Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, used to treat a variety of inflammatory and autoimmune conditions and some cancers.
Oxypurinol
Oxypurinol is an inhibitor of xanthine oxidase.
Oxazepam
Oxazepam is a short-to-intermediate-acting benzodiazepine.
Desloratadine
Desloratadine is a tricyclic H1-antihistamine that is used to treat allergies.
Gentisic acid
Gentisic acid is a dihydroxybenzoic acid.
Carboxycyclophosphamide
Carboxycyclophosphamide is an inactive metabolite of the cytotoxic antineoplastic drug cyclophosphamide.
Meta-Chlorophenylpiperazine
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class.
DrugBank
The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets.
Teriflunomide
Teriflunomide (trade name Aubagio, marketed by Sanofi) is the active metabolite of leflunomide.
Penicillamine
Penicillamine, sold under the trade names of Cuprimine, Cuprenyl and Depen, is a medication of the chelator class.
Paliperidone
Paliperidone (trade name Invega), also known as 9-hydroxyrisperidone, is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications.
Tizoxanide
Tizoxanide, also known as desacetyl-nitazoxanide, is a thiazolide and an antiparasitic agent that occurs as a metabolite of nitazoxanide in humans through hydrolysis.
Hydroxycarteolol
Hydroxycarteolol is a beta blocker and metabolite of carteolol.
Ampyrone
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties.
N-Desalkylflurazepam
N-Desalkylflurazepam (also known as Norflurazepam) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, quazepam, and ethyl loflazepate.
Hydroxybupropion
Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion.
Penicilloic acid
Penicilloic acid is any of several acids which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase).
Nordazepam
Nordazepam (INN; marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday; also known as nordiazepam, desoxydemoxepam, and desmethyldiazepam) is a 1,4-benzodiazepine derivative.
3-Methoxymorphinan
3-Methoxymorphinan is a levomethorphan metabolite that has been shown to produce local anesthetic effects.
Afimoxifene
Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT, 4-HT, OHTAM, others), is a selective estrogen receptor modulator and the active metabolite of tamoxifen.
N-Acetylprocainamide
N-Acetylprocainamide (NAPA or acecainide) is the N-acetylated metabolite of procainamide.
19-Norandrosterone
19-Norandrosterone is a nandrolone derivative and bolandione metabolite.
3-Hydroxyphenazepam
3-Hydroxyphenazepam is a benzodiazepine with hypnotic, sedative, anxiolytic, and anticonvulsant properties.
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) is a major metabolite of methadone.
Licarbazepine
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine.
Norpethidine
Norpethidine (normeperidine, pethidine intermediate B) is a 4-phenylpiperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine).
Seproxetine
Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI).
Cocaethylene
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine.
Tryptophol
Tryptophol is an aromatic alcohol that induces sleep in humans.
Dehydronorketamine
Dehydronorketamine (DHNK), or 5,6-dehydronorketamine, is a minor metabolite of ketamine which is formed by dehydrogenation of its metabolite norketamine.
Modafinil sulfone
Modafinil sulfone (code name CRL-41056) is an achiral, oxidized metabolite of modafinil, a wakefulness-promoting agent.
Phenylethylmalonamide
Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.
Modafinil acid
Modafinil acid (code name CRL-40467), also known as modafinilic acid or modafinil carboxylate, is the major metabolite of modafinil, and one of the two major metabolites of modafinil – the other being modafinil sulfone.
Desvenlafaxine
Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer).
NAPQI
NAPQI (N-acetyl-p-benzoquinone imine) is a toxic byproduct produced during the xenobiotic metabolism of the analgesic paracetamol (acetaminophen).
Naloxol
Naloxol is an opioid antagonist closely related to naloxone.
Didesmethylcitalopram
Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic).
AM404
AM404, also known as N-arachidonoylaminophenol, is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action.
Desmethylsertraline
Desmethylsertraline (DMS), also known as norsertraline, is an active metabolite of the antidepressant drug sertraline.
Desmethylcitalopram
Desmethylcitalopram is an active metabolite of the antidepressant drugs citalopram (racemic) and escitalopram (the S-enantiomer, which would be called desmethylescitalopram).
Desmethylclozapine
N-Desmethylclozapine (NDMC), or norclozapine, is a major active metabolite of the atypical antipsychotic drug clozapine.