Flashcards: Solute carrier family

The sodium-calcium exchanger (often denoted Na+/Ca2+ exchanger, NCX, or exchange protein) is an antiporter membrane protein that removes calcium from cells.

GLUT8 also known as SLC2A8 is the eighth member of glucose transporter superfamily.

The Na-K-Cl cotransporter (NKCC) is a protein that aids in the active transport of sodium, potassium, and chloride into and out of cells.

Carnitine-acylcarnitine translocase is responsible for transporting both carnitine-fatty acid complexes and carnitine across the inner mitochondrial membrane.

Multi-antimicrobial extrusion protein (MATE) also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton antiporters.

Band 3 anion transport protein, also known as anion exchanger 1 (AE1) or band 3 or solute carrier family 4 member 1 (SLC4A1), is a protein that is encoded by the SLC4A1 gene in humans.

Ornithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle.

Potassium-dependent sodium-calcium exchanger also known as solute carrier family 24 (SLC24) is a type of sodium-calcium exchanger that requires potassium to function.

Citrin also known as solute carrier family 25, member 13 (citrin) or SLC25A13 is a protein which in humans is encoded by the SLC25A13 gene.

Solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 also known as SLC7A9 is a protein which in humans is encoded by the SLC7A9 gene.

Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocator, exports ATP from the mitochondrial matrix and imports ADP into the matrix.

An organic anion-transporting polypeptide (OATP) is a membrane transport protein or 'transporter' that mediates the transport of mainly organic anions across the cell membrane.

An amino acid transporter is a membrane transport protein that transports amino acids.

SLC39A4 is a transmembrane protein associated with acrodermatitis enteropathica.

Mitochondrial carriers are proteins from a solute carrier family which transfer molecules across the membranes of the mitochondria.

Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST).

Ammonia transporters (TC# 1.A.11) are structurally related membrane transport proteins called Amt proteins (ammonia transporters) in bacteria and plants, methylammonium/ammonium permeases (MEPs) in yeast, or Rhesus (Rh) proteins in chordates.

Sodium sulfate symporters are integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions.

CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1).

The amino acid-polyamine-organocation (APC) superfamily is the second largest superfamily of secondary carriers currently known.

The anion exchanger family (TC# 2.A.31) is a member of the large APC superfamily of secondary carriers.

Homologues of ArsB are found in Gram-negative and Gram-positive bacteria as well as cyanobacteria.

The cadmium resistance (CadD) protein family (TC# 2.A.77) belongs to the Lysine exporter (LysE) superfamily.

Members of the divalent anion:Na+ symporter (DASS) family (TC# 2.A.47) are found in Gram-negative bacteria, cyanobacteria, archaea, plant chloroplasts, yeast and animals.

The gluconate:H+ symporter (GntP) family (TC# 2.A.8) is a family of transport proteins belonging to the ion transporter (IT) superfamily.

The resistance to homoserine/threonine (RhtB) family (TC# 2.A.76) belongs to the lysine exporter (LysE) superfamily of transporters.

The ion transporter (IT) superfamily is made up of secondary carriers specific for cationic and anionic compounds.

The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily.

The Lysine Exporter (LysE) Superfamily of integral membrane transport proteins was named based on the early discovery of the LysE carrier protein of Corynebacterium glutamicum (TC# 2.A.75.1.1), a Gram-positive bacterium, and its related counterparts.

The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) flippase superfamily (TC# 2.A.66) is a group of integral membrane protein families.

The Manganese (Mn2+) Exporter (MntP) Family (TC# 2.A.107) is a member of the Lysine Exporter (LysE) Superfamily.

The potassium (K+) uptake permease (KUP) family (TC# 2.A.72) is a member of the APC superfamily of secondary carriers.

The SWEET family, also known as the PQ-loop, Saliva or MtN3 family (TC# 2.A.123), is a family of sugar transporters and a member of the TOG superfamily.