

    When do we initiate an ESA in HD patients?

  • >11.5 g/dL

    What hemoglobin level do we have to avoid with ESAs?

  • hypertension, infusion reaction, PRCA

    What are AE's of ESAs? (3)

  • patient on ESA > 8 weeks + rapid drop in Hgb w low reticulocytes

    When do we suspect a PRCA reaction?

  • 1-2 g/dL per month

    What is our goal rate of for hemoglobin increase?

  • no sooner than every 4 weeks; may increase dose by 25% if Hgb doesn't increase after 1 month

    When can we increase the dose of an ESA?

  • reduce by 25% if Hgb increases > 1 g/dL in 2 weeks; if HgB > 11.5 g/dL

    When do we reduce the dose of an ESA? (2)

  • iron, B12, folate deficiency; chronic bleeding, ACEi/ARB

    What can cause hyporesponsiveness to ESAs? (5)

  • anemia of CKD + dialysis

    What is the indication for Daprodustat?

  • iron deficiency

    What should be treated before starting an ESA?