Antidepressants Test and Flashcards

analglesic, prodrug, CYP2D6

Codeine:

Pharmacological class:

Prodrug or active:

Enzyme Substrate:

SSRI, active, CYP2D6, depression

Paroxetine/ Fluvoxamine:

Pharmacological class:

Prodrug or active:

Enzyme substrate:

Indication:

SNRI, active, CYP2D6, ADHD

Atomoxetine:

Pharmacological class:

Prodrug or active:

Enzyme Substrate:

Indication:

SSRI, active, CYP2C19, depression

Escitalopram, Citalopram, Sertraline

Pharmacological class:

Prodrug or active:

Enzyme substrate:

Indication:

TCA/ Mixed SNRI, active, CYP2C19 & CYP2D6; depression, OCD, chronic pain, migraine prophylaxis

Amitriptyline

Pharmacological class:

Prodrug or active:

Enzyme substrate:

Indication:

atypical antipsychotic, active, CYP1A2, schizophrenia

Clozapine

Pharmacological class:

Prodrug or active:

Enzyme substrate:

Indication:

anti-depressant, prodrug, CYP2B6, depression & smoking cessation

Bupropion

Pharmacological class:

Prodrug or active:

Enzyme substrate:

Indication:

Flashcards: Antidepressants