Flashcards: Growth factors

Fibroblast growth factors, or FGFs, are a family of growth factors, with members involved in angiogenesis, wound healing, embryonic development and various endocrine signaling pathways.

Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene.

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis.

Erythropoietin (/ɪˌrɪθroʊˈpɔɪᵻtən/ or /ɪˌrɪθroʊpoʊˈɛtɪn, -rə-, -ˈiː-, -tən/; from Greek: ἐρυθρός, erythros 'red' and ποιεῖν, poiein 'make'), also known as EPO, hematopoietin, or hemopoietin, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production.

Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene.

Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family.

Platelet-derived growth factor (PDGF) is one of the numerous growth factors, or proteins that regulate cell growth and division.

Angiopoietin is part of a family of vascular growth factors that play a role in embryonic and postnatal angiogenesis.

In platelets, the term "alpha granules" is used to describe granules containing several growth factors.

Epidermal growth factor (EGF) is a growth factor that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR.

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine.

Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin.

Epoetin beta (rINN) /ɛˈpoʊ.

Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.

Glia maturation factor is a neurotrophic factor implicated in nervous system development, angiogenesis and immune function.

Darbepoetin alfa (rINN) /dɑːrbəˈpɔɪtᵻn/ is a synthetic form of erythropoietin.

Epoetin alfa (rINN) /ɛˈpoʊ.

Filgrastim is a granulocyte colony-stimulating factor (G-CSF) analog used to stimulate the proliferation and differentiation of granulocytes; it is a pharmaceutical analog of naturally occurring G-CSF.

Palifermin (trade name Kepivance, marketed by Biovitrum) is a truncated human recombinant keratinocyte growth factor (KGF) produced in Escherichia coli.