heavy proteinuria, edema, hypoalbuminemia, hyperlipidemia, hypercoagulable state
What are the most common symptoms of Nephrotic Syndrome? (5)
structural changes; glomerular injury
Nephrotic syndrome is a result of ________ in the glomeruli in response to ___________.
loss of serum albumin causes a lowering of oncotic pressure; causing fluids to move into tissue
Why does edema occur in Nephrotic Syndrome?
hyperlipidemia; edema
The decrease in oncotic pressure leads to ________ & ________.
non-proliferative structural alterations that lead to the thickening of the basement; causing glomerular sclerosis
Explain the histology of Nephrotic Syndrome.
hematuria, proteinuria, oliguria, hypertension
What are the signs of Nephritic Syndrome? (4)
changes within the glomeruli that lead mesangial/endothelial proliferation & inflammatory cell infiltration
Explain the histology of Nephritic Syndrome.
diffuse proliferation
Rapidly Progressive glomerulonephritis (RPGN) is a consequence of advanced _______.
extensive crescent formation, rapid progressive renal dysfunction
What are the signs of RPGN? (2)
they are a part of the necrotizing histological response; resulting from thrombosis & rupture of glomerular capillaries
Why do crescents form in RPGN? (2)