5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
3beta-Hydroxysteroid dehydrogenase
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) (EC 1.1.1.145) is an enzyme that catalyzes the biosynthesis of progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
CD1
CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.
Steroid 11-beta-hydroxylase
Steroid 11β-hydroxylase is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata.
Pramlintide
Pramlintide (Symlin) is an injectable amylin analogue drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca).
Neuroligin
Neuroligin (NLGN), a type I membrane protein, is a cell adhesion protein on the postsynaptic membrane that mediates the formation and maintenance of synapses between neurons.
Myoglobin
Myoglobin (symbol Mb or MB) is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals.
Claudin
Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium.
CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
Hepatocyte nuclear factor 4 alpha
(See also: MODY 1) Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is encoded by the HNF4A gene.
ADAM10
A Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by the ADAM10 gene.
Profilin
Profilin is an actin-binding protein involved in the dynamic turnover and restructuring of the actin cytoskeleton.
C11orf73
C11orf73 is a protein important in lung and multicellular organismal development that, in humans, is encoded by the C11orf73 gene (chromosome 11 open reading frame 73).
FAM200A
C7orf38 is a gene located on chromosome 7 in the human genome.
Insulin aspart
Insulin aspart is a fast-acting insulin analog marketed by Novo Nordisk as NovoLog/NovoRapid.
Methylmalonyl-CoA mutase
Methylmalonyl Coenzyme A mutase, also known as MCM is an enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA and it is involved in key metabolic pathways.
Regular insulin
Regular insulin includes regular human insulin also known as human insulin (regular) and is a short acting insulin.
Caspase-activated DNase
Caspase-Activated DNase (CAD) or DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene.
Nelivaptan
Nelivaptan (INN), codenamed SSR-149,415, is a selective and orally active non-peptide vasopressin receptor antagonist selective for the V1b subtype.
Insulin degludec
Insulin degludec (INN/USAN) is an ultralong-acting basal insulin analogue that was developed by Novo Nordisk under the brand name Tresiba.
Insulin lispro
Insulin lispro (marketed by Eli Lilly and Company as Humalog) is a fast acting insulin analog.
Myelin protein zero
Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene.
ANLN
Anillin is a conserved protein implicated in cytoskeletal dynamics during cellularization and cytokinesis.
Voltage sensitive phosphatase
Voltage sensitive phosphatases or voltage sensor-containing phosphatases, commonly abbreviated VSPs, are a protein family found in many species, including humans, mice, zebrafish, frogs, and sea squirt.
Glucagon rescue
Glucagon rescue is the emergency injection of glucagon in case of severe diabetic hypoglycemia.
MTORC1
mTORC1, also known as mammalian target of rapamycin complex 1 or mechanistic target of rapamycin complex 1, is a protein complex that functions as a nutrient/energy/redox sensor and controls protein synthesis.
Pappalysin-1
Pappalysin-1 (EC 3.4.24.79, insulin-like growth factor binding protein-4 protease, pregnancy-associated plasma protein-A) is an enzyme.
2700099C18Rik
NDC80 homolog, kinetochore complex component pseudogene is a protein that in humans is encoded by the 2700099C18Rik gene.
FRA3A
Fragile site, aphidicolin type, common, fra(3)(p24.2) is a protein that in humans is encoded by the FRA3A gene.
FTH1P5
Ferritin, heavy polypeptide 1 pseudogene 5 is a protein that in humans is encoded by the FTH1P5 gene.
PPP1R27
Protein phosphatase 1, regulatory subunit 27 is a protein in humans that is encoded by the PPP1R27 gene.
RERG
RAS-like, estrogen-regulated, growth inhibitor is a protein in humans that is encoded by the RERG gene.
DNAH7
Dynein, axonemal, heavy chain 7 is a protein in humans that is encoded by the DNAH7 gene.
MTORC2
mTOR Complex 2 (mTORC2) is a protein complex that regulates cellular metabolism as well as the cytoskeleton.
SLFN12
Schlafen family member 12 is a protein in humans that is encoded by the SLFN12 gene.
