Aminorex (Menocil, Apiquel, aminoxaphen, aminoxafen, McN-742) is a weight loss (anorectic) stimulant drug.
Amphetamine
Amphetamine (contracted from alpha‑methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
Phenylpropanolamine
Phenylpropanolamine (BAN and INN; PPA, β-hydroxyamphetamine), also known as the stereoisomers norephedrine and norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which is used as a stimulant, decongestant, and anorectic agent.
Fenfluramine
Fenfluramine (former brand names Pondimin, Ponderax and Adifax), also known as 3-trifluoromethyl-N-ethylamphetamine, is an anorectic that is no longer marketed.
Bupropion
Bupropion is a medication primarily used as an antidepressant and smoking cessation aid.
Exenatide
Exenatide (/ɛɡzˈɛnətaɪd/, INN, marketed as Byetta, Bydureon) is a glucagon-like peptide-1 agonist (GLP-1 agonist) medication, belonging to the group of incretin mimetics, approved in April 2005 for the treatment of diabetes mellitus type 2.
Sibutramine
Sibutramine (usually in the form of the hydrochloride monohydrate salt) is an oral anorexiant.
Dextroamphetamine
Dextroamphetamine (American English) or dexamfetamine (Commonwealth English) is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Phentermine
Phentermine (α,α-Dimethylphenethylamine), a contraction of "phenyl-tertiary-butylamine", is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine.
Phendimetrazine
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
Amfepramone
Amfepramone (INN) is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant.
Phenmetrazine
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.
Propylhexedrine
Propylhexedrine (Benzedrex, Obesin) is a stimulant drug that is used medicinally as a nasal decongestant (for relief of congestion due to colds, allergies and allergic rhinitis) and recreationally for its psychostimulant effects.
Etolorex
Etolorex is an anorectant of the amphetamine class.
Setazindol
Setazindol is an anorectic.
Fenbutrazate
Fenbutrazate (INN), also known as phenbutrazate (BAN), is a psychostimulant used as an appetite suppressant under the trade names Cafilon, Filon, and Sabacid in Europe, Japan, and Hong Kong.
4-Methylamphetamine
4-Methylamphetamine (4-MA; PAL-313; Aptrol; p-TAP) is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes.
GW-803430
GW-803430 (GW-3430) is a drug used in scientific research and is a selective non-peptide antagonist at the melanin concentrating hormone receptor MCH1.
SNAP-94847
SNAP-94847 is a drug used in scientific research, which is a selective, non-peptide antagonist at the melanin concentrating hormone receptor MCH1.
Benfluorex
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine patented and manufactured by a French pharmaceutical company Servier.
Methastyridone
Methastyridone is a centrally acting stimulant, whose mode of action differs from that of classical agents such as d-amphetamine.
Taranabant
Taranabant (codenamed MK-0364) is a cannabinoid receptor type 1 inverse agonist that was investigated as a potential treatment for obesity due to its anorectic effects.
Furfenorex
Furfenorex (Frugalan), also known as furfurylmethylamphetamine, is a stimulant drug which was developed in the 1960s and used as an appetite suppressant.
Tiflorex
Tiflorex, formerly known as flutiorex, is a stimulant amphetamine.
Clobenzorex
Clobenzorex (Asenlix, Dinintel, Finedal, Rexigen) is a stimulant drug of the phenethylamine and amphetamine chemical classes used as an appetite suppressant.
Drinabant
Drinabant (INN; AVE-1625) is a drug that acts as a selective CB1 receptor antagonist, which was under investigation varyingly by Sanofi-Aventis as a treatment for obesity, schizophrenia, Alzheimer's disease, Parkinson's disease, and nicotine dependence.
Clortermine
Clortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class.
2-Phenyl-3-aminobutane
2-Phenyl-3-aminobutane (also known as β-methylamphetamine) is a stimulant of the phenethylamine class that is closely related to its α-methyl analog Pentorex.
Pentorex
Pentorex (Modatrop), also known as phenpentermine or α,β-dimethylamphetamine, is a stimulant drug related to phentermine which is used as an anorectic to assist with weight loss.
Benzphetamine
Benzphetamine (brand name Didrex) is a substituted amphetamine used short-term along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program for weight loss.
Norfenfluramine
Norfenfluramine, or 3-trifluoromethylamphetamine, is a never-marketed drug of the amphetamine family which behaves as a serotonin and norepinephrine releasing agent and potent 5-HT2A, 5-HT2B, and 5-HT2C agonist.
