2017-07-27T18:28:45+03:00[Europe/Moscow] en true VX (nerve agent), Distigmine, Diazinon, Tetrahydrocannabinol, Rivastigmine, Ipidacrine, Ambenonium chloride, Tabun (nerve agent), Donepezil, Harmaline, Neostigmine, Pyridostigmine, Physostigmine, Soman, Galantamine, Metrifonate, Parathion, Huperzine A, Ungiminorine, Cyclanoline, Echothiophate, Taspine, Acotiamide, Edrophonium, Itopride, Onchidal, Coronaridine, Alpha-Viniferin, Kobophenol A, Ungeremine, Ladostigil, Diisopropyl fluorophosphate, Bulbocapnine, Conodurine, Corydaline, Corynoline, Affinine, Arisugacin A flashcards
Acetylcholinesterase inhibitors

Acetylcholinesterase inhibitors

  • VX (nerve agent)
    Venomous Agent X, aka VX (IUPAC name O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) is an extremely toxic substance that has no known uses except in chemical warfare as a nerve agent.
  • Distigmine
    Distigmine (as distigmine bromide) is a parasympathomimetic.
  • Diazinon
    Diazinon (IUPAC name: O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta).
  • Tetrahydrocannabinol
    Tetrahydrocannabinol (THC, dronabinol by INN), or more precisely its main isomer (−)-trans-Δ9-tetrahydrocannabinol, is the principal psychoactive constituent (or cannabinoid) of cannabis.
  • Rivastigmine
    Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
  • Ipidacrine
    Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation.
  • Ambenonium chloride
    Ambenonium (as ambenonium dichloride, trade name Mytelase) is a cholinesterase inhibitor used in the management of myasthenia gravis.
  • Tabun (nerve agent)
    Tabun or GA is an extremely toxic chemical substance.
  • Donepezil
    Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease.
  • Harmaline
    Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines.
  • Neostigmine
    Neostigmine (Prostigmin, Vagostigmin) (from Greek neos, meaning "new," and "-stigmine," in reference to its parent molecule, physostigmine, on which it is based) is a parasympathomimetic compound that acts as a reversible acetylcholinesterase inhibitor.
  • Pyridostigmine
    Pyridostigmine is a parasympathomimetic and a reversible cholinesterase inhibitor.
  • Physostigmine
    Physostigmine (also known as eserine from éséré, the West African name for the Calabar bean) is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor.
  • Soman
    Soman, or GD (systematic name: O-Pinacolyl methylphosphonofluoridate), is an extremely toxic chemical substance.
  • Galantamine
    Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin.
  • Metrifonate
    Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor.
  • Parathion
    Parathion, also called parathion-ethyl or diethyl parathion and locally known as "Folidol", is an organophosphate compound possessing a organothiophosphate group.
  • Huperzine A
    Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H.
  • Ungiminorine
    Ungiminorine is an acetylcholinesterase inhibitor isolated from Narcissus.
  • Cyclanoline
    Cyclanoline is an acetylcholinesterase inhibitor isolated from Stephania venosa tuber.
  • Echothiophate
    Echothiophate (Phospholine) is an irreversible acetylcholinesterase inhibitor.
  • Taspine
    Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor and cicatrizant.
  • Acotiamide
    Acotiamide (YM-443, Z-338) is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.
  • Edrophonium
    Edrophonium is a readily reversible acetylcholinesterase inhibitor.
  • Itopride
    Itopride (INN) (brand name Ganaton) is a prokinetic benzamide derivative unlike metoclopramide or domperidone.
  • Onchidal
    Onchidal is a naturally occurring toxin produced as a defensive secretion by the mollusc Onchidella binneyi and several other related species in Onchidella,a genus of small, air-breathing sea slugs.
  • Coronaridine
    Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species,including Tabernaemontana divaricata for which (under the now obsolete synonym Ervatamia coronaria) it was named.
  • Alpha-Viniferin
    α-Viniferin is a stilbene trimer.
  • Kobophenol A
    Kobophenol A is a stilbenoid.
  • Ungeremine
    Ungeremine is an acetylcholinesterase inhibitor isolated from Nerine bowdenii.
  • Ladostigil
    Ladostigil (TV-3,326) is a novel neuroprotective agent being investigated for the treatment of neurodegenerative disorders like Alzheimer's disease, Lewy body disease, and Parkinson's disease.
  • Diisopropyl fluorophosphate
    Diisopropyl fluorophosphate (DFP, DIFP, diisopropyl phosphorofluoridate) is an oily, colorless liquid with the chemical formula C6H14FO3P.
  • Bulbocapnine
    Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle.
  • Conodurine
    Conodurine is an acetylcholinesterase inhibitor and butyrylcholinesterase inhibitor isolated from Tabernaemontana.
  • Corydaline
    Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
  • Corynoline
    Corynoline is an acetylcholinesterase inhibitor isolated from Corydalis incisa.
  • Affinine
    Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the Tabernaemontana genus.
  • Arisugacin A
    Arisugacin A is an orally-active acetylcholinesterase inhibitor.