c
Which is a reversible inhibitor?
a) rasagiline
b) selegiline
c) safinamide
b
Which is best for younger patients in early/mild PD?
a) rasagiline
b) selegiline
c) safinamide
c
Which is NOT effective as a monotherapy?
a) rasagiline
b) selegiline
c) safinamide
a
Which is the most potent?
a) rasagiline
b) selegiline
c) safinamide
meperidine, methadone, st.john's wort, Robitussin, tramadol, other MAOi, cyclobenzaprine
Which drugs do we avoid with MAO-B inhibitors? (7)
c
Which ONLY inhibits peripheral COMT?
a) Opicapone
b) Tolcapone
c) Entacapone
b
Which has a BBW for hepatotoxicity?
a) Opicapone
b) Tolcapone
c) Entacapone
patients who have not responded to other Tx's
When do we use Tolcapone?
c
Which is available in triple combination?
a) Opicapone
b) Tolcapone
c) Entacapone
GI, dyskinesia, arrhythmias, mental AEs similar to levodopa
What are the AE's of DRAs? (4)
a
Which is an agonist of D3, D2, and D1?
a) Rotigotine
b) Pramipexole
c) Ropinirole
d) Apomorphine