Flashcards: DNA repair

DNA mismatch repair is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.

Photolyases (EC 4.1.99.3) are DNA repair enzymes that repair damage caused by exposure to ultraviolet light.

Very short patch (VSP) repair is a DNA repair system that removes GT mismatches created by the deamination of 5-methylcytosine to thymine.

Free radical damage to DNA can occur as a result of exposure to UV radiation or to radiomimetic compounds.

Excision endonuclease, also known as excinuclease or UV-Specific Endonuclease, is a nuclease (enzyme) which excises a fragment of nucleotides during DNA repair.

In molecular biology, the XPG-I is a protein domain found on Xeroderma Pigmentosum Complementation Group G (XPG) protein.

Ku is a dimeric protein complex that binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair.

RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA.

DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.

BioSentinel is a planned low-cost CubeSat spacecraft on an astrobiology mission that will use yeast to detect, measure, and compare the impact of deep space radiation on DNA repair over long time beyond low-Earth orbit.

DNA Repair and Mutagenesis is a college-level textbook about DNA repair and mutagenesis written by Errol Friedberg, Graham Walker, Wolfram Siede, Richard D.

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes involving mainly DNA repair and programmed cell death.

8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species and can result in a mismatched pairing with adenine resulting in G to T and C to A substitutions in the genome.