Xylopropamine
Xylopropamine (Perhedrin, Esanin), also known as 3,4-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine classes which was developed and marketed as an appetite suppressant in the 1950s.
Acridorex
Acridorex (INN; BS 7573a) is an amphetamine which was investigated as an anorectic but does not appear to have ever been marketed.
Flucetorex
Flucetorex (INN) is an amphetamine which was investigated as an anorectic but does not appear to have ever been marketed.
Fenisorex
Fenisorex (INN, USAN, BAN) is an amphetamine-like anorectic drug which does not appear to have ever been marketed.
Norpropylhexedrine
Norpropylhexedrine (cyclohexylaminopropane) is a stimulant of the cycloalkylamine class and is the cycloalkane analog of amphetamine.
Oxifentorex
Oxifentorex (INN) is an amphetamine described as an anorectic which does not appear to have ever been marketed.
Picilorex
Picilorex (INN; brand name Roxenan) is an anorectic which is no longer marketed.
Morforex
Morforex (INN; Bo 637), also referable to as N-morpholinoethylamphetamine, is an anorectic which was never marketed.
Flumexadol
Flumexadol (INN) (developmental code name CERM-1841 or 1841-CERM) is a drug described and researched as a non-opioid analgesic which was never marketed.
WAY-161503
WAY-161503 is a full agonist of 5-HT2C receptors (Ki = 3.3 nM for displacement of DOI), ~6-fold less potent at 5-HT2A receptors (Ki = 18 nM) and 20-fold less potent at 5-HT2B receptors (Ki = 60 nM).
WAY-629
WAY-629 is a 5-HT2C agonist that reduces feeding behavior when administered to rats.
Rosonabant
Rosonabant (INN; E-6776) is a drug acting as a CB1 receptor antagonist/inverse agonist that was under investigation by Esteve as an appetite suppressant for the treatment of obesity.
Rimonabant
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) is an anorectic antiobesity drug that has been withdrawn from the market due to potentially serious side effects.
Fenfluramine/phentermine
The drug combination fenfluramine/phentermine, usually called fen-phen, was an anti-obesity treatment that utilized two anorectics.
P57 (glycoside)
P57 is an oxypregnane steroidal glycoside isolated from the African cactiform Hoodia gordonii.
Levophacetoperane
Levophacetoperane (Lidépran, Phacétoperane) is a psychostimulant developed by Rhône-Poulenc in the 1950s.
Amfepentorex
Amfepentorex is a stimulant drug derived from methamphetamine which is used as an appetite suppressant for the treatment of obesity.
Setmelanotide
Setmelanotide (INN, USAN) (code name RM-493, formerly BIM-22493, IRC-022493) is a peptide drug and investigational anti-obesity medication which acts as a selective agonist of the MC4 receptor.
Bupropion/zonisamide
Bupropion/zonisamide (planned trade name Empatic) is an experimental drug combination for the treatment of obesity.
Bupropion/naltrexone
Bupropion/naltrexone is a combination drug treatment for obesity.
Phentermine/topiramate
Phentermine and topiramate, sold under the trade name Qsymia, is a combination medication used for weight loss.
Chlorphentermine
Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a serotonergic appetite suppressant of the amphetamine family.
Ciclazindol
Ciclazindol (WY-23,409) is an antidepressant and anorectic drug of the tetracyclic chemical class that was developed in the mid to late 1970s, but was never marketed.
Amfecloral
Amfecloral (INN), also known as amphecloral (USAN), is a stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed.
Levopropylhexedrine
Levopropylhexedrine (Eventin) is a psychostimulant used as an anorectic in Germany and patented by Smith Kline & French in 1947.
Difemetorex
Difemetorex (INN; sold as Cleofil), also known as diphemethoxidine, is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use.
Cloforex
Cloforex (Oberex) is an anorectic of the amphetamine class.
Simmondsin
Simmondsin is an extract of jojoba seeds (pronounced "ho-HO-bah") (Simmondsia chinensis), it was traditionally thought to be a toxic substance due to jojoba seed meal causing weight loss in animals, but in year 2000 been researched as a potential treatment for reducing appetite of obese individuals by helping to reduce craving for food.
Etilamfetamine
Etilamfetamine (Apetinil, Adiparthrol), also known as N-ethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes.
Indanorex
Indanorex (Dietor) is a stimulant drug which was developed in the 1970s.
TM-38837
TM-38837 is a small molecule inverse agonist/antagonist of the CB1 cannabinoid receptor, with peripheral selectivity.
Formetorex
Formetorex (INN), also known as formetamide or N-formylamphetamine, is an amphetamine described as an anorectic which does not appear to have ever been marketed.