Flashcards: Glucocorticoids

Prednimustine is a drug used in chemotherapy.

Fluticasone is a synthetic glucocorticoid.

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.

17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP) (INN, BAN), also known as 17α-hydroxypregn-4-ene-3,20-dione, is an endogenous progestogen steroid hormone related to progesterone.

Cortisol is a steroid hormone, in the glucocorticoid class of hormones.

11-Deoxycortisol, also known as cortodoxone (INN, USAN, BAN), as well as 17α-hydroxy-11-deoxycorticosterone, 17α,21-dihydroxyprogesterone, and cortexolone, is a glucocorticoid steroid hormone.

Prednicarbate is a relatively new topical corticosteroid drug.

Triamcinolone is a long-acting synthetic corticosteroid given orally, by injection, by inhalation, or as a topical ointment or cream.

Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, used to treat a variety of inflammatory and autoimmune conditions and some cancers.

Betamethasone is a steroid medication.

Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug.

Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching.

Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication.

Budesonide (BUD), sold under the brand name Pulmicort among others, is a steroid medication.

Dexamethasone is a type of steroid medication.

Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.

Cortisone (/ˈkɔːrtᵻsoʊn/ or /ˈkɔːrtᵻzoʊn/; 17-hydroxy-11-dehydrocorticosterone) is a 21-carbon steroid hormone.

Ciclesonide is a glucocorticoid used to treat asthma and allergic rhinitis.

Prednylidene is a glucocorticoid for systemic use.

3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone.

Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis.

Quingestrone (INN, USAN) (brand name Enol-Luteovis; former developmental code name W-3399), also known as progesterone 3-cyclopentyl enol ether (PCPE) or as 3-cyclopentyloxypregna-3,5-dien-20-one, is a semisynthetic, steroidal, pure progestin that was developed by Vister and introduced in Italy as an oral contraceptive (in combination with ethinyl estradiol or mestranol) in 1962.

Paramethasone is a fluorinated glucocorticoid with anti-inflammatory and immunosuppressant properties.

Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations.

Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis.

Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

(R)-Perdesonide is one of the two isomers of perdesonide, a glucocorticoid steroid.

Perdesonide is a glucocorticoid steroid.

Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a steroidal progestin of the 17α-hydroxyprogesterone group and a synthetic derivative of the progestational steroid hormone progesterone.

Flumetasone (INN; or flumethasone) is a corticosteroid for topical use.

Segesterone acetate (USAN) (brand name Nestorone; former developmental code names ST-1435, AC-6844, CS-0411), known more commonly simply as nestorone (or nestoron), and also known as elcometrine, is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries.

Fluticasone furoate is a synthetic corticosteroid derived from fluticasone, marketed by GlaxoSmithKline as Veramyst (US) and Avamys (Australia, Canada, EU, South Africa, South America, Mexico, Israel, and South Korea) for the treatment of allergic rhinitis administered by a nasal spray.

Gestodene (INN, USAN, BAN), also known as 15(16)-dehydrolevonorgestrel, as well as 17α-ethynyl-18-methylestra-4,15-dien-17β-ol-3-one, is a steroidal progestin of the 19-nortestosterone group related to levonorgestrel that is used in combination with ethinyl estradiol as a hormonal contraceptive.

Tetrahydrogestrinone (THG), often referred to as The Clear, is an anabolic steroid developed by Patrick Arnold.

Promegestone (INN) (brand name Surgestone), also known as 17α,21-dimethyl-Δ9-19-norprogesterone or 17α,21-dimethyl-19-norpregna-4,9-diene-3,20-dione, is a steroidal progestin of the 19-norprogesterone group which was introduced in 1983 and is marketed in France, Portugal, and Argentina.

AZD5423 is a nonsteroidal glucocorticoid and phase II drug by AstraZeneca disclosed at the spring 2013 American Chemical Society meeting in New Orleans to treat respiratory diseases and in particular chronic obstructive pulmonary disease.

Osaterone (INN), or as osaterone acetate (brand name Ypozane; former developmental code name TZP-4238), also known as 17α-acetoxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone acetate, is a steroidal antiandrogen and progestogen used in veterinary medicine in Europe in the treatment of benign prostatic hyperplasia (BPH) in dogs.

Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.

Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid often prescribed as treatment for allergic rhinitis.

5α-Dihydrocorticosterone ((5α,11β)-11,21-dihydroxypregnane-3,20-dione; abbreviated as 5α-DHC, 5α-DHB) is a naturally-occurring, endogenous glucocorticoid steroid hormone and neurosteroid.

Mapracorat (INN, code names BOL-303242-X, ZK-245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs).

Medrogestone (INN, USAN, BAN) (brand name Colprone), or metrogestone, also known as 6,17α-dimethyl-6-dehydroprogesterone or 6,17α-dimethyl-4,6-pregnadiene-3,20-dione, is a steroidal progestin related to progesterone that is used in hormone replacement therapy and in the treatment of gynecological disorders.

Medrysone (INN, USAN), also known as 6α-Methyl-11β-hydroxyprogesterone or 11β-hydroxy-6α-methylpregn-4-ene-3,20-dione, is a corticosteroid that has been used in optometry, and in ophthalmology for the treatment of eye inflammations.

Megestrol acetate (MGA) (INN, USAN, BAN, JAN) (brand names Megace, Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin of the 17α-hydroxyprogesterone group that is used in the treatment of breast and endometrial cancer and as an appetite stimulant.

Meprednisone is a glucocorticoid.

Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein.

Metribolone (INN) (developmental code names R-1881 (or RU-1881), NSC-92858), also known as methyltrienolone (or 17α-methyltrenbolone), as well as 17α-methyl-19-nor-Δ9,11-testosterone or 17α-methyl-19-norandrosta-4,9,11-triene-17β-ol-3-one, is a highly potent, orally active, non-aromatizable anabolic-androgenic steroid (AAS) of the 19-nortestosterone and 17α-alkylated groups which was never marketed for clinical use but has been used in scientific research as a photoaffinity label for the androgen receptor (AR) and in AR ligand binding assays.

Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug.

Cyproterone acetate (abbreviated as CPA), also sold under brand names such as Androcur among others, is a synthetic steroidal antiandrogen, progestin, and antigonadotropin.

Cyproterone (INN) (developmental code name SH-80881), also known as 1,2α-methylene-6-chloro-δ6-17α-hydroxyprogesterone is a steroidal, pure antiandrogen that was studied in the mid to late 1960s and early 1970s but was never marketed for medical use.

Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.

Chlormadinone acetate (abbreviated as CMA) (INN, USAN, BAN, JAN) (sold under brand names including Clordion, Gestafortin, Lormin, Non-Ovlon, Normenon, Verton, and many others), and also known as 17α-acetoxy-6-chloro-6-dehydroprogesterone, is a steroidal progestin with additional antiandrogen and antigonadotropic (and by extension antiestrogenic) effects.

Chloroprednisone is a topical glucocorticoid first reported in 1960.

Delmadinone acetate (INN, USAN, BAN) (brand names Delmate, Estrex, Tardak, Tardastren, Tardastrex, Vetadinon, Zenadrex), sometimes abbreviated as DMA, and also known as 1,6-bisdehydro-6-chloro-17α-acetoxyprogesterone, is a steroidal progestin with antigonadotropic (and hence, antiandrogenic and antiestrogenic) properties which is used to treat androgen-associated conditions in veterinary medicine.

Hydrocortamate (Magnacort, Ulcortis) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties.

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery.