2017-07-29T11:14:40+03:00[Europe/Moscow] en true Tabun (nerve agent), Tetrahydrocannabinol, Soman, Diazinon, Rivastigmine, Parathion, Donepezil, Harmaline, Sarin, VX (nerve agent), Metrifonate, Diisopropyl fluorophosphate, Bulbocapnine, Edrophonium, Acotiamide, Alpha-Viniferin, Ungeremine, Itopride, Kobophenol A, Echothiophate, Neostigmine, Physostigmine, Galantamine, Pyridostigmine, Taspine, Onchidal, Ipidacrine, Affinine, Arisugacin A, Cyclanoline, Corynoline, Corydaline, Conodurine, Ungiminorine, Ladostigil, Ambenonium chloride, Distigmine, Huperzine A, Coronaridine flashcards
Acetylcholinesterase inhibitors

Acetylcholinesterase inhibitors

  • Tabun (nerve agent)
    Tabun or GA is an extremely toxic chemical substance.
  • Tetrahydrocannabinol
    Tetrahydrocannabinol (THC, dronabinol by INN), or more precisely its main isomer (−)-trans-Δ9-tetrahydrocannabinol, is the principal psychoactive constituent (or cannabinoid) of cannabis.
  • Soman
    Soman, or GD (systematic name: O-Pinacolyl methylphosphonofluoridate), is an extremely toxic chemical substance.
  • Diazinon
    Diazinon (IUPAC name: O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta).
  • Rivastigmine
    Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
  • Parathion
    Parathion, also called parathion-ethyl or diethyl parathion and locally known as "Folidol", is an organophosphate compound possessing a organothiophosphate group.
  • Donepezil
    Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease.
  • Harmaline
    Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines.
  • Sarin
    Sarin, or GB (G-series, 'B'), is a colorless, odorless liquid, used as a chemical weapon owing to its extreme potency as a nerve agent.
  • VX (nerve agent)
    Venomous Agent X, aka VX (IUPAC name O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) is an extremely toxic substance that has no known uses except in chemical warfare as a nerve agent.
  • Metrifonate
    Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor.
  • Diisopropyl fluorophosphate
    Diisopropyl fluorophosphate (DFP, DIFP, diisopropyl phosphorofluoridate) is an oily, colorless liquid with the chemical formula C6H14FO3P.
  • Bulbocapnine
    Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle.
  • Edrophonium
    Edrophonium is a readily reversible acetylcholinesterase inhibitor.
  • Acotiamide
    Acotiamide (YM-443, Z-338) is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.
  • Alpha-Viniferin
    α-Viniferin is a stilbene trimer.
  • Ungeremine
    Ungeremine is an acetylcholinesterase inhibitor isolated from Nerine bowdenii.
  • Itopride
    Itopride (INN) (brand name Ganaton) is a prokinetic benzamide derivative unlike metoclopramide or domperidone.
  • Kobophenol A
    Kobophenol A is a stilbenoid.
  • Echothiophate
    Echothiophate (Phospholine) is an irreversible acetylcholinesterase inhibitor.
  • Neostigmine
    Neostigmine (Prostigmin, Vagostigmin) (from Greek neos, meaning "new," and "-stigmine," in reference to its parent molecule, physostigmine, on which it is based) is a parasympathomimetic compound that acts as a reversible acetylcholinesterase inhibitor.
  • Physostigmine
    Physostigmine (also known as eserine from éséré, the West African name for the Calabar bean) is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor.
  • Galantamine
    Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin.
  • Pyridostigmine
    Pyridostigmine is a parasympathomimetic and a reversible cholinesterase inhibitor.
  • Taspine
    Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor and cicatrizant.
  • Onchidal
    Onchidal is a naturally occurring toxin produced as a defensive secretion by the mollusc Onchidella binneyi and several other related species in Onchidella,a genus of small, air-breathing sea slugs.
  • Ipidacrine
    Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation.
  • Affinine
    Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the Tabernaemontana genus.
  • Arisugacin A
    Arisugacin A is an orally-active acetylcholinesterase inhibitor.
  • Cyclanoline
    Cyclanoline is an acetylcholinesterase inhibitor isolated from Stephania venosa tuber.
  • Corynoline
    Corynoline is an acetylcholinesterase inhibitor isolated from Corydalis incisa.
  • Corydaline
    Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
  • Conodurine
    Conodurine is an acetylcholinesterase inhibitor and butyrylcholinesterase inhibitor isolated from Tabernaemontana.
  • Ungiminorine
    Ungiminorine is an acetylcholinesterase inhibitor isolated from Narcissus.
  • Ladostigil
    Ladostigil (TV-3,326) is a novel neuroprotective agent being investigated for the treatment of neurodegenerative disorders like Alzheimer's disease, Lewy body disease, and Parkinson's disease.
  • Ambenonium chloride
    Ambenonium (as ambenonium dichloride, trade name Mytelase) is a cholinesterase inhibitor used in the management of myasthenia gravis.
  • Distigmine
    Distigmine (as distigmine bromide) is a parasympathomimetic.
  • Huperzine A
    Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H.
  • Coronaridine
    Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species,including Tabernaemontana divaricata for which (under the now obsolete synonym Ervatamia coronaria) it was named.