Flashcards: Alkaloids

Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae.

5-MeO-aMT or 5-methoxy-α-methyltryptamine, α,O-Dimethylserotonin (Alpha-O) is a potent psychedelic tryptamine.

Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and found in the seeds of Turbina corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian Baby Woodrose), and Ipomoea tricolor (morning glories, tlitliltzin).

Mescaline, or 3,4,5-trimethoxyphenethylamine, is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.

Solanine is a glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum), the tomato (Solanum lycopersicum), and the eggplant (Solanum melongena).

Gramine (also called donaxine) is a naturally occurring indole alkaloid present in several plant species.

Theobromine, formerly known as xantheose, is a bitter alkaloid of the cacao plant, with the chemical formula C7H8N4O2.

Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise lilies (Lycoris), and daffodils (Narcissus).

Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker.

Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is class Ia antiarrhythmic agent.

Nicotine is a potent parasympathomimetic alkaloid found in the nightshade family of plants (Solanaceae) and is a stimulant drug.

Hyoscine hydrobromide, also known as scopolamine hydrobromide, is a medication used in the treatment of motion sickness and postoperative nausea and vomiting.

Ergine, also known as d-lysergic acid amide (LSA) and d-lysergamide, is an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae and some species of fungi.

β-Carboline (9H-pyrido[3,4-b]indole), also known as norharmane, is a nitrogen containing heterocycle.

Docetaxel is a well-established anti-mitotic chemotherapy medication that works by interfering with cell division.

N-Methyltryptamine (NMT) is a member of the substituted tryptamine chemical class and a natural product which is biosynthesized in the human body from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine N-methyltransferase.

Glaucine is an alkaloid found in several different plant species in the Papaveraceae family such as Glaucium flavum, Glaucium oxylobum and Corydalis yanhusuo, and in other plants like Croton lechleri in the family Euphorbiaceae.

Mesembrine is an alkaloid present in Sceletium tortuosum (kanna).

Forskolin (coleonol) is a labdane diterpene that is produced by the Indian Coleus plant (Coleus forskohlii).

Vinorelbine (NVB), sold under the trade name Navelbine, is a chemotherapy medication that is used to treat a number of types of cancer, including breast cancer and non-small cell lung cancer.

Lobeline is an alkaloid found in "Indian tobacco" (Lobelia inflata), "Devil's tobacco" (Lobelia tupa), "cardinal flower" (Lobelia cardinalis), "great lobelia" (Lobelia siphilitica), and Hippobroma longiflora.

Cryptopine is an opium alkaloid.

Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H.

(−)-Magellanine is a member of the Lycopodium alkaloid class of natural products.

Peyonine is a beta-phenethylpyrrole made by Lophophora.

Stevensine is a bio-active bromopyrrole alkaloid isolated from marine sponge.

Norzoanthamine is an alkaloid found in Zoanthus species (Class Anthozoa), a kind of sea anemone.

Dihydroquinine, also known as hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.

Noroliveroline is an anticholinergic alkaloid.

Sinococuline is a bioactive alkaloid found in Cocculus trilobus.

Xylopine is an antimicrobial benzylisoquinoline alkaloid.

Aporphine is one of a class of quinoline alkaloids.

Hernandaline is one of a class of quinoline alkaloids.

Isopavine is an opium alkaloid.

Neoxaline is a bio-active Aspergillus japonicus isolate.

Nareline is a bio-active alkaloid isolated from Alstonia boonei, a medicinal tree of West Africa.

Picralinal is a bio-active alkaloid from Alstonia boonei, a medicinal tree of West Africa.

Scholaricine is a bio-active alkaloid from Alstonia boonei, a medicinal tree of West Africa.

Alchorneine is a imidazopyrimidine alkaloid found in trees in the genus Alchornea such as Alchornea castaneifolia, Alchornea floribunda or Alchornea cordifolia.

Chelidonine is an isolate of Papaveraceae with acetylcholinesterase and butyrylcholinesterase inhibitory activity.

Cinchonine is an alkaloid found in Cinchona officinalis.

Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects.

Sinomenine or cocculine is an alkaloid found in the root of the climbing plant Sinomenium acutum which is native to Japan and China.

Anhalamine is a naturally occurring alkaloid which can be isolated from Lophophora williamsii.

