beta-lactam
MOA?
bulky r group blocks active site of b-lactamase enzymes
What is unique about anti-staph penicillins' structure?
Gm + with activity against staph (NOT MRSA)
spectrum?
mild-severe staph infections (severity depends on ROA)
uses?
active against penicillin-ase (beta-lactamase)
Resistance?
e
Which has no activity against MRSA?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
e) all of the above
a
Which is not used in the U.S. ?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
b,c
Which antibiotic(s) are available IV & IM?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
d
Which antibiotic(s) is available orally as a capsule?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
b,c
Which antibiotic(s) are used for severe staph infections?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
b
Which antibiotic(s) have SE's that cause neutropenia?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
d
Which antibiotic(s) are used to treat mild/moderate staph & impetigo?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin
d
Which antibiotic(s) cause abdominal pain & GI bleeding?
a) methicillin
b)Nafcillin
c) Oxacillin
d) Dicloxacillin