Sjögren's syndrome (SjS, SS) is a long-term autoimmune disease in which the moisture-producing glands of the body are affected.
Systemic sclerosis, or systemic scleroderma, is an autoimmune disease of the connective tissue.
Juvenile idiopathic arthritis
Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA), is the most common form of arthritis in children and adolescents.
Dermatomyositis (DM) is a connective-tissue disease related to polymyositis (PM) that is characterized by inflammation of the muscles and the skin.
Morphea, also known as "localized scleroderma", or "circumscribed scleroderma", involves isolated patches of hardened skin with no internal organ involvement.
Rheumatoid arthritis (RA) is a long-lasting autoimmune disorder that primarily affects joints.
Achondroplasia is a common cause of dwarfism.
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.
Ehlers–Danlos syndrome (EDS) is a group of genetic connective tissue disorders.
Winchester syndrome is a rare congenital connective tissue disease described in 1969, of which the main characteristics are short stature, marked contractures of joints, opacities in the cornea, a coarse face, dissolution of the carpal and tarsal bones (in the hands and feet, respectively) and osteoporosis.
Silicosis (previously miner's phthisis, grinder's asthma, potter's rot and other occupation-related names) is a form of occupational lung disease caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs.
Treacher Collins syndrome
Treacher Collins syndrome (TCS) is an autosomal dominant congenital disorder characterized by craniofacial deformities, involving ears, eyes and cheekbones and goes along with normal intelligence.
Mixed connective tissue disease
In medicine, mixed connective tissue disease (also known as Sharp's syndrome), commonly abbreviated as MCTD, is an autoimmune disease in which the body's defense system attacks itself.
Systemic-onset juvenile idiopathic arthritis
Systemic onset juvenile idiopathic arthritis (also known as systemic juvenile idiopathic arthritis (sJIA)) is a type of juvenile idiopathic arthritis (JIA) with extra-articular manifestations like fever and rash apart from arthritis.
Nephrogenic systemic fibrosis
Nephrogenic systemic fibrosis (NSF) or nephrogenic fibrosing dermopathy (NFD) is a rare and serious syndrome that involves fibrosis of skin, joints, eyes, and internal organs.
Toxic oil syndrome
Toxic oil syndrome or simply toxic syndrome (Spanish: síndrome del aceite tóxico or síndrome tóxico) is a musculoskeletal disease most famous for a 1981 outbreak in Spain which killed over 600 people and was likely caused by contaminated colza oil.
Fibrous ankylosis is a fibrous connective tissue process which results in decreased range of motion.
Gerodermia osteodysplastica (GO), also called geroderma osteodysplasticum and Walt Disney dwarfism, is a rare autosomal recessive connective tissue disorder included in the spectrum of cutis laxa syndromes.
Interstitial granulomatous dermatitis
Interstitial granulomatous dermatitis with arthritis is a condition that most commonly presents with symmetrical round-to-oval erythematous or violaceous plaques on the flanks, axillae, inner thighs, and lower abdomen.
Methotrexate-induced papular eruption
Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities.
Palisaded neutrophilic and granulomatous dermatitis
Palisaded neutrophilic and granulomatous dermaititis is usually associated with a well-defined connective tissue disease, lupus erythematosus or rheumatoid arthritis most commonly, and often presents with eroded or ulcerated symmetrically distributed umbilicated papules or nodules on the elbows.
Lupus erythematosus is a name given to a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues.
Parry–Romberg syndrome (also known as progressive hemifacial atrophy) is a rare disease characterized by progressive shrinkage and degeneration of the tissues beneath the skin, usually on only one side of the face (hemifacial atrophy) but occasionally extending to other parts of the body.
Relapsing polychondritis is a multi-systemic condition characterized by inflammation and deterioration of cartilage.
Eosinophilia–myalgia syndrome (EMS) is an incurable and sometimes fatal flu-like neurological condition linked to the ingestion of the dietary supplement L-tryptophan.
Undifferentiated connective tissue disease
Undifferentiated connective tissue disease (UCTD) is a disease in which the body mistakenly attacks its own tissues.
Scleredema, also known as Buschke disease, scleredema of Buschke, and scleredema adultorum, is a rare, self-limiting skin condition defined by progressive thickening and hardening of the skin, usually on the areas of the upper back, neck, shoulders and face.
Schmid metaphyseal chondrodysplasia
Schmid metaphyseal chondrodysplasia is a type of chondrodysplasia associated with a deficiency of collagen, type X, alpha 1.