Castanospermine is an indolizidine alkaloid first isolated from the seeds of Castanospermum australe.

Slaframine is an indolizidine alkaloidal mycotoxin that generally causes salivation (slobbers) in most animals.

Alschomine is an indole alkaloid first identified in the leaves of Alstonia scholaris in 1989.

Anonaine is a bioactive benzylisoquinoline alkaloid, present in members of the plant families Magnoliaceae and Annonaceae It is named after the plant it was first extracted from, Annona Reticulata, which is commonly known as Anona.

Arecaidine is a bio-active alkaloid in areca nuts.

Tortuosamine is a psychoactive isolate of Sceletium tortuosum.

K252a is an alkaloid isolated from Nocardiopisis sp.

Midostaurin (PKC412) is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).

O-Acetylpsilocin (also known as psilacetin, 4-acetoxy-DMT, or 4-AcO-DMT) is a synthetically produced psychoactive drug and has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin.

Isovaleramide is an organic compound with the formula (CH3)2CHCH2C(O)NH2.

Tryptoline, also known as tetrahydro-β-carboline and tetrahydronorharmane, is a natural organic derivative of beta-carboline.

Veratramine is a hypotensive alkaloid isolated from the rhizomes of Veratrum.

Spirotryprostatin A is an indolic alkaloid from the 2,5-Diketopiperazine class of natural products found in the Aspergillus fumigatus fungus.

Cassaine is a toxic compound found within the Erythrophleum genus of trees.

Emetine is a drug used as both an anti-protozoal and to induce vomiting.

Narcotoline is an opiate alkaloid chemically related to noscapine.

Cylindrospermopsin (abbreviated to CYN, or CYL) is a cyanotoxin produced by a variety of freshwater cyanobacteria.

Perakine is a bio-active indole alkaloid isolated from the leaves of Rauvolfia.

Rhynchophylline is an alkaloid found in certain Uncaria species (Rubiaceae), notably Uncaria rhynchophylla and Uncaria tomentosa.

Tetrahydroharmol is a bioactive beta-carboline harmala alkaloid.

Yuehchukene is a dimeric indole alkaloid natural product that possesses anti-fertility and estrogenic activities.

Panicudine (6-hydroxy-11-deoxy-13-dehydrohetisane) is a C20-diterpene alkaloid of the hetisine type, first isolated from Aconitum paniculatum.

Incarvillateine is a complex monoterpene alkaloid that is a derivative of α-truxillic acid.

Anhalonidine a naturally occurring alkaloid which can be isolated from certain members of the cactus family, such as Lophophora.

Californidine is an alkaloid with the molecular formula C21H22NO3+.

Chelerythrine is a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine).

Chavicine is an alkaloid found in black pepper and other species of the genus Piper.

Cheilanthifoline is an isoquinoline alkaloid isolated from Corydalis.

Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.

The cortistatins are a group of steroidal alkaloids first isolated in 2006 from the marine sponge Corticium simplex.

Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis).

Delsoline is a hypotensive alkaloid isolated from Aconitum.

Epoxyagroclavine is an ergot alkaloid made by permafrost Penicillium.

Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.

(−)-Stepholidine is a protoberberine alkaloid found in the plant Stephania intermedia.

N-Methylconiine is a poisonous alkaloid found in poison hemlock in small quantities.

Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines.

Apovincamine is an indole alkaloid derived from Vinca erecta and V.

Kifunensine is an alkaloid originally isolated from Kitasatosporia kifunense, an actinobacterium (formerly called an actinomycete).

Stenusin is a piperidine alkaloid molecule synthesized by rove beetles of the genus Stenus Latreille.

Methylliberine is an isolate of coffee beans, tea, cola nuts, guarana, cocoa, and yerba mate.

Tazopsine is a plant-isolate morphinan.

Fagaronine is a benzophenanthridine alkaloid found in Zanthoxylum zanthoxyloides and other species in the Zanthoxylum genus.

Lamellarins are a group of pyrrole alkaloids first isolated in 1985 from the marine mollusk Lamellaria in the waters of Palau.

Hamayne is an alkaloid present in plants of the family Amaryllidaceae, including Iberian Narcissus species and two Nigerian Crinum species, reported to have acetylcholinesterase inhibitory activity.