Flashcards: Muscle relaxants

Pancuronium (trademarked as Pavulon) is a muscle relaxant with various medical uses.

Atracurium besilate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Tizanidine (trade names Zanaflex (Acorda Therapeutics), Sirdalud (Novartis), Relentus (Beximco Pharma)) is a drug that is used as a muscle relaxant.

Amyl nitrite is a chemical compound with the formula C5H11ONO.

Tubocurarine (also known as d-tubocurarine or DTC) is a toxic alkaloid historically known for its use as an arrow poison.

Phenibut (fenibut, phenybut; brand names Noofen and Citrocard), contracted from β-phenyl-γ-aminobutyric acid (β-phenyl-GABA), is a central depressant and analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), or a GABA analogue.

Tolperisone, a piperidine derivative, is a centrally acting muscle relaxant.

Pipecuronium (Arduan) is a bisquaternary aminosteroid muscle relaxant which acts at the nicotinic acetylcholine receptor of the neuromuscular junction.

Chloroethane or monochloroethane, commonly known by its old name ethyl chloride, is a chemical compound with chemical formula C2H5Cl, once widely used in producing tetraethyllead, a gasoline additive.

Meprobamate — marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others — is a carbamate derivative used as an anxiolytic drug.

Botulinum toxin (BTX) is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species.

Suxamethonium chloride, also known as suxamethonium or succinylcholine, is a medication used to induce muscle relaxation and short-term paralysis, usually to help with tracheal intubation.

Curare /kʊˈrɑːri/ or /kjʊˈrɑːri/ is a common name for various plant extract alkaloid arrow poisons originating from Central and South America.

Cisatracurium (formerly recognized as 51W89, and marketed as Nimbex) is a bisbenzyltetrahydroisoquinolinium that has effect as a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Vecuronium bromide (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents.

Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells.

Rocuronium (Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation.

Febarbamate (INN; Solium, Tymium), also known as phenobamate, is an anxiolytic and tranquilizer of the barbiturate and carbamate families which is used in Europe by itself and as part of a combination drug formulation called tetrabamate.

Hexafluronium (or hexafluorenium) is a muscle relaxant.

Candocuronium iodide (INN, formerly chandonium, HS-310) is the prototypical azasteroidal neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs.

Difebarbamate (INN) is a tranquilizer of the barbiturate and carbamate families which is used in Europe as a component of a combination drug formulation referred to as tetrabamate (Atrium, Sevrium).

Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.

BW A444U was an experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, intended to be used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Chlorphenesin carbamate (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms.

Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug.

Carisoprodol, marketed under the brand name Soma among others, is a prescription drug marketed since 1959.

Quazepam (marketed under brand names Doral, Dormalin) is a benzodiazepine derivative drug developed by the Schering Corporation in the 1970s.

Norgesic is the brand name of a muscle relaxant.

Orphenadrine (sold under many brand names worldwide) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine.

Pridinol is a muscle relaxant that is used as an antiparkinsonian and anticholinergic drug.

Doxacurium chloride (formerly recognized as BW938U80 or BW A938U) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Chlormezanone (marketed under the brandname Trancopal or Fenaprim) is a drug used as an anxiolytic and a muscle relaxant.

Promoxolane (Dimethylane) is a centrally acting muscle relaxant and anxiolytic drug.

A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone.

Cyclobenzaprine, sold under the brand name Flexeril among others, is a muscle relaxer medication used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions.

Mephenesin is a centrally acting muscle relaxant.

Dihexyverine is an antimuscarinic pharmaceutical drug related to dicycloverine used as a spasmolytic.

Medrylamine is an antihistamine related to diphenhydramine.

Zoxazolamine (INN, USAN, BAN) (brand name Contrazole, Deflexol, Flexin, Miazol, Uri-Boi, Zoxamine, Zoxine) is a muscle relaxant that is no longer marketed.

Flavoxate is an anticholinergic with antimuscarinic effects.

Lorbamate (INN; Abbott-19,957) is a muscle relaxant and tranquilizer of the carbamate family which was never marketed.

Alcuronium is a neuromuscular blocking (NMB) agent, alternatively referred to as a skeletal muscle relaxant.

Gallamine triethiodide (Flaxedil) is a non-depolarising muscle relaxant.

Rapacuronium (Raplon) is a rapidly acting, non-depolarizing neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care.

Suxethonium (trade name: Brevidil-E) is a depolarising muscle relaxant which is presented as a dry powder in an ampoule.

Chlorzoxazone (INN) is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort.

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.

Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis.

Emylcamate (marketed as Striatran by Merck) is an anxiolytic and muscle relaxant.

Phenprobamate (Gamaquil, Isotonil) is a centrally acting skeletal muscle relaxant, with additional sedative and anticonvulsant effects.

Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku.

GYKI-52466 is a 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist, which is a non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively), orally-active anticonvulsant, and skeletal muscle relaxant.

Gantacurium chloride (formerly recognized as GW280430A and as AV430A) is a new experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Tetrabamate (Atrium, G Tril, Sevrium) is a combination drug formulation of febarbamate, difebarbamate, and phenobarbital which was marketed in France and Spain and was used to treat anxiety and alcohol withdrawal-associated muscle tremors, agitation, and depression.

Dihydrochandonium is an antinicotinic non-depolarizing muscle relaxant.

Inaperisone (INN) is a muscle relaxant.

Lanperisone (INN) is a muscle relaxant.

Silperisone (INN) is a muscle relaxant.