inhibit cardiac beta-adrenergic activation of adenylate cyclase; decreasing cAMP and ca++ influx
MOA of BBs?
decrease hr, suppress abnormal pacemakers, slow ventricular response in atrial arrhythmias
How do BBs affect the autorhythmic cells? (3)
increase; refractory period
BBs have a class effect involving the _______ in the ________
between action potentials.
a,d
Which BBs are used as MI prophylactics?
a) propranolol
b) esmolol
c) sotalol
d) atenolol
b
Which BBs are short-acting and used for surgery?
c
Which BB has class 3 action?
fatigue, bronchospasm, hypotension, ed, depression
AE's of BBs? (5)