1.5x SCR; U.O< 0.5ml x 6hr
AKIN Stage 1 =
2 x SCr; U.O. < 0.5ml x 12 hr
AKIN Stage 2 =
3 x SCr; U.O < 0.5 ml x 14 hr or Anuria x 12 hr
AKIN stage 3=
risk, injury, failure, loss, ESKD
What does RIFLE stand for?
cisplatin, amphotericin B, aminoglycosides
What are the main drugs involved in Acute Tubular Necrosis? (3)
antimicrobials, NSAIDs, PPI
What are the main drugs involved in Nephritis? (3)
b
Which has its results in mL/min?
a) MDRD
b) Cockcroft-Gault
c) CKD-Epi
d) Schwartz
b
Which is the ONLY ONE to estimate CrCl?
a) MDRD
b) Cockcroft-Gault
c) CKD-Epi
d) Schwartz
IBW + 0.4(ABW-IBW)
Adjusted BW formula?
Actual body weight; adjusted body weight
If a patient is underweight, we use _________. If a patient is
overweight/obese we use _________ in Cockcroft-Gault.
SCr, age, gender, if patient is AA
What variables do we need for MDRD? (4)
d
Which one is for pediatrics?
a) MDRD
b) Cockcroft-Gault
c) CKD-Epi
d) Schwartz
d
Which one uses a K factor?
a) MDRD
b) Cockcroft-Gault
c) CKD-Epi
d) Schwartz
mindikoglu, grail, royal free hospital
What are the renal calculations for a patient with Liver Disease? (3)
Jelliffe, Chiou, Brater
What are the renal calculations for a patient with Unstable Renal Function? (3)
less dialyzable
A drug with a large Volume of Distribution will be ___________.
Cl= Kel x Vd
Formula for Clearance?
Qp x (Ap-Vp)/Ap
Dialysis Clearance =
cystatin is produced in all nucleated cells
How does Cystatin differ from Creatinine?
bedside Schwartz has no K factor
What is the difference between Schwartz and Bedside Schwartz?
(weight (lbs)/ height^2 (in)) x 703
BMI formula?
< 18.5
Underweight BMI =?
>= 25
Overweight BMI = ?
b
Which is NOT normalized for BSA?
a) MDRD
b) Cockcroft-Gault
c) CKD-Epi
d) Schwartz
square root: height (cm) x weight (kg)/ 3600
BSA formula ?
how many times a patient has been pregnant
Gravida =
how many live-births
Parity =
overestimates GFR due to decreased creatine production
Why do we use different formulas for Liver Disease?
age, gender, SCr
What are the variables for CKD-EPI Refit 2021?
false; made for monitoring progression of CKD
GFR was designed to dose renally-eliminated drugs? T/F?
Cockcroft-gault estimate
eCLcr =
MDRD or CKD-EPI
eGFR =