TCA, BB, CCB
Which drugs should we avoid with a2-agonists? (3)
adjunctive due to AE's
How does A2-agonist prescribing work?
decreased efficacy
TCAs + A2 Agonist =
bradycardia
BB/CCB + A2 Agonist =
increased BP, agitation, headache, tremors
What can happen if someone abruptly stops taking Clonidine? (4)
long term tx; high doses
Clonidine withdrawal is worse with _______ & _______.
beta blocker
When discontinuing Clonidine, _______ should be discontinued first.
b
Withdrawal symptoms are worse in ________.
a) patch
b) oral
once a week
How often does someone take the Clonidine patch?
takes 2-3 days for patch to work; overlap 1-2 days
How does switching from Oral-->Patch work?
start oral >=8 hours after patch removal
How does switching from Patch--> Oral work?
not using epidural clonidine; causing hypotension/bradycardia
BBW for Clonidine?
<=0.1 mg every 3-7 days
How does Kapvay (Clonidine ER) tapering work?
b
Which has a greater incidence of edema?
a) clonidine
b) methyldopa
BID
How is Methyldopa dosed?
QD
BID
TID
QID
b
Which can cause hepatitis & hemolytic anemia?
a) clonidine
b) methyldopa
thiazides
What can we give to patients to avoid Methyldopa-induced tachyphlyaxis?
b
Which is the DOC for HTN in pregnancy?
a) clonidine
b) methyldopa