Alpha-2 adrenergic receptor
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.
2',3'-Cyclic-nucleotide 3'-phosphodiesterase
2',3'-Cyclic-nucleotide 3'-phosphodiesterase also known as CNPase is an enzyme that in humans is encoded by the CNP gene.
7-Dehydrocholesterol reductase
7-dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the DHCR7 gene.
Insulin glargine
Insulin glargine, marketed under the names Lantus among others, is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes.
NDUFB11
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (NADH-ubiquinone oxidoreductase ESSS subunit) is an enzyme that in humans is encoded by the NDUFB11 gene.
Sclerostin
Sclerostin is a protein that in humans is encoded by the SOST gene.
CAPN8
Calpain 8 is a protein in humans that is encoded by the CAPN8 gene.
OR6C75
Olfactory receptor, family 6, subfamily C, member 75 is a protein in humans that is encoded by the OR6C75 gene.
POTEB
POTE ankyrin domain family, member B is a protein in humans that is encoded by the POTEB gene.
PYGO1
Pygopus homolog 1 (Drosophila) is a protein in humans that is encoded by the PYGO1 gene.
STOX1
Storkhead box 1 is a protein in humans that is encoded by the STOX1 gene.
FAM3D
Family with sequence similarity 3, member D is a protein that in humans is encoded by the FAM3D gene.
IGLJ3
Immunoglobulin lambda joining 3 is a protein that in humans is encoded by the IGLJ3 gene.
MIR95
MicroRNA 95 is a protein that in humans is encoded by the MIR95 gene.
TESPA1
Thymocyte expressed, positive selection associated 1 is a protein that in humans is encoded by the TESPA1 gene.
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 is a protein that in humans is encoded by the WFIKKN2 gene.
LOC100533655
Aryl hydrocarbon receptor pseudogene is a protein that in humans is encoded by the LOC100533655 gene.
POLR3G
Polymerase (RNA) III (DNA directed) polypeptide G (32kD) is a protein that in humans is encoded by the POLR3G gene.
Dynein, axonemal, heavy chain 14
Dynein, axonemal, heavy chain 14 is a protein that in humans is encoded by the DNAH14 gene.
PRR35
Proline rich 35 is a protein that in humans is encoded by the PRR35 gene.
Perilipin
Perilipin, also known as lipid droplet-associated protein or PLIN, is a protein that, in humans, is encoded by the PLIN gene.
Mevalonate kinase
Mevalonate kinase is an enzyme that in humans is encoded by the MVK gene.
SETD6
SET domain containing 6 is a protein in humans that is encoded by the SETD6 gene.
SLX4IP
SLX4 interacting protein is a protein that in humans is encoded by the SLX4IP gene.
TONSL
Tonsoku-like, DNA repair protein is a protein that in humans is encoded by the TONSL gene.
ZDHHC14
Zinc finger, DHHC-type containing 14 is a protein that in humans is encoded by the ZDHHC14 gene.
FRA1J
Fragile site, 5-azacytidine type, common, fra(1)(q12) is a protein that in humans is encoded by the FRA1J gene.
NBEAL1
Neurobeachin-like 1 is a protein that in humans is encoded by the NBEAL1 gene.
LOC105377021
Function: The explicit function is unknown, however based on bioinformatic data presented herein, LOC105377021 is estimated to play a maintenance role in the nucleus of the cell.
PABPC4L
Poly(A) binding protein, cytoplasmic 4-like is a protein that in humans is encoded by the PABPC4L gene.
DFNY1
Deafness, Y-linked 1 is a protein that in humans is encoded by the DFNY1 gene.
ELL3
Elongation factor RNA polymerase II-like 3 is a protein that in humans is encoded by the ELL3 gene.
HOXA10-HOXA9
HOXA10-HOXA9 readthrough is a gene that is unlikely to produce a protein product.
LINC01137
Long intergenic non-protein coding RNA 1137 is a protein that in humans is encoded by the LINC01137 gene.
TTC28
Tetratricopeptide repeat domain 28 is a protein that in humans is encoded by the TTC28 gene.