Flashcards: Myeloid neoplasia

The myelodysplastic syndromes (also known as MDS or myelodysplasia) are hematological (i.e., blood-related) medical conditions that cause ineffective production (or "dysplasia") of all blood cells.

Polycythemia (or Polycythaemia, see spelling differences) vera (PV) (also known as erythremia, primary polycythemia, Vaquez disease, Osler-Vaquez disease and polycythemia rubra vera) is a neoplasm in which the bone marrow makes too many red blood cells.

The myeloproliferative neoplasms (MPNs), previously myeloproliferative diseases (MPDs), are a group of diseases of the bone marrow in which excess cells are produced.

Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).

Refractory cytopenia with multilineage dysplasia is a form of myelodysplastic syndrome.

The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.

The International Prognostic Scoring System (IPSS) is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS).

Refractory anemia with ring sideroblasts (RARS) is a type of myelodysplastic syndrome.

Chromosome 5q deletion syndrome (chromosome 5q monosomy, 5q- syndrome) is an acquired, hematological disorder characterized by loss of part of the long arm (q arm, band 5q33.1) of human chromosome 5 in bone marrow myelocyte cells.

Myelofibrosis, also known as osteomyelofibrosis, is a relatively rare bone marrow cancer.

Refractory anemia with excess of blasts (RAEB) is a type of myelodysplastic syndrome with a marrow blast percentage of 5% to 19%.

Essential thrombocytosis (ET; also known as essential thrombocythemia, essential thrombocythaemia, primary thrombocytosis) is a rare chronic blood disorder characterised by the overproduction of platelets by megakaryocytes in the bone marrow.