sensitivity
Ability to detect disease among those known to have the disease
true positives/ true positives + false negatives
What is the formula for Sensitivity?
Specificity
ability to detect the absence of disease among those known to NOT have the disease
b
Expressed as % of patients without disease who test negative.
a) sensitivity
b) specificity
a
Expressed as % of patients with disease who test positive.
a) sensitivity
b) specificity
true negatives/ true negatives + false positives
Formula for Specificity?
true negatives/ true negatives + false negatives
Formula for Negative predicative value?
true positives/ true positives + false positives
Formula for positive predicative value?
positive/negative predicative value
-focuses on the practical usefulness of the test in clinical practice.
purple; pink
Gram-positive stains _______ while Gram-negative stains _______.
c
Which susceptibility testing (by hand) is considered the gold standard?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
minimum inhibitory concentration (MIC)
-lowest concentration to prevent visible growth
Minimum bactericidal concentration (MBC)
-lowest concentration required to kill
a, c
Which tests provide a specific MIC when completed?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
a,b
Which tests are fast/easy to complete?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
c
Which test is time constraining?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
a
Which test is expensive?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
b
Which test is not as accurate in determining what is susceptible/not susceptible?
a) epsilometer test
b) disk diffusion
c) broth microdilution
d) gram-stain configuration
a, g
What type of infections do we test urine samples in?
a) RT infections
b) viral testing
c) CSF infections
d) Intra-abdominal infections
e) skin infections
f) bone/joint infections
g) urine
a
What type of infections do we conduct PCR of the nares in?
a) RT infections
b) viral testing
c) CSF infections
d) Intra-abdominal infections
e) skin infections
f) bone/joint infections
g) urine
a, f
Which type of infections do we use X-rays?
a) RT infections
b) viral testing
c) CSF infections
d) Intra-abdominal infections
e) skin infections
f) bone/joint infections
g) urine
d
Which fungal species will test positive for Beta-D-Glucan?
a) aspergillus
b) cryptococcus
c) Histoplasma
d) candida
a
Which fungal species will test positive for the cell wall component Galactomannan?
a) aspergillus
b) cryptococcus
c) histoplasma
d) candida
cryptococcus, histoplasmosis, Blastomyces, coccidioidomycosis
Which fungal species do we utilize antigen detection tests on? (4)
histoplasmosis, Blastomyces, coccidioidomycosis
What are our Dimorphic fungi? (3)