Flashcards: Antiarrhythmic agents

Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is class Ia antiarrhythmic agent.

Chronotropic effects (from chrono-, meaning time, and tropos, "a turn") are those that change the heart rate.

Magnesium citrate is a magnesium preparation in salt form with citric acid in a 1:1 ratio (1 magnesium atom per citrate molecule).

Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.

Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area and to treat ventricular tachycardia.

Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of irregular heartbeats.

Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart.

Sotalol is a drug used in individuals with rhythm disturbances of the heart (cardiac arrhythmias).

Procainamide is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias.

Diltiazem (INN) (/dɪlˈtaɪəzɛm/) is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.

Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects.

Propafenone (/proʊˈpæfᵻnoʊn/ proh-PAF-i-nohn; brand name Rythmol SR or Rytmonorm) is a class 1C anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.

BRL-32872 is an experimental drug candidate that provides a novel approach to the treatment of cardiac arrhythmia.

Landiolol (INN) is a drug which acts as a highly cardioselective, ultra short-acting beta blocker.

Tazolol is a beta blocker with some utility in the treatment of heart disease.

Moracizine (INN) or moricizine (USAN) (trade name Ethmozine) is an antiarrhythmic of class IC.

Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.

Trimecaine (systematic name (2,4,6-trimethylphenylcarbamoylmethyl)diethylammonium chloride, chemical formula C15H25ClN2O) is an organic compound used as a local anesthetic and cardial antiarrhythmic.

Alinidine (ST567) is a negative chronotrope that was developed in the 1970s and 1980s.

N-Acetylprocainamide (NAPA or acecainide) is the N-acetylated metabolite of procainamide.

Asocainol is a class 1a anti-arrhythmic compound.

Actisomide is an antiarrhythmic drug that is made from Disopyramide.

Azimilide is a class ΙΙΙ antiarrhythmic drug (used to control abnormal heart rhythms).

Sematilide is an antiarrhythmic agent.

Indecainide (INN, trade name Decabid) is a class Ic antiarrhythmic agent.

Aprindine is a Class 1b antiarrhythmic agent.

Dronedarone (development codename SR33589 and marketed as Multaq) is a drug by Sanofi-Aventis, mainly for the indication of cardiac arrhythmias.

Verapamil (sold under ) is a calcium channel blocker used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and most recently, cluster headaches.

Phenytoin, sold under the brand name Dilantin among others, is an anti-seizure medication.

Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker.

Bretylium (also bretylium tosylate) is an antiarrhythmic agent.

Metildigoxin (INN, or medigoxin BAN, or methyldigoxin) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).

Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine.

Vomilenine is an intermediate chemical in the biosynthesis of ajmaline.

Bufagin is a toxic steroid C24H34O5 obtained from toad's milk, the poisonous secretion of a skin gland on the back of the neck of a large toad (Rhinella marina, synonym Bufo marinus, the Cane Toad).

Pilsicainide (INN) is an antiarrhythmic agent.

Pirolazamide (SC-26,438) is an antiarrhythmic agent that was never marked.

Nifekalant (INN) is a class III antiarrhythmic agent approved in Japan for the treatment of arrhythmias and ventricular tachycardia.

Rotigaptide (ZP-123) is a drug currently under clinical investigation for the treatment of cardiac arrhythmias – specifically atrial fibrillation.

Bunaftine (or bunaphtine) is an antiarrhythmic agent.

Mexiletine (INN) (sold under the trade name Mexitil) is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines.

Flecainide acetate (/flɛˈkeɪnaɪd/ US dict: fle·kā′·nīd) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity.

Celivarone is an experimental drug being tested for use in pharmacological antiarrhythmic therapy.

Clofilium is an antiarrhythmic agent.

Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent.

Vernakalant (INN; codenamed RSD1235, proposed tradenames Kynapid and Brinavess) is an investigational drug under regulatory review for the acute conversion of atrial fibrillation.

Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac [7] and Wolff-Parkinson-White syndrome.

Budiodarone (ATI-2042) is an antiarrhythmic agent and chemical analog of amiodarone that is currently being studied in clinical trials.

Cariporide is a selective Na+/H+ exchange inhibitor.

Diacetolol is the primary metabolite of acebutolol.