Flashcards: Anthelmintics

Ascaridole is a natural organic compound classified as a bicyclic monoterpene that has an unusual bridging peroxide functional group.

Mepacrine (INN), also called quinacrine (USAN) or by the trade name Atabrine, is a drug with several medical applications.

Pyrantel is an antinematodal thiophene.

Ivermectin is a medication that is effective against many types of parasites.

Levamisole, marketed under the trade name Ergamisol, is a medication used to treat parasitic worm infections.

Mebendazole (MBZ) is a medication used to treat a number of parasitic worm infestations.

Praziquantel, marketed as Biltricide, is an anthelmintic used for the treatment of tapeworms and flukes.

Albendazole, marketed as Albenza among others, is medication used for the treatment of a variety of parasitic worm infestations.

Hexylresorcinol is an organic compound with local anaesthetic, antiseptic and anthelmintic properties.

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host.

Suramin is an antiparasitic drug developed by Oskar Dressel and Richard Kothe of Bayer, Germany in 1916, and is still sold by Bayer under the brand name Germanin.

Bitoscanate is an organic chemical compound used in the treatment of hookworms.

Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.

Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively new class of anthelmintic (research into these compounds began in the early 1990s), which are suspected to achieve their anti-parasitic effect by a novel mechanism of action due to their ability to kill nematodes resistant to other anthelmintics.

Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.

Oxyclozanide is a salicylanilide anthelmintic.

Nitroscanate (trade name Lopatol) is an anthelmintic drug used in veterinary medicine to treat Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Uncinaria stenocephala, Taenia, and Dipylidium caninum (roundworms, hookworms and tapeworms).

Ciclobendazole is an anthelmintic.

Desaspidin is an anthelmintic.

Fenbendazole (Hoechst brand names Panacur and Safe-Guard, Intervet Panacur and Panacur Rabbit) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles and strongyloides and can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits and seals.

Flubendazole is an anthelmintic.

Milbemycin oxime (trade name Interceptor, marketed by Novartis) is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic.

Moxidectin (Milbemycin B) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.

Niclosamide (trade name Niclocide) is a teniacide in the anthelmintic family especially effective against cestodes that infect humans and many other animals.

Pyrvinium (Viprynium) is an anthelmintic effective for pinworms.

Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai.

Dithiazanine iodide is a chemical compound.

Befuraline (DIV-154) is a psychoactive drug and member of the piperazine chemical class which was developed in Germany in the 1970s.

Triclabendazole (commercial names: veterinary, liquid: Fasinex; human, tablets: Egaten, both manufactured by Novartis) is a member of the benzimidazole family of anthelmintics.

Rafoxanide is a salicylanilide used as an anthelmintic.

Oxfendazole is a broad spectrum benzimidazole anthelmintic.

Diatrizoic acid (or its anionic form, diatrizoate), also known as amidotrizoic acid, or 3,5-diacetamido-2,4,6-triiodobenzoic acid, is a radiocontrast agent containing iodine.

Flavaspidic acid BB is a phloroglucinol derivative found in the fern Dryopteris abbreviata.

Amoscanate (INN), also known as nithiocyamine, is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection.