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Flashcards: MicroBio Study Guide: Antibiotics
Antibiotics are what ?
Pharmaceuticals that help stop infection caused by Bacteria.
How does Antibiotics Stop Bacteria?
It Kills them or stops them from reproducing
What does Antibiotic mean?
"Against Life"
What does Antibiotic Resistance means?
Unable to kill or Stop Bacteria or germs
What is Ampicillin?
Its an irreversible inhibitor of the enzyme Transpeptidase
What is Transpeptidase used for ?
Bacteria needs it to make their Cell Walls
Ampicillin affects "mostly" what ?
Gram + bacteria
Ampicillin affects "some" what?
Gram - Bacteria
Chloramphenicol does what?
Binds to 50S subunit of the 70S ribosome and impairs peptidyl Transferase Activity
Chloramphenicol inhibits protein synthesis in both __ and __
Prokaryotic and Eukaryotic Ribosomes
Chloramphenicol mm Resistance
12
Chloramphenicol mm Intermediate
13-17
Chloramphenicol mm Sensitive
18
Chloramphenicol Mode of action
Inhibits protein Synthesis
Erythromycin mm resistance
13
Erythromycin mm Intermediate
14-17
Erythromycin mm Sensitive
18
Erythromycin mode of Action
Inhibits protein Synthesis
Kanamycin mm Resistance
13
Kanamycin mm Intermediate
14-17
Kanamycin mm Sensitive
18
Kanamycin mode of action
Inhibits protein Synthesis
Neomycin mm Resistance
12
Neomycin mm intermediate
13-16
Neomycin mm Sensitive
17
Neomycin Mode of action
Inhibits protein synthesis
Novobiocin mm Resistant
17
Novobiocin mm Intermediate
18-21
Novobiocin mm Sensitive
22
Novobiocin Mode of action
Inhibits DNA Gyrase Gram+
Penicillin/Staphylococcus Resistant mm
20
Penicillin/Staphylococcus Intermediate mm
21-28
Penicillin/Staphylococcus Sensitive mm
29
Penicillin/other Resistant mm
11
Penicillin/other Intermediate mm
12-21
Penicillin/other Sensitive mm
22
Penicillin/Staphylococcus Mode of action
Inhibits Cell Wall Synthesis
Penicillin/other Mode of action
Inhibits Cell Wall Synthesis
Streptomycin Resistant mm
11
Streptomycin Intermediate mm
12-14
Streptomycin Sensitive mm
15
Streptomycin Mode of action
Inhibits Cell Wall Synthesis
Tetracycline Resistant mm
14
Tetracycline Intermediate mm
15-18
Tetracycline Sensitive mm
19
Tetracycline Mode of action
Inhibits protein synthesis
Vancomycin Resistant mm
9
Vancomycin Intermediate mm
10-11
Vancomycin Sensitive mm
12
Vancomycin Mode of action
Inhibits Cell Wall Synthesis