Flashcards: Mitotic inhibitors

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol.

Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers.

Vinblastine is a medication used to treat a number of types of cancer including: Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, and testicular cancer among others.

Vinflunine (INN, trade name Javlor) is a novel fluorinated Vinca alkaloid undergoing research for the treatment of bladder cancer.

Neoxaline is a bio-active Aspergillus japonicus isolate.

Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent.

Vindesine is an anti-mitotic vinca alkaloid used in chemotherapy.

Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is an epothilone B analog developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer.

Vincristine, also known as leurocristine and marketed under the brandname Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer.

Cabazitaxel (previously XRP-6258, trade name Jevtana) is a semi-synthetic derivative of a natural taxoid.

Docetaxel is a well-established anti-mitotic chemotherapy medication that works by interfering with cell division.

Taxoids are a class of derivatives from taxol, that is, paclitaxel.

Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat breast cancer, lung cancer and pancreatic cancer, among others.

Ortataxel is a drug used in chemotherapy.

Tesetaxel (DJ-927) is a drug being investigated for chemotherapy of various types of cancer, including breast cancer, gastric cancer, and other solid tumours.

Larotaxel (code names XRP9881, RPR109881) is a drug of the taxane type that has been used experimentally in chemotherapy.

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent.

Vinorelbine (NVB), sold under the trade name Navelbine, is a chemotherapy medication that is used to treat a number of types of cancer, including breast cancer and non-small cell lung cancer.