Flashcards: Aromatic amines

Sulfanilic acid (4-aminobenzenesulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions.

Sulfadiazine is a sulfonamide antibiotic.

Pomalidomide (INN, codenamed CC-4047, also known as 3-amino-thalidomide, trade name Pomalyst in the U.S. and Imnovid in EU and Russia) is a derivative of thalidomide marketed by Celgene.

o-Phenylenediamine is an organic compound with the formula C6H4(NH2)2.

Sulbutiamine (brand name: Arcalion) is a synthetic derivative of thiamine (vitamin B1).

Mitoxantrone (INN, BAN, USAN; also known as Mitozantrone in Australia; trade name Novantrone) is an anthracenedione antineoplastic agent.

Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound and a natural monoamine alkaloid, a trace amine, and also the name of a class of chemicals with many members that are well known for their psychoactive and stimulant effects.

Luminol (C8H7N3O2) is a chemical that exhibits chemiluminescence, with a blue glow, when mixed with an appropriate oxidizing agent.

Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

Malachite green is an organic compound that is used as a dyestuff and controversially as an antimicrobial in aquaculture.

Benzidine (trivial name), also called 1,1'-biphenyl-4,4'-diamine (systematic name), is an organic compound with the formula (C6H4NH2)2.

Diphenylamine is an organic compound with the formula (C6H5)2NH.

p-Phenylenediamine (PPD) is an organic compound with the formula C6H4(NH2)2.

Dansyl amide is a reactive fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group.

Mepacrine (INN), also called quinacrine (USAN) or by the trade name Atabrine, is a drug with several medical applications.

Michler’s ketone is an organic compound with the formula of [(CH3)2NC6H4]2CO.

m-Phenylenediamine, also called 1,3-diaminobenzene, is an organic compound with the formula C6H4(NH2)2.

3,3'-Diaminobenzidine (DAB) is an organic compound that is both chemically and thermodynamically stable.

There are three isomers of toluidine, which are organic compounds.

Lapatinib (INN), used in the form of lapatinib ditosylate (USAN) (trade names Tykerb and Tyverb) is an orally active drug for breast cancer and other solid tumours.

Methyl anthranilate, also known as MA, methyl 2-aminobenzoate, or carbomethoxyaniline, is an ester of anthranilic acid.

Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections.

Carfentanil or carfentanyl (also known as 4-carbomethoxyfentanyl) is an analog of the synthetic opioid analgesic fentanyl.

Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.

Iclaprim (INN), codenamed AR-100 and RO-48-2622, is a diaminopyrimidine dihydrofolate reductase (DHFR)-inhibiting extended-spectrum antibiotic active against gram positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria.

Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.

3-Aminoacridine is an aminoacridine.

4,5-Diaminopyrimidine is a diaminopyrimidine.

4-Aminoacridine is an aminoacridine.

Afatinib (INN; trade name Gilotrif in the US and Giotrif in Europe, previously Tomtovok and Tovok) is a drug approved in United States, Europe, Taiwan, Mexico, Chile and Japan as well as other countries for the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim.

Ammeline (4,6-diamino-2-hydroxy-1,3,5-triazine) is a triazine derivative.

PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases.

Pazopanib (trade name Votrient) is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis.

5-Nitro-2-propoxyaniline, also known as P-4000 and Ultrasüss, is one of the strongest sweet-tasting substances known, about 4,000 times the intensity of sucrose (hence its alternate name, P-4000).

Crisnatol (BW-A770U) is an experimental anticancer agent.

Euflavine is an antiseptic and disinfectant.

Fenyramidol (INN) or phenyramidol (BAN, USAN), trade name Cabral, is a pharmaceutical drug which acts as a muscle relaxant.

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABAA receptor.

GelGreen is an intercalating nucleic acid stain used in molecular biology for agarose gel electrophoresis.

Oil Blue 35 is a blue anthraquinone dye used for colouring alcoholic and hydrocarbon based solvents, including oils, fats, and waxes.

Oil Blue A is a blue anthraquinone dye used for coluring cetain plastics such as polystyrene and acrylic resins, as well as other materials such as petroleum and inks.

2,4-Diaminopyrimidine is a diaminopyrimidine.

1,4-Diamino-2,3-dihydroanthraquinone is an anthraquinone dye used with Disperse Red 9 in colored smoke to introduce a violet color.

PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is one of the most abundant heterocyclic amines (HCAs) in cooked meat.

2-Aminoacridine is an aminoacridine.

Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication.

Alimemazine (INN), also known as trimeprazine (USAN and former BAN); brand names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine).

3,4-Diaminopyridine (or 3,4-DAP) is an organic compound with the formula C5H3N(NH2)2.

Anthramine (1-aminoanthracene) (an organic compound with the chemical formula C14H11N.) is a fluorescent general anesthetic.

Sulfamethoxazole (SMZ or SMX), is an antibiotic.

Levomepromazine (INN, BAN, USAN), also known as methotrimeprazine, is a phenothiazine neuroleptic drug.

Janus Green B is a basic dye and vital stain used in histology.

Dabigatran (Pradaxa, Prazaxa) is an anticoagulant medication that can be taken by mouth.

Melarsoprol is a medication used in the treatment of African trypanosomiasis (sleeping sickness).

Torasemide (rINN) or torsemide (USAN) is a pyridine-sulfonyl urea type loop diuretic mainly used in the management of edema associated with congestive heart failure.

Quinizarine Green SS, also called Solvent Green 3, C.

Ethylhexyl triazone (INCI) is an organic compound used in sunscreens to absorb UVB radiation.

Mabuterol is a selective β2 adrenoreceptor agonist.

Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

Neratinib (HKI-272) is a tyrosine kinase inhibitor under investigation for the treatment of breast cancer and other solid tumours.

GelRed is an intercalating nucleic acid stain used in molecular biology for agarose gel electrophoresis.

Phenazopyridine is a chemical which, when excreted into the urine, has a local analgesic effect.

Pyrimethamine (trade name Daraprim) is a medication used for protozoal infections.

Methyl blue is a chemical compound with the molecular formula C37H27N3Na2O9S3.

Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor.

Picloram is a systemic herbicide used for general woody plant control.

Ethacridine lactate (ethacridine monolactate monohydrate, acrinol, trade name Rivanol) is an aromatic organic compound based on acridine.

Rhodamine B /ˈroʊdəmiːn/ is a chemical compound and a dye.

9-Aminoacridine is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.

Disperse Red 11, also called C.

Disperse Red 9, also called C.

Trimetrexate is a quinazoline derivative.

AR-231,453 is an agonist for the suggested novel cannabinoid receptor GPR119.

Amido black 10B is an amino acid staining diazo dye used in biochemical research to stain for total protein on transferred membrane blots, such as the western blot.

Iscotrizinol (USAN, INCI diethylhexyl butamido triazone) is an organic compound used in sunscreens to absorb UVA and UVB radiation.

JTC-801 is an opioid analgesic drug used in scientific research.

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G.