Flashcards: Anticoagulants

Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison.

Warfarin, also known by the brand names Coumadin among others, is an anticoagulant normally used to prevent the formation of blood clots in the blood vessels and their migration elsewhere in the body.

Heparin is an injectable blood thinner (anticoagulant).

Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (such as Hirudo medicinalis) that has a blood anticoagulant property.

Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired).

Rivaroxaban (BAY 59-7939) is an oral anticoagulant invented and manufactured by Bayer; in a number of countries it is marketed as Xarelto.

Fondaparinux (trade name Arixtra) is an anticoagulant medication chemically related to low molecular weight heparins.

Bromadiolone is a potent anticoagulant rodenticide.

Anagrelide (Agrylin/Xagrid, Shire and Thromboreductin, AOP Orphan Pharmaceuticals AG) is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets.

Betrixaban (INN, codenamed PRT-054,021) is an anticoagulant drug which acts as a direct factor Xa inhibitor.

Darexaban (YM150) is a direct inhibitor of factor Xa created by Astellas Pharma.

Pulvinone, an organic compound belonging to the esters, lactones, alcohols and butenolides classes, is a yellow crystalline solid.

Anisindione (brand name Miradon) is a synthetic anticoagulant and an indanedione derivative.

Defibrotide (Defitelio, Gentium) is a deoxyribonucleic acid derivative (single-stranded) derived from cow lung or porcine mucosa.

Hypercoagulability in pregnancy is the propensity of pregnant women to develop thrombosis (blood clots).

Nafamostat (INN), a synthetic serine protease inhibitor, is an anticoagulant.

Apixaban, sold under the tradename Eliquis, is an anticoagulant for the treatment of venous thromboembolic events.

Atromentin is a natural chemical compound found in Agaricomycetes fungi in the orders Agaricales and Thelephorales.

Coumachlor is a 1st genereation anticoagulant rodenticide which blocks formation of prothrombin and inhibits blood coagulation causing death by internal haemorrhage.

Otamixaban (INN) is an experimental injectable anticoagulant direct factor Xa inhibitor that was investigated for the treatment for acute coronary syndrome.

Edoxaban (DU-176b, trade names Savaysa, Lixiana) is an oral anticoagulant drug which acts as a direct factor Xa inhibitor.