Flashcards: Anti-acne preparations

Tetracycline is an antibiotic used to treat a number of bacterial infections.

Glycolic acid (hydroacetic acid or hydroxyacetic acid); chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).

Benzoyl peroxide (BPO) is an organic compound in the peroxide family.

Azelaic acid is an organic compound with the formula (CH2)7(CO2H)2.

Minocycline (INN) is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group.

Sulfacetamide is a sulfonamide antibiotic.

Isotretinoin (INN), also known as 13-cis retinoic acid, is an oral pharmaceutical drug primarily used to treat severe nodular acne.

Clindamycin is an antibiotic useful for the treatment of a number of bacterial infections.

Spironolactone, marketed under the brand name Aldactone among others, is a medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.

Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa.

Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).

Motretinide is an anti-acne preparation and aromatic analog of retinoic acid.

The drug combination sulfacetamide/sulfur is a topical acne medication manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar.

Adapalene/benzoyl peroxide is a prescription drug combination for the treatment of severe acne vulgaris; marketed by Galderma under the trade name Epiduo.

Topterone (INN, USAN) (developmental code name WIN-17665), also known as 17α-propyltestosterone or 17α-propylandrost-4-en-17β-ol-3-one, is a steroidal antiandrogen that was first reported in 1978 and was developed for topical administration but, due to poor effectiveness, was never marketed.

Rosterolone (INN) (developmental code name SH-434), also known as 17α-propylmesterolone or 17β-hydroxy-1α-methyl-17α-propyl-5α-androstan-3-one, is a steroidal antiandrogen that was first reported in 1984 and was developed for topical administration but was never marketed.

Metogest (INN, USAN) (developmental code name SC-14207), also known as 16,16-dimethyl-19-nortestosterone, is a steroidal antiandrogen that was patented in 1975 and investigated as a treatment for acne but was never marketed.

Inocoterone (INN), or as inocoterone acetate (USAN) (developmental code names RU-882, RU-38882), also known as 17β-hydroxy-2,5-seco-A-dinorestr-9-en-5-one [acetate], is a non-steroidal antiandrogen that was developed in 1985 for topical administration but was never marketed.

Delanterone (INN) (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed.

Cioteronel (INN, USAN) (developmental code name CPC-10997; former tentative brand names Cyoctol, Ethocyn, X-Andron) is a non-steroidal antiandrogen that was never marketed.

Epristeride (SKF-105,657, ONO-9302) is a selective, transition state, non-competitive inhibitor of the type II isoform of the enzyme 5α-reductase, similarly to finasteride and turosteride.

Erythromycin/tretinoin (trade name 'Isotrexin') is a topical gel with two active ingredients: erythromycin 2% w/w and tretinoin 0.

Bicalutamide (brand name Casodex) is a synthetic non-steroidal antiandrogen (NSAA) that is used primarily in the treatment of prostate cancer.

Epiestriol (INN) (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (BAN), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak endogenous estrogen, and the 16β-epimer of estriol (which is 16α-hydroxy-17β-estradiol).

Flutamide (brand name Eulexin) is a synthetic, non-steroidal antiandrogen (NSAA) used primarily to treat prostate cancer.

Mesulfen is an anti-acne preparation as well as a scabicide.

Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions.

Tazarotene (marketed as Tazorac, Avage, Zorac, and Fabior) is a third-generation prescription topical retinoid sold as a cream, gel, or foam.

The drug combination benzoyl peroxide/clindamycin is a topical gel used for the treatment of acne.

Lymecycline is a tetracycline broad-spectrum antibiotic marketed by the pharmaceutical company Galderma.

Tretinoin is the pharmaceutical form of retinoic acid.

Cyproterone acetate (abbreviated as CPA), also sold under brand names such as Androcur among others, is a synthetic steroidal antiandrogen, progestin, and antigonadotropin.

The drug combination clindamycin/tretinoin (trade name Ziana and Veltin) is a topical acne treatment.