Flashcards: Thyroid

A goitre (British English) or goiter (American English) (from the Latin gutteria, struma) is a swelling of the neck or larynx resulting from enlargement of the thyroid gland (thyromegaly), associated with a thyroid gland that is not functioning properly.

Thyroid peroxidase or thyroperoxidase (TPO) is an enzyme expressed mainly in the thyroid where it is secreted into colloid.

The superior thyroid artery arises from the external carotid artery just below the level of the greater cornu of the hyoid bone and ends in the thyroid gland.

Postpartum thyroiditis is a phenomenon observed following pregnancy and may involve hyperthyroidism, hypothyroidism or the two sequentially.

The thyroid gland, or simply the thyroid /ˈθaɪrɔɪd/, is an endocrine gland in the throat, and consists of two connected lobes.

Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF) or thyroliberin, is a releasing hormone, produced by the hypothalamus, that stimulates the release of thyrotropin (thyroid-stimulating hormone or TSH) and prolactin from the anterior pituitary.

Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is an autoimmune disease in which the thyroid gland is gradually destroyed.

Triiodothyronine, also known as T3, is a thyroid hormone.

Thyroid storm or thyrotoxic crisis is a rare but severe and potentially life-threatening complication of hyperthyroidism (overactivity of the thyroid gland).

Acute infectious thyroiditis (AIT) also known as suppurative thyroiditis, microbial inflammatory thyroiditis, pyrogenic thyroiditis and bacterial thyroiditis.

Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormone by the thyroid gland.

(This article is about levothyroxine as a pharmaceutical drug. For its role as a hormone, see Thyroid hormone.) Levothyroxine, also known as L-thyroxine, is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland.

Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.

The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin") and stimulates the production of thyroxine (T4) and triiodothyronine (T3).

Follicular cells (also called thyroid epithelial cells or thyrocytes) are cells in the thyroid gland that are responsible for the production and secretion of thyroid hormones thyroxine (T4) and triiodothyronine (T3).

Thyroiditis is the inflammation of the thyroid gland.

De Quervain's thyroiditis, can also be known as subacute granulomatous thyroiditis or giant cell thyroiditis.

Subacute thyroiditis is a form of thyroiditis that can be a cause of both thyrotoxicosis and hypothyroidism.

Thyroid dysgenesis or thyroid agenesis is a cause of congenital hypothyroidism where the thyroid is missing, ectopic, or severely underdeveloped.

3,5-Diiodothyronine (3,5-T2) is an active thyroid hormone within the class of iodothyronines.

Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

3,3',5-Triiodothyronamine is a thyronamine.

3,3'-Diiodothyronine, also known as 3,3'-T2, is a metabolite of thyroid hormone.

Parafollicular cells (also called C cells) are neuroendocrine cells in the thyroid which primary function is to secrete calcitonin.

Desiccated thyroid or thyroid extract refers to porcine or bovine thyroid glands, dried and powdered for therapeutic use.

The inferior thyroid artery is an artery in the neck.

The thyroid ima artery (thyroidea ima artery, arteria thyreoidea ima, thyroid artery of Neubauer or the lowest thyroid artery) is an artery of the head and neck.

Liothyronine is a synthetic form of thyroid hormone (T3) used to treat hypothyroidism and myxedema coma.

The superior thyroid vein begins in the substance and on the surface of the thyroid gland, by tributaries corresponding with the branches of the superior thyroid artery, and ends in the upper part of the internal jugular vein.

The thyroid pouch or thyroid diverticulum is the embryological structure of the second pharyngeal arch from which thyroid follicular cells derive.

Graves' ophthalmopathy (also known as thyroid eye disease (TED), dysthyroid/thyroid-associated orbitopathy (TAO), Graves' orbitopathy) is an autoimmune inflammatory disorder affecting the orbit around the eye, characterized by upper eyelid retraction, lid lag, swelling, redness (erythema), conjunctivitis, and bulging eyes (exopthalmos).

Pretibial myxedema (myxoedema (UK), also known as Graves' dermopathy, thyroid dermopathy, Jadassohn-Dösseker disease or Myxoedema tuberosum) is an infiltrative dermopathy, resulting as a rare complication of Graves' disease, with an incidence rate of about 1-5% in patients.

3-Iodothyronamine (T1AM) is an endogenous thyronamine.

o-Phenyl-3-iodotyramine (o-PIT) is a drug which acts as a selective agonist for the trace amine-associated receptor 1.

(Not to be confused with Thyroxine-binding globulin, a carrier protein responsible for carrying the thyroid hormones in the blood.) Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland.

Dextrothyroxine (trade name Choloxin) saw research as a cholesterol-lowering drug but was pulled due to cardiac side-effects.

Zuckerkandl's tubercle is a pyramidal extension of the thyroid gland, present at the most posterior side of each lobe.

Diiodothyronine may refer to: * 3,3'-Diiodothyronine (3,3'-T2) * 3,5-Diiodothyronine (3,5-T2)

Deiodinase (or iodide peroxidase or "Monodeiodinase") is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones.

Liotrix is a 4:1 mixture of thyroxine (T4) and triiodothyronine (T3) made synthetically.

Reverse triiodothyronine (3,3’,5’-triiodothyronine, reverse T3, or rT3) is an isomer of triiodothyronine (3,5,3’ triiodothyronine, T3).

The inferior thyroid veins appear two, frequently three or four, in number, and arise in the venous plexus on the thyroid gland, communicating with the middle and superior thyroid veins.