Flashcards: Genes on human chromosome 1

The actions of vasopressin are mediated by stimulation of tissue-specific G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into V1, V2 and V3 subtypes.

Presenilins are a family of related multi-pass transmembrane proteins which constitute the catalytic subunits of the gamma-secretase intramembrane protease complex.

11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) is the name of a family of enzymes that catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids to the steroid receptors: 11β-hydroxysteroid + NADP+ ⇌ an 11-oxosteroid + NADPH + H+ Thus, the two substrates of this enzyme are 11beta-hydroxysteroid and NADP+, whereas its 3 products are 11-oxosteroid, NADPH, and H+.

BarH-like homeobox 2 is a protein in humans that is encoded by the BARHL2 gene.

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide is a protein that in humans is encoded by the FCER1G gene.

Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.

The jumping translocation breakpoint protein (JTB), also knwon as prostate androgen-regulated protein (PAR), is a protein that in humans is encoded by the JTB gene.

Chromosome 1 open reading frame 35 is a protein in humans that is encoded by the C1orf35 gene.

DEP domain containing 1 is a protein in humans that is encoded by the DEPDC1 gene.

Zinc finger and BTB domain containing 48 is a protein that in humans is encoded by the ZBTB48 gene.

Zyg-11 family member B, cell cycle regulator is a protein that in humans is encoded by the ZYG11B